For Novavax, ranibizumab is related to billions of dollars in annual sales, and how big is the Chinese market now? Compared with these two things, the former is obviously more important.

Moreover, they do not believe that China’s current pharmaceutical level can develop any drugs that can have an impact on their products, just like Roche did back then.

After Roche bought the "two-stage fermentation method" patent for vitamin C, it only used it as a defensive strategy instead of using this method for production. On the one hand, it wanted to continue to maintain a very high entry barrier, and on the other hand, they simply did not

They believe that China's method is an advanced method, but they do not believe in the R&D capabilities and production capabilities of the Chinese.

The consequence of this move is that with the development of reform and opening up, China's vitamin C production continues to expand. In addition to meeting domestic demand, it is even sold abroad, which has a huge impact on the vitamin C price alliance of Roche, Takeda Pharmaceuticals, and BASF.

Due to the impact, Roche had to start cutting prices.

It took them more than a year to raise the price from eighteen US dollars per kilogram to four US dollars per kilogram. Roche's use of "Lyde's chemical method" was extremely costly. The four dollars had already fallen below their cost price. They planned to rely on their own

The strong financial strength beat Chinese manufacturers to death and then raised prices again.

However, even at four dollars per kilogram, domestic manufacturers using the "two-stage fermentation method" still have enough profit margins. If domestic manufacturers do not fall, companies such as Roche will be unable to withstand it.

Roche Pharmaceuticals sold its vitamin C production plant, and Japan's Takeda sold the vitamin C plant to Germany's BASF after it ceased production. Later, BASF could not withstand the strong production capacity of Chinese pharmaceutical companies and stopped production soon after. From then on, it was only responsible for providing lemons.

Aldehydes and other production raw materials; in addition, they have also received heavy fines from many countries for manipulating prices, which can be said to be a waste of money.

Later, more than 90% of the world's vitamin C was produced by four Chinese pharmaceutical companies - Northeast Pharmaceutical, North China Pharmaceutical, CSPC Pharmaceutical Group and Jiangshan Pharmaceutical. China had absolute production and pricing power of vitamin C. These pharmaceutical companies

The slightest disturbance affects the global price of Vitamin C, and China has won the battle of Vitamin C.

Roche, Takeda Pharmaceutical and other companies withdrew from the vitamin C market at the beginning of this year, but they have not yet attracted the attention of Novavax. Moreover, the technical requirements for the development and production of vitamin C are completely different from the requirements for the development and production of anti-leukemia drugs, so Novavax has

Wa Company simply does not believe that China can produce this kind of medicine.

The person who made the report before just mentioned it. Seeing that the senior executives didn't care, he didn't insist anymore and quickly replied to Zhao Lizhong, asking them to handle the matter themselves. Zhao Lizhong was in trouble.

At the same time, several major media outlets in Europe and the United States also received anonymous emails. In the email, the sender revealed the truth about how large pharmaceutical companies such as Novavax used many bribery methods to obtain FDA approval. The email's thinking was clear and logical, and the evidence was conclusive.

There is no way not to believe this.

"What should we do now? Should the contents of this email be published?" Many media outlets have also begun to convene manpower to urgently discuss this matter. They do not publish all big news. Pharmaceutical giants have always been their big advertising clients.

If they offend the other party and withdraw their advertising, they will suffer huge economic losses.

However, there are both cooperation and differences between the media and pharmaceutical giants. This is like the relationship between domestic real estate developers and the media in later generations. If they encounter some minor problems, the media may help them cover it up for the sake of advertising fees, and then

If you are older, you may send it to the developer, hinting to the developer, look, something happened to you, should you increase the advertising fee and put in more ads? Otherwise, I will expose it to you.

If there is something really big, it must be exposed, otherwise the media's impartiality and ability to obtain information will be doubted by readers and viewers.

"The sender of this email knows the media industry very well. Look at the fact that he did not hide the traces of copying other media in the email. Even if we don't send it, other media will send it! This is really big news. If other media

The media published it, but we didn't, which is a huge blow to the reputation of our newspaper." Someone reminded.

"Perhaps we can contact those pharmaceutical companies first, inform them of this matter, and see their reaction. If they can convince all the media, we will not move for the time being." This is also a good opportunity to blackmail the pharmaceutical companies, it depends on them.

No matter how much you are willing to pay, can you control all the media?

"The sender also thought of this. At the end of the email, he gave us a deadline. If we don't publish the content after the deadline, he will publish the news on the Internet." Someone reminded, "

Now that we are in the Internet age, traditional media like us can no longer fully control the right to speak."

"This is a cunning guy. No matter what we do, the news will get out sooner or later!" After the news spreads on the Internet, they still need to report the news.

"Then let's inform Nova and them first, tell them that we will publish this email the day after tomorrow... no, tomorrow, give them a day's buffer time, just think of it as thanking them for their previous advertising expenses!" The editor-in-chief made the final decision, "

I hope their crisis management department can take care of this."

"I think their public relations department doesn't have to sleep these days!" Someone joked. Every time this happens, the crisis public relations department will work overtime overnight.

"Let our reporters take action, and everyone who can spare their hands should investigate and verify this matter, and try to dig out more inside stories!" the editor-in-chief decisively ordered. According to the reminder of this email, there are many more

Things can be mined.

This is really terrible. It seems that those who can't sleep these days are not only the public relations staff, but also us reporters! The smile on the face of the person who just made the joke froze, but he soon cheered up. This is also true for them

This is an excellent opportunity. If someone can dig out something of real value, it is not impossible for him to become famous, get a promotion, raise his salary, and become famous.

The executives of Novavax were busy negotiating with Roche, academics, and public relations companies when they suddenly learned such explosive news from the cooperative media and fell into panic.
Chapter completed!