Artemisinin is undoubtedly the pride of the Chinese people. Tu Youyou also won the Lasker Prize and the Nobel Prize for it, proving that the Chinese can also make great achievements in the field of medicine. However, in terms of application, artemisinin

The situation was very embarrassing.

China's development time was too short, and it did not know much about international business rules at the beginning. Coupled with the ultra-high threshold established by international pharmaceutical giants, it was very difficult for domestically produced artemisinin drugs to enter the international market. In 1994,

Novavax took the opportunity to purchase the international sales rights of artemisinin compound drugs from the Chinese Academy of Medical Sciences, the original patent holder of artemisinin, at a low price. After five years of development, Novavax became the first company in the world to launch fixed-dose artemisinin compounds.

Pharmaceutical companies that compound or combine medications.

Soon after, the World Health Organization recommended the use of compound artemisinin as the first antimalarial drug. Unfortunately, no Chinese pharmaceutical company complied with GMP (World Health Good Manufacturing Practice), so Novartis became the only qualified one at that time.

supplier, and has obtained a patent for compound artemisinin derivatives.

Since then, French Sanofi has also obtained some relevant patents and launched its own artemisinin drugs. This has resulted in the international artemisinin market being monopolized by Novavax, Sanofi and Indian generic drugs. Foreign pharmaceutical giants have occupied the international market.

Artemisinin drugs account for more than 90% of the market share, while China’s artemisinin drugs account for less than 10%.

This is incompatible with China's status as the inventor of artemisinin and the absolute main producer of raw materials. China has become a producer of artemisinin raw materials and can only earn meager profits under the squeeze of international pharmaceutical giants.

And because Novavax and Sanofi have monopolized the artemisinin market, they not only have the pricing power of related drugs, but also continue to squeeze the purchase price of artemisinin raw materials, resulting in the continuous decline of artemisinin raw material prices. In other words, artemisinin raw materials have continued to decline.

Most of the profits from the vegetarian industry have been grabbed by Novavax and Sanofi, leaving only a little bit of leftovers for domestic use.

"It can be said that the entry standards for the pharmaceutical industry are all set by multinational pharmaceutical giants. It will definitely be difficult for us to enter. In fact, no matter which industry is now, the situation is similar, and the same is true for the digital industry. Mobile phones, computers, playback terminals, etc., the rules and standards

They are all monopolized by developed countries, and it is very difficult for our companies to enter." Shen Long said, "However, if you don't do some things, you will never have a chance. Only if you do it can you have hope."

Isn't this the case in the home appliance and mobile phone industries? Afterwards, Chinese companies gradually caught up with or even surpassed European, American, Japanese and Korean companies, and had a certain say in standard determination meetings. In the future, they launched advanced mobile phones that were ahead of foreign companies, and the pharmaceutical industry

The road ahead is indeed more difficult than that of these industries, but since we occupy the world's largest market and have unique patents in the world, we are not without any opportunities.

"Yes, I hope this will be a good start." Director Qiao sighed, "What are you going to do next?"

"First publish the paper, let the global industry know that we have achieved what they failed to achieve, and then use Ron and others to stir up public opinion in the United States, and then use the public relations company to expand the influence, prompting the FDA to accept our review request

, carry out clinical trials." Shen Long said.

"I don't know much about the situation in the United States, but it sounds like you have considered it very carefully and are very professional. If you need any help, just ask." Director Qiao was quite pleased, "It stands to reason that your achievement is fully qualified for the award. Nobel Prize, but it is hard to say whether he will win it. The Western scientific community has always been biased against traditional Chinese medicine."

It would be great if he could win the prize in a short time. Using the influence of the Nobel Prize, there is no doubt that he can speed up the FDA review. But Shen Long thought that Tu Youyou invented artemisinin in the 1970s, but she waited until I only won the award in 2015. Even if I win the award, I will probably have to wait a long time.

Shen Long spent several days writing the paper and submitted it to the New England Journal of Medicine. The paper immediately shocked the journal. They quickly distributed it to authorities in the relevant field for review and then published it as quickly as possible.

As soon as the paper was published, it caused an uproar in the global medical community. Originally, only Chinese medical practitioners knew that the new drug launched by Shen Long could treat leukemia, but now, almost everyone around the world knows it.

Many authorities in the field rushed to Shen Long's medical clinic and pharmaceutical factory to learn about the latest progress. When they saw the medical records of patients getting better one after another, they were shocked. This result means that Human beings have conquered another terminal disease. They didn't expect that this disease would be conquered, but they didn't expect that the person who made this achievement would be a Chinese doctor, and he would use traditional Chinese medicine.

"It's incredible that the conditions of these patients are really under control and are still getting better." A senior professor from Hopkins University looked at the data that had just been detected and said with emotion, "Cheng, you have done a great job. achievements.”

"This is not the result of my own efforts, but the glory of traditional Chinese medicine." Shen Long did not take all the credit. "In addition, Professor Ma Lin, Director Qiao, Mr. Weng and many other colleagues also provided me with a lot of help." .”

"Cheng, such a miraculous drug should be available to patients all over the world. Have you started preparing to apply for FDA review now?" the professor at Harvard Medical School said excitedly. It is customary for pharmaceutical giants to bribe academia. It's a matter of fact, but it doesn't mean that every medical authority is under their control. "If you have this plan, I am willing to help you."

"Now the production scale of the main raw materials is limited, and even the domestic demand cannot be completely solved. I think maybe we can wait a little longer." Shen Long did not show too much enthusiasm, "And, as far as I know, China's drug wants to It seems very difficult to pass FDA review."

"Cheng, science should not have national boundaries. Patients in the United States also need this drug." The Harvard professor persuaded, "As for FDA review, I have rich experience in this area."

Not only did scholars come to look for Shen Long, but there were also representatives from pharmaceutical companies. Novavax was not the only one who came back this time. These companies either threatened or offered inducements, and they all wanted to get this kind of medicine from Shen Long. Drug patents.
Chapter completed!