"Boom!"

The increasingly louder knocking on the door woke up both Tian Lu and Professor Locke from their heated discussion. The only difference was that Professor Locke frowned with a look of displeasure on his face, while Tian Lu

I was shocked, and immediately felt a sense of annoyance in my heart.

"Oops! I just got too carried away!"

Regardless of Tian Lu's annoyance, after Locke said "come in", a resident doctor opened the door and walked in.

First, he looked at Tian Lu with a rather strange look. The resident doctor clicked the watch on his wrist and said with some embarrassment: "Sorry to disturb you two! Professor Locke, each applicant only has half an hour for the interview.

You have several other applicants to interview, so..."

At the reminder of the resident doctor, Professor Locke immediately looked at his watch and suddenly realized: Unknowingly, his conversation with Tian Lu had lasted for an hour and a half!

"What a shame!"

Professor Locke stood up and shook his head: "Tian, ​​it was a pleasure talking to you. It has been so long before I knew it. By the way, are you going back to Los Angeles today?"

"Yes, Professor, I have already booked a flight for eight o'clock in the evening." Tian Lu also stood up and answered honestly. According to the schedule sent to him in advance, he can leave freely after the afternoon interview.

After a slight hesitation, Professor Locke said with a smile: "So, if it is convenient, can you postpone your plan to go back? I would like to invite you to have dinner together and continue the topic we just talked about, is that okay?"

After saying that, not only Tian Lu was slightly startled, but the resident doctor also had a look of surprise on his face!

"Of course, we will bear the hotel and transportation expenses, and we will not increase your expenses!" Professor Locke immediately added. For applicants for residency training, the hospital only covers one night's accommodation and three meals.

Everything else has to be solved by oneself. Professor Locke's attitude at this time seems to be that he is afraid of Tian Lu's rejection.

If Tian Lu didn't know what was going on by this time, he would be too slow! Surprised in his heart, he nodded quickly and replied without hesitation: "Okay sir, I will go get the ticket later."

Return."

Nodding with satisfaction, Professor Locke personally sent Tian Lu out of the office.

On the bench outside the door, there were three or four applicants waiting for Professor Locke's interview. When they saw Tian Lu and Professor Locke walking out chatting and laughing, everyone's eyes showed surprise and at the same time, they also flashed with hidden dissatisfaction and hostility.

Tian Lu, who was happy in his heart, naturally did not care about the hostility of these competitors. After nodding to Professor Locke, he left the University of California, San Francisco Medical Center with brisk steps.

After walking out of the hospital door, the cold wind blew, and Tian Lu's head suddenly hurt again.

Talking to Professor Locke made Tian Lu feel relieved, and even his cold seemed to be much better. However, once the interview was over and he relaxed, all the symptoms immediately returned to him.

"It's still early, let's find a hotel to sleep in first."

Because he originally planned to go back directly and didn’t bring anything with him, Tian Lu checked out of the room in the morning. Now that he decided to stay one more day, after thinking about it, he walked towards the hotel closest to the hospital.

.....

.............................

"Chinese people are really smart!"

"Pinching" two chopsticks in his hand, Professor Locke tried to pick up a potsticker, but after several attempts to no avail, he reluctantly picked up the knife and fork again and said with a smile: "This kind of tableware tests the coordination of the fingers.

ability."

"That's because you used too little. In fact, I used it very well!" Another white man next to Professor Locke nimbly picked up the spring rolls in front of him and said with a rather proud smile.

For dinner that started at eight o'clock, Professor Locke specially selected a famous Chinese restaurant near the hospital, which made Tian Lu very grateful: on the one hand, Tian Lu was not very familiar with the etiquette of Western food, and it would be easy to make a fool of himself if he went to a high-end restaurant; on the other hand, Tian Lu was not very familiar with the etiquette of Western food.

On the other hand, since he is feeling unwell, he just wants to drink a bowl of white porridge and eat some light vegetarian food. These things are probably only sold in authentic Chinese restaurants.

After discussing the tableware for Chinese food, Professor Locke gradually got to the point: "Tian, ​​after today's interview, I had a chat with Professor Smith. He was also very interested in an idea you proposed in the afternoon. Can you elaborate further?

Tell me something?"

Hearing Professor Locke's conversation, Professor Smith, who was enjoying his meal, immediately put down his chopsticks. Although he was skeptical of the young man from a foreign country in front of him, out of trust in his old friend Professor Locke, Professor Smith

Still looking at Tian Lu expectantly.

"Well......"

After looking at Professor Smith, hesitating for a moment, Tian Lu asked with some uncertainty: "I'm sorry, Professor Smith, because I had a lot of conversation with Professor Locke this afternoon. I don't know what you are interested in?"

The Professor Smith in front of me has a good background. He is the director of the Department of Neurology at the San Francisco Medical Center. In fact, as an independent secondary discipline, neurology does not belong to the concept of internal medicine, and is quite closely related to neurosurgery.

, it is difficult to judge whether many diseases belong to the category of neurology or surgery. Sometimes it requires the full cooperation of the two departments. Therefore, the relationship between Professor Locke and Professor Smith is also quite good.

“About the blood-brain barrier!”

Professor Smith replied without hesitation!

Tian Lu was suddenly shocked!

In an instant, waves of panic surged in his heart! Tian Lu's extremely complicated eyes involuntarily drifted towards Professor Locke, who had a serious look on his face.

As expected, he is indeed a top neuromedical expert, with such a keen sense of touch and a vicious eye!

During the interview in the afternoon, it was the first time he had the opportunity to express his understanding of neuroscience in front of top experts. Tian Lu was a little carried away for a while, and inadvertently revealed some knowledge in the system that transcended reality, including how to break through blood circulation.

Brain barrier theory.

Of course, even if Tian Lu's tone was quite positive at that time, Professor Locke would only think that this was his assumption. After all, without any experiments and research to prove it, no one would think that what a young man said was the truth!

But even so, Professor Locke was still extremely shocked to find that, at least in theory, Tian Lu's idea seemed to be feasible!

The so-called blood-brain barrier, in layman's terms, is actually a defense mechanism used by the human body to protect the brain.

The nutrients absorbed by the human body and the oxygen breathed are transported to various tissues and parts by the circulatory system. Of course, drugs are no exception. Many drugs must be transported to the site of action through the circulatory system. In the end, substances between the circulatory system and human tissues

Exchange is mainly accomplished by capillaries.

The blood-brain barrier refers to the structure of the capillaries in the brain that prevents certain substances from entering the brain tissue from the blood.

Brain capillaries are different from capillaries in other parts of the world. They have a special structure, which the medical community calls the blood-brain barrier. Because of the blood-brain barrier, it is difficult for substances in the blood to enter the brain tissue through the brain capillaries.

Easy, some are easy to pass, some are difficult to pass, and some cannot be passed at all. This selective passage cannot yet be controlled independently by humans. The blood-brain barrier is like a solid line of defense to protect the brain. Just let it pass.

Approved substances enter, while substances that are not approved, no matter whether they are good or bad, or whether they are beneficial to brain tissue, will be kept out!

The mechanism of the blood-brain barrier has not been completely cracked until now. In the past century, the world's largest pharmaceutical companies have been trying to find a way to avoid or break this defense mechanism and control it safely and effectively.

Switching the blood-brain barrier to deliver drug ingredients to brain tissue to treat some refractory diseases.

This is a problem that has plagued the scientific community for many years!

Once the blood-brain barrier is successfully broken through, the treatment of some neurological diseases, such as Alzheimer's disease (Alzheimer's disease), epilepsy (horns), etc., is likely to have breakthrough developments!

Eighty years later, this problem has long been solved, and a complete set of mature theories has been formed: from the mechanism of the blood-brain barrier to the standards and principles for selecting substances to pass through, and even substances that can pass through the blood-brain barrier.

Detailed catalog!

Of course, there are several ways to control the opening and closing of the blood-brain barrier!

During the afternoon conversation with Professor Locke, Tian Lu inadvertently revealed the general principle of one of the methods. Although this method involves a large amount of chemistry, biology and neuromedicine knowledge, it is extremely complex and can be said to be the most complex among several methods.

It is complicated and has the lowest efficiency and controllability. But it is the most suitable for the development level of modern medicine! In particular, many of the previous research on this method have been basically completed in reality, that is to say, it is still established.

Based on the existing research, most of the theoretical foundations are already in place. What Tian Lu has to do is to further in-depth, summarize and improve, and find the final nail in the coffin!

It is precisely for this reason that Professor Locke was sensitive to the value of Tian Lu's theory upon hearing it.

Some people say that only true interest can make a person successful in his or her field. This is the case for Professor Locke. As a neuromedicine expert, even though he knew that Tian Lu was just a rookie who had just graduated from university, his theory still remained

The scratching made him feel extremely itchy, so after only a moment of hesitation, he contacted his old friend Professor Smith. In this regard, Professor Locke thought that there was still a certain gap between him and Professor Smith, so he couldn't wait to hope that Smith could tell Tian Lu's

Further evaluation of the theory!

Facing the expectant looks of Professor Locke and Professor Smith, Tian Lu was extremely conflicted for a moment.

The training of neurosurgery residents lasts seven years. The first four years are for training in neurosurgery clinical knowledge and techniques. The fifth year is for basic research. In the sixth year, you can also choose to continue in-depth research. In the seventh year, you will be a general manager.

Resident physician. This method of breaking through the blood-brain barrier was the research topic Tian Lu chose for his fifth and sixth years of training!

In the afternoon, Tian Lu only elaborated on the basic theory and did not give the final conclusion. For such a huge study, just summarizing and verifying the previous theory will take a lot of time and energy, and that final step

, it can even keep a research group stuck for countless years!

This is like Edison's study of light bulbs. He knew that he needed to use heat-resistant materials in vacuum bubbles, but after trying more than a thousand materials, he invented the carbonized cotton filament incandescent lamp. But Tian Lu went one step further and directly used

You know, tungsten wire is a more suitable material than carbonized cotton wire!

Therefore, Tian Lu is not worried about the negative consequences of the afternoon conversation. He has complete theories and results in his mind, which can completely save countless attempts and avoid countless failures. Therefore, even if Professor Locke knows the principle, basically

It is unlikely that you will be ahead of Tian Road.

But if we elaborate further now, it is very likely that we will give the other party more hints, and the uncontrollable factors will be greatly strengthened.

References and plagiarism are common in academic circles. When Edison invented the electric light, didn't he also fight for patents with the British Swan? Therefore, the centenary of the invention of the electric light in the UK was in 1978, while in the United States it was 1979.

It's not that Tian Lu is selfish and unwilling to share the system's knowledge with others. In fact, he hopes that others can accept the system's theory without any doubt. In that case, he will have more room for development and can use the system more efficiently.

The help. In fact, this research is too important to his future plans to allow any mistakes.

But similarly, such a research cannot be completed by Tian Lu alone!

It is impossible for him to directly write out the final results for everyone to see. It is impossible for magazines around the world to publish such a paper, especially if it involves a large amount of experimental data, which must be fully recorded. And if it is used as a theoretical inference

, if you express the basic principles, you can only make a wedding dress for others. In addition to receiving unprecedented glory, Tian Lu will get nothing!

Such research requires a team, many advanced instruments, rigorous experimental processes, and huge data results. In the end, it all comes down to money and the support of a scientific research institution!

This is why Tian Lu insists on coming to the United States for residency training. Only here can he get all this.

"What should I do? Say it, or not say it?"
Chapter completed!