After carefully peeling off the thick fat, Wang Haoming finally saw the situation inside the chest cavity. Everything was normal, with no organ lesions and no internal bleeding. It can be seen that the pig was very healthy.

Even the heart cannot see any problems from the appearance. After all, sinoatrial node dysfunction only makes the heart beat slowly occasionally, sometimes faster, or occasionally tired, stop jumping for a few seconds.

At least at the moment when the chest was opened, the pig's heart was still beating regularly and normal.

After checking the condition in the chest cavity, Wang Haoming looked at Wang Jia and said, "Professor Wang, what should I do next? Is the genetic agent you are going to test directly injected into the sinus node?"

Wang Jia nodded and took out a tube of particularly small genetic agent from a small constant temperature incubator next to him, which contained about twenty special genes extracted from embryonic pacemaker cells that had not yet been completely differentiated.

Wang Haoming reached out to take the small genetic medicine she handed over, and injected the genes into the heart of the white pig without any hesitation. There was nothing to worry about. Anyway, this is an experimental pig. If it dies, change it to another one. This can be considered a contribution to the progress of human medicine. It is more noble than being eaten directly.

But obviously this white pig was lucky. Nothing happened after being shot in the heart. Everything was normal for vital signs.

Wang Haoming said with some ease: "Okay, then this is done?"

"Well, okay, Doctor Wang can sew it, and it depends on the effect next." Wang Jia frowned and looked at the white fat of the pig, waved his hand and quickly let Wang Haoming sew it.

Ten minutes later, the blade of the white pig was sewn by Wang Haoming with a relatively high-end fish skin collagen suture. It is not painful to use the products of his own company.

"That's it. If you want to conduct surgical tests next, you can call me at any time. My office is on the first floor." Wang Haoming took off his sterile gloves full of oil, took off his mask and told him all, and then left the laboratory casually.

The next scientific research has nothing to do with him. He understands that he is just a tool for performing experimental surgery.

Before the pig's anesthesia period had passed, Wang Jia hurriedly called several researchers to carry the pig into a cage, and then ordered: "Next, you will be in groups of four people, responsible for taking care of and observing the pig, especially heart rate testing, which will be done every two hours, and enough data must be collected for comparison."

Gene injection into the pig's body does not mean that the experiment is over, it is just the beginning.

In the next three days, the heart rhythm data collected by researchers on the experimental pigs showed that the heart rhythm of the experimental pig was still somewhat abnormal, and it was sometimes fast and sometimes slow.

But starting from the fourth day, the heartbeat of the test pig, which was supposed to slow down and unstable, gradually returned to normal.

Although everyone was filled with joy, this did not mean that the experiment was successful. The first thing they did was to find Wang Haoming again and open the chest cavity of the test pig.

What's more exciting this time is that they also dissected the heart of the experimental pig tentatively named No. 1, and found from the sinus nodes of the heart that a heart cell that was not involved in controlling the heart rhythm was transformed into a pacemaker cell under the changes of genetic agents!

Or in a more professional way, it should be called myocardial self-discipline cells.

There are two types of cardiomyocytes in the heart. The first is ordinary cardiomyocytes, including atrial and ventricular muscles. This cell is also called working cells because this cell is rich in myofibrils, performs contraction functions, and is the cell that maintains the heart's work.

This kind of working cell cannot automatically produce rhythmic excitement and does not have automatic rhythmicity. In other words, whether the heart can beat has nothing to do with them. They are only responsible for controlling the heart contraction function!

As for when to contract and the frequency of contraction, it belongs to the second type of cardiomyocytes, that is, the self-discipline cell tube.

Self-regulatory cells form a special conduction system of the heart, which plays a role in controlling the rhythmic activity of the heart. How does everyone's heart beat, whether it is fast or slow, is controlled by self-regulatory cells.

Among these two, there is another type in the sinoatrial node, which has neither contraction function nor self-discipline. It only retains very low conductivity, and is a cell that cannot do anything and cannot use anything.

After this gene injection, some of these cells that are not good at doing anything are converted into normal self-regulatory cells to replace some damaged and dead self-regulatory cells to control rhythmic activities of the heart.

It is precisely because these newly transformed self-regulatory cells were added to the heart of the No. 1 test pig that the originally abnormal heart rhythm gradually returned to normal.

Unfortunately, in order to obtain this first-hand information, the heart of the No. 1 test pig, which had just been cured, was dissected and gloriously dedicated to the medical cause.

After dissecting its heart, other parts of its body were not wasted. That night, the chefs of the institute made a full pig banquet, and added a meal to all the staff at the institute.

Even though the No. 1 experimental pig sacrificed its life for the progress of human medical care, its soul was destroyed, but it still burned, illuminated all the staff of the institute, and did its last part for everyone's high-intensity scientific research career!

It can be said to be the greatness of life and the glory of death!

After eating two big bowls of fragrant braised pork with tears in his eyes, Wang Jia calmed down and led the researchers who had eaten greasy faces to start the second phase of the experiment!

The second phase of the experiment will rely on the No. 2 experimental pig and the No. 3 experimental pig will work hard!

Next, Wang Jia will do a comparison group. She greeted Wang Haoming, who was also full of drinking a bowl of rib soup, and had two more surgeries, injecting that special gene into the hearts of the No. 2 experimental pig and No. 3 experimental pig respectively.

In addition, Wang Jia also named this gene in his spare time, so he named it SYZ1 gene! To commemorate the No. 1 experimental pig!

All the scientific research and development of the entire bio pacemaker project team were full of excitement, and they felt that the research and development of the project was going smoothly, and they might soon achieve phased success.

Even Cha Lingli, the deputy of the project team, couldn't help but share the good news with other scientific researchers in the institute, and also mentioned it to her old boss Bai Bingchun.

Bai Bingchun was very happy to hear that the progress was so smooth, so he quickly notified Chen Changan again.

But just when everyone was full of joy and felt that the future of the project was bright.

The two second batch of experimental pigs injected with SYZ1 gene were treated with gene therapy and after two weeks of the heart rhythm returning to normal, the treatment effect disappeared, and arrhythmia occurred again!
Chapter completed!