Under normal circumstances, surgery is synchronized with chemoradiation and chemotherapy for 6 weeks and long-term chemotherapy for 6-12 months, which is a routine process for glioma to prolong life. Current technology can only do these.

Even so, this is just a plan that will not last long.

Simply put, if you don’t do these chemotherapy and take conservative treatment, it will be delayed by one or two years half. If you spend a lot of money, surgical radiotherapy and chemotherapy can be completed smoothly, and the results are good, you can temporarily control it and delay the survival cycle of two or three years.

As for the survival period of more than three years, the probability is less than 5%. Among the 100 patients, only four or five may be lucky enough to live for three years.

Jiang Jun did not choose to undergo surgery because his tumor grew very tricky. In the brain stem, the risk of surgery is very high and it is difficult to remove it completely, which is not very meaningful.

He only had synchronous chemoradiation and chemotherapy and followed long-term chemotherapy for half a year.

Generally speaking, half of the patients may have insensitivity problems, which means that synchronous chemotherapy is useless.

Fortunately, Jiang Jun was lucky. The effect of synchronous chemotherapy was good, but the sequelae of chemotherapy still tortured him for a long time.

Moreover, after half a year of subsequent long-term chemotherapy, the condition continued to worsen. He even had a high fever and went to the hospital. His life was in danger and his life was on the verge of death.

However, at this moment of despair, he was ready to sacrifice his life for the cause of medicine, but he grabbed another life-saving straw.

Ruikang Medical's gene editing anti-cancer research has achieved a breakthrough with the efforts of Yun Heng and Qian Zhongsen, and applied it to animals, with a very significant effect.

In experiments on gliomas, up to about 70% of the cancer cell genome can be edited, more than 70% of the cancer cells can be eliminated, and the tumor can be suppressed to a very small one can effectively prolong the patient's survival cycle.

In simple terms, it can suppress the tumor in early stages.

Generally, early glioblastoma will not have any obvious clinical symptoms. In other words, early glioblastoma patients do not affect their lives and cannot feel any physical abnormalities.

If cancer can be suppressed in early stages, wouldn’t it prolong life?

However, this has not been tried on the human body, and it is not certain how long this inhibitory effect can last. It is too early to draw a conclusion.

At least phase three clinical trials must be conducted to obtain enough clinical data to have a relatively certain therapeutic effect result.

And Jiang Jun will be the first patient to receive gene editing technology to treat cancer!

However, before conducting clinical trials, he had to receive treatment to lower cranial pressure first. Because glioblastoma grows in the brain, intracranial pressure often rises, and he had to lower the intracranial pressure first before subsequent treatment was performed.

In the next few days, Jiang Jun dealt with the problem of cerebral edema in the hospital and reduced cranial pressure.

After having hope of life, Jiang Jun felt much more relaxed. As long as he is still alive, there is still hope in everything!

Now every day he gets injections and takes medicine, and chats with his patients and brags. After he feels relaxed, he has become much more leisurely.

The only embarrassing thing is that he always has to go to the toilet, because skull pressure reduction is dehydration and diuresis, so he goes on the toilet very frequently.

Seeing hope, my father, who was in a much better mood, also joked with Jiang Jun, saying that his mother didn't run so hard when she was pregnant with him.

The doctor who was in the rounds also quipped: "No, if you put something in your body, it's different from ordinary people."

His mother had a baby in her belly, and a tumor in her brain. The two of them were indeed different from ordinary people.

A burst of laughter rang out in the ward. Not only Jiang Jun's family, but other patients were also happy.

Jiang Jun was teased with pleasure, while smiling.

This feeling has been a long time for him.

...........

After a few days of treatment for lowering the cranicular pressure, Jiang Jun's intracranial pressure dropped to normal levels, but it would rise again at any time, so without further ado, he was pushed into the operating room after signing the clinical trial notice and consent form.

Yunheng has used CRISPRCas9 gene editing technology to create an immune weapon, and used lipid nanoparticle technology as a carrier to make a genetic drug.

In the intervals of the CRISPR sequence, the cancer cell genes of glioblastoma have been stored, which is equivalent to a blacklist of viral DNA.

After Jiang Jun was pushed into the operating room, he was anesthetized because he had to undergo brain surgery this time. He had to use an invasive ventilator during the operation period, and Ichisuke directly opened his airway.

After supplying oxygen, the nurse put a bunch of electrodes on him, mainly monitoring his vital signs in real time. After all, the risk of surgery involving the head is relatively high, and all physical conditions must be grasped in detail during the operation.

After the preparations were done, the operation officially began.

The surgeon skillfully drilled a small hole in Jiang Jun's skull, then picked up a program-controlled micro-syringe that had inhaled the drug in advance, and pierced it into Jiang Jun's skull.

This program-controlled micro-syringe can adjust the drug delivery speed and automatically deliver it. It is more accurate and subtle than human control. It is an indispensable device for intracerebral injection. After all, human hands cannot master the precise injection of drugs to milligrams, nor can they maintain high-precision uniform injection.

After all the drugs in the syringe were injected, the surgeon did not pull out the syringe as soon as possible, but stayed for three minutes before slowly pulling out the syringe.

"Okay, the drug injection is over."

Yes, the operation is basically over. You can disinfect the skin and finally give Jiang Jun some antibiotics. Even if the operation is over, you can push it to the awakening room to wake up.

However, although the operation is just an injection of intracerebral injection, it is very fast and simple, it does not mean that the treatment process is also very simple.

At this time, after Jiang Jun's brain was injected with genetic drugs, a fierce battle in the microscopic world was taking place.

After the gene drug entered his brain, the lipid nanoparticles containing the Cas9 gene and sgRNA were decomposed under the action of cellular enzymes, and the internal Cas9 gene and sgRNA were exposed.

sgRNA is a guide RNA, and its function is to guide Cas9 to identify the gene targets of cancer cells!

Under the guidance of the guide RNA, Cas9 made rapid progress and soon entered the tumor in Jiang Jun's brain stem and launched a battle against cancer cells.

Cas9 is like a pair of scissors, cutting the genes of cancer cells in the tumor in a snap.

The cut genome will become linear and cannot be replicated and expressed, and will eventually be degraded by enzymes, so that cancer cells will no longer be replicated.

More importantly, the immune weapon of the CRISPRCas system is memory because the DNA fragments of cancer cells are present on the spacer blacklist, so when these cancer cells try to replicate genes, they will be cut off again.

The cancer cells raging in Jiang Jun's brain stem encountered an enemy for the first time!

And it is a very powerful enemy!
Chapter completed!