Chen Changan's life has been very comfortable recently.

Collagen sutures are being produced step by step.

Every day, fleets of dealers from all over the province are piled at the entrance of factory warehouses. As soon as there are newly produced sutures, they will be snatched away and loaded directly into major third-level hospitals, and they will never have the chance to enter the warehouse.

The patent application process also went smoothly. No strange people jumped out to stop it. The patents can be announced in another month.

At that time, you can authorize patents to those companies that have signed contracts, and you can receive the small money immediately.

The research team, which he had recruited four people, was working hard to overcome the technical requirements and production drawings of the new intelligent stapler.

Gu An, a master of mechanical engineering, who was temporarily appointed by Chen Changan as the leader of this project team, assured him with great confidence that he would definitely study the drawings and try to make them within half a year.

In general, except for the fact that recruiting scientific research talents is a bit tricky, everything else on Ruikang went very smoothly.

Chen Changan also gave bonuses to all employees of the company because the sales of fish skin collagen sutures exceeded 10 million!

Even the factory workers paid 200 yuan each. It can be said that the company is full of energy now and everyone has a bright future.

But just at this moment of comfort, Chen Changan received not very good news.

On March 3, Chen Changan arrived at his office on time at 9:30 in the morning as usual.

But before he could start processing the documents, Guan Kou put a document in it and pushed open his office with a serious look on his face.

"Mr. Chen, an influenza A pandemic broke out in Bashu, and it has spread to four nearby provinces. It may not be easy to control for a while. It is estimated that many people will be infected with influenza."

While reaching out to take over the report that Guan Kou had sorted out overnight last night, Chen Changan asked casually: "Share is type A? h1n1? Or a new subtype?"

"It's not a new subtype, the antigenicity has not produced new mutations, it's still h1n1, but this time the spread was a bit rapid. Before the epidemic prevention centers at all levels could respond, they spread rapidly in the five provinces, and now there is a trend of spreading rapidly to the whole country!"

"Oh? So serious?" Chen Changan was a little surprised. Influenza A is a common infectious disease. Basically, it will break out in a small area somewhere on the earth every two or three years.

There was also an H1n1 pandemic in China in 2010. Chen Changan remembered that he was still in the third year of junior high school at that time, and the teachers in the school used loudspeakers to broadcast every day.

Students are required to wash their hands frequently, wear masks, avoid close contact, and maintain a social distance of more than half a meter.

For a while, when the publicity was strong, the school set up a special supervision team. As long as you see a boy holding his arms and a girl holding hands, you will come forward to criticize and educate him.

That was the worst influenza outbreak in his impression. In a blink of an eye, eleven years passed, and another influenza A broke out!

Chen Changan looked at the incident report that Guan Kou had sorted out overnight with great interest, and wanted to sort out the situation, but the more he looked, the more he felt something was wrong, and the worse his expression was.

"The chance of respiratory failure in severe patients this time is very high? Now there is a shortage of ventilators in Bashu Province?"

"Yes." Guan Kou helped the frame, which was a little crooked because he rushed to deliver the documents, and explained calmly:

"Generally, a tertiary hospital has about 10 non-invasive ventilators in the respiratory department, and a non-invasive ventilator in the hematology department. No ventilator in other clinical departments in non-IICU and emergency departments do not have ventilators."

"And ICUs usually only have ten to twenty invasive ventilators, even fewer in emergency departments, and usually two to three invasive ventilators."

"Now the large Grade A hospitals in Bashu may have to accept two to three hundred patients infected with influenza A in a day, and one-third of them will cause respiratory failure ranging from mild to severe."

"It's okay for mild patients. With the support of antibiotics, the symptoms will be relieved in a few hours, but severe patients must use a ventilator to assist oxygen therapy."

"At peak hours, there are not enough ventilators in the hospital. Now the Grade A hospitals in Bashu Province are transferring patients to Grade B hospitals and secondary hospitals with ventilators to alleviate the shortage of medical resources."

Speaking of this, Guan Kou shook his head and said in a complicated mood: "But the Center for Epidemic Prevention predicts that the next half month may be the peak of the outbreak, and the number of confirmed patients every day may increase."

"Now, major hospitals in Bashu are urgently purchasing ventilators from various medical device manufacturers."

Chen Changan frowned, but unfortunately Ruikang does not have the ability to produce ventilators, otherwise he could solve his urgent problems.

"This time, several domestic companies selling ventilators are probably going to make a profit, but they deserve it, so they buy it to save their lives."

He sighed, not knowing whether it was to be glad for them or to be a pity for himself.

But Guan Kou broke Chen Chang'an's idea: "Mr. Chen, most of the major hospitals purchase imported ventilators, and only a small number of hospitals with shortage of funds have purchased some domestic ventilators."

"Why?" Chen Changan frowned and said in confusion: "Isn't ventilators a relatively low-end medical device? I remember it's quite common. Do domestic products are so bad that they are unwilling to use in such emergencies?"

Guan Kou pointed to the report in Chen Changan's hand and signaled him to turn to the last page.

Chen Changan opened and looked at it. It was the information about ventilators carefully collected by Guan Kou. He was a little puzzled. Why did Guan Kou specifically collect information about ventilators?

He didn't say that the company was going to enter the ventilator industry...

It’s not the time to think about this now. Chen Changan temporarily put this question behind his mind and read this information carefully.

..

In the current ventilator industry.

The imported ventilators such as Kehui, Maikewei, Delger, and Shameton are first-tier brands, and the remaining brands such as Conrforsten and Hameton are second-tier brands. It was Mindray and Kenshen's turn to be several domestic brands.

Compared with invasive ventilators, non-invasive ventilators use an oxygen hood to supply oxygen in a single pipeline, and the usage mode is a simple pressure mode, so many domestic brands are actually doing pretty well.

If it is for ventilation rather than treating lung diseases.

For example, most neurosurgery patients and most patients who need to wake up after surgery.

These patients have no problems with their lungs and do not require complex ventilation modes for treatment. Generally, non-invasive ventilators can meet the needs of patients.

However, patients with severe illustrative patients, patients with severe respiratory failure and patients with lung condition must use a more demanding invasive ventilator.

Invasive ventilators are roughly divided into turbine air supply and air compressor air supply from the principle of air supply.

The turbine is a fan-through speed adjustment to obtain different flow rates and pressures. Due to its simple structure and low cost, it is more used in non-invasive machines and low-end and mid- and low-end ventilators.

Moreover, since there is an acceleration process for the turbine from low speed to high speed, the turbine's response time is slow, generally delaying by about 200ms.

Although there are products that can respond as quickly as possible within 50ms, it is also the technology of top international brands.

Not available in China...

In addition, due to the unstable air flow caused by turbine rotation, its supply pressure and flow rate are often unstable.

Furthermore, the fan will be damaged due to heating during long-term use of the turbine, which has a high failure rate.

Most domestic brands are turbine gas supply!

As for the air compressor supply.

From a therapeutic point of view, the air supply pressure is stable, and the response time is generally within 20ms, which is very fast.

It is currently the preferred air supply method for high-end ventilators.

Those who have played lol should understand how big the difference is between 200ms and 20ms before!

It's a very different difference!

However, due to the complex structure, the corresponding cost is much higher, and the noise caused by the compressor operation has also been criticized by medical staff.

Although the turbine responds slowly and has a slightly higher failure rate, the noise is relatively small.

This can be considered as a sense that fish and bear's paw cannot have both.

However, most large Grade A hospitals now have central oxygen supply systems. When there is an oxygen supply system, the ventilator can use air compressors to make oxygen without using air compressors, and the noise problem can be solved.

When the noise problem can be solved, a pneumatic ventilator such as an air compressor has much advantage over a turbine!

First of all, due to the increase in the response time of the air compressor, the patient and its confrontation are smaller, so that the patient's experience of using it will be more comfortable.

In addition, air compressors have many advanced ventilation modes that low-end turbines do not have.

Such as capacitive control, pressure control, command ventilation, spontaneous breathing, bidirectional airway pressure release ventilation, non-invasiveness, air leakage compensation, etc.

Yes, high-end invasive ventilators can be compatible with non-invasive use at the same time. Just connect an oxygen mask and switch to a special non-invasive working mode, and then you can use it as a non-invasive ventilator, which is very convenient!

Moreover, the above mentioned are the basic models of the regular ones. All international first-line ventilator brands have these functions, and they are all basic exercises!

Not only that, in addition to these basic models, each of their high-end ventilator products also has one or two cutting-edge technologies.

For example, Kehui's equal proportional ventilation technology, its Newbones series' automatic exhalation trigger sensitivity!

Shameton's asv mode!

And some high-end ventilators can minimize the amount of tidal air to 3ml, which can provide invasive oxygen to newborns!

No domestic brand can do these technologies alone!

Even those basic fucks can't do it at the moment...

Domestic ventilator manufacturers can generally only make some ventilators for turbine air supply.

You can't imagine having an advanced ventilation mode.

However, turbines are actually absolutely sufficient for daily use in hospitals. Many imported turbine ventilators from the world are also very popular among first- and second-level hospitals.

Therefore, general Grade A hospitals prefer high-end air compressors and ventilators.

Small hospitals without a central oxygen supply system prefer to use cheaper and more convenient turbine ventilators.

But even if it only makes ventilators that supply turbines, if domestic brands can achieve a level comparable to international frontlines, there is still a lot to do.

However, the reality is that the equipment performance and stability of domestic brands are lagging behind many imported brands!

Domestic invasive ventilators are often prone to failure during use!

You should know that if this type of medical equipment used in intensive care fails, it is easy to cause death if it is not solved in time!

At the beginning, some hospitals were cheap and were willing to be guinea pigs, but when used for a period of time, failures occurred frequently!

Moreover, after the actual experience of using it, the doctors found that the performance of domestic equipment was also significantly different from that of imported brands!

Therefore, since then, domestic invasive ventilators have been criticized by major hospitals and are unwilling to buy and use them.

Currently, 90% of the domestic invasive ventilator market is occupied by imported goods.

As for the simpler non-invasive ventilators, the market share of domestic brands is not high, and they can barely have a market share of nearly 50%.
Chapter completed!