On the way back to the hotel, Chen Changan patiently explained to Guan Kou.

"Down syndrome in children is the most common trisomy sign at present."

"This disease is caused by chromosome abnormalities and an additional chromosome 21. 60% of children will have miscarriage in the fetus. Survivors have obvious intelligence backwardness, special faces, growth and development disorders and multiple deformities."

"Children with Down syndrome generally look different from ordinary people."

"The eye distance is relatively wide, the bridge of the nose is flat, the outer corners of the eyes are raised upwards, the outer ears are smaller than normal people, the tongue is plump and short, and it is often unable to completely contain it in the mouth, so it will drool uncontrollably."

"Height and head development are different from ordinary people, with a flat occipital part and are called "international face" by the medical community.

"This is not a good name. It means that it is not divided into races and international. Any patients with Down syndrome look the same and have a very "international style"

"The IQ of children with Down is much lower than that of normal children. Usually, the IQ of children with Down is only about 20-50, and the development of limb movements of children is slower than that of normal children. Children who do not have financial conditions to go to special schools will not even have the opportunity to receive education in their lifetime."

"However, the severity of intellectual disability is different for every patient. Some patients with milder conditions can also have an average person's intelligence level in their teens and are enough to take care of themselves, but this situation is not many."

"80% of Down's children can only live to about 10 years old, and more than 50% of patients can live to 50 years old. Most children can basically take care of themselves through patient education and training. If they survive until adulthood, they often develop symptoms of Alzheimer's disease after the age of 30."

"And male Down babies will not have fertility until puberty. Although female Down babies have menstruation and may have fertility after growing up, they have the possibility of inheriting Down syndrome and it is difficult to have a healthy next generation."

Guan Kou nodded with a serious expression. Chen Changan had already told the situation of patients with Down syndrome clearly in just a few words.

Obviously, this is a very terrible disease, and it is a genetic disease. It is born with it and cannot be changed in a lifetime. God is so unfair to babies with Down syndrome. It is born incomplete. This is even more desperate than the disease caused by accidents.

"Mr. Chen, this disease is so serious. Are there many children suffering from it? Why haven't I heard of it much before?"

Since Chen Changan obtained the medical technology knowledge that appeared inexplicably, he has not changed much in other aspects, but his memory ability has become better than before.

Basically, as long as he reads the books or any information, he can remember them in his mind, and he can be remembered by all means.

He recalled a little and remembered a data report about Down syndrome that he had read last time.

"Currently, the prevalence rate of Down syndrome varies across countries around the world, but the overall rate is between 600 and 700."

"That is, in every 600-700 newborns worldwide, one Down child will be born."

"So far, one Down child is born every 20 minutes in our country. If it is OK to check during prenatal examination, it can be taken promptly. However, some people will ignore prenatal examinations. Only after the child is born will they find that parents can only accept it and embark on a long and arduous road to parenting."

Guan Kou covered his little mouth and said in surprise: "Can this disease be detected in advance?"

Chen Changan nodded and explained: "The only way to effectively prevent the tragedy of Down's children is to prevent the birth of a baby with Down's syndrome through clinical medical intervention."

"The four pregnancy test methods, including villus biopsy, amniotic fluid puncture, Down's screening during the middle pregnancy and non-invasive DNA prenatal testing, have effectively prevented the incidence of Down's syndrome to a certain extent."

"When the results of Down's screening during a villus biopsy are high-risk, doctors generally recommend that pregnant women do non-invasive or sheep wear. Although these tests need to be paid for at their own expense, at least they can be more at ease after doing them. They can be detected early and then aborted."

"But not every pregnant woman will choose to do a series of complex and expensive Down's screening during pregnancy. You should know that this series of tests is not cheap."

"In fact, only less than 20% of pregnant mothers who take the initiative to do Down's screening during pregnancy tests. Most pregnant mothers only do some ordinary pregnancy tests, which leads to many Down's children not being discovered during pregnancy."

"And this way of achieving the purpose of preventing by termination of pregnancy is too risky and harmful to older pregnant women. The probability of pregnancy is extremely slim. If they undergo induced labor, they may lose the chance of having another baby."

"The hospital cannot give a 100% sure answer. It can only be said that the fetus may have a higher risk of suffering from Down syndrome, which gives some parents the mentality of taking chances."

"However, in fact, Down syndrome is an occasional disease. Every pregnant mother may have a Down child. Even if it is judged as low risk during Down screening, there is a certain probability that she will have a Down child."

"Every 20 minutes, a Tang family will be born in China, and the chance is no longer very low."

“Even in December 2011, the United Nations General Assembly designated March 21 as World Down Syndrome Day, and held World Down Syndrome Day in an appropriate manner to raise public awareness of Down Syndrome.”

"In recent years, the proportion of children with Down syndrome has become increasingly higher and more. There has been a trend of changing from rare diseases to common diseases, and the situation cannot be underestimated."

"But..."

Chen Changan smiled complacently, reached out to touch his nose, and said proudly: "Although Tang's son has swept the future of his children like a tide in recent years, it is a chromosomal abnormality disease, not a terminal illness, and there is actually a way to treat it."

"Although the changes in the face of the child and some deformities on his body have been fixed at the moment of birth and cannot be changed, there is still hope of improving the intellectual barriers."

"After all, chromosomal mutation is nothing more than a genetic problem, and genetic defects are in my Chen Chang'an, so there is hope that it can be treated."

Chen Changan turned his head and looked at Guan Kou with a smile, and said in a joking tone: "Don't those foreigners like to call me gene dealers? Then I should do more things that match this nickname to be worthy of this title."

"It just so happens that my master's and doctoral research direction has not been decided yet. How about this topic treating intellectual disability in Down syndrome?"
Chapter completed!