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Four hundred and sixty-one chapters in vitro cultivation

What Chen Changan said sounds like something reasonable.

Guan Kou understood, but he didn't quite understand.

It seems very simple to say, but how to activate this set of construction drawings in DNA, how to specify that only one room is built instead of building the entire building, how to ensure that the embryonic environment can be simulated in vitro, how to obtain enough primitive stem cells, and how to let them grow in the way they want.

These are all difficult problems that need to be solved.

Any of these questions can be stumped by all scientists around the world!

Moreover, Chen Changan's words are just a guess, and there is no practical theory or experiment to prove his conjecture. To this day, human medical scientists have not figured out the complete mechanism of human organ development. Chen Changan's theory of building is not necessarily correct, it can only be regarded as a conjecture.

With just this guess, I resolutely entered the field of organ regeneration, which is really unreliable!

But Guan Kou could not refute Chen Changan. After all, Chen Changan's past experience was really outstanding. Even if he said he could make Gundam, no one could question him before he failed...

Guan Kou could only suppress his doubts in his heart. She had no ability to stop Chen Changan, so she could only wait and see what had changed.

....

Ten minutes later, the two arrived at the research center and found the Wang Jia project team that was conducting dental regeneration research and development on the second floor.

"Professor Wang, how is your project progress? Are there any tooth regeneration? " Chen Changan asked directly after finding Wang Jia.

Wang Jia took a tablet and marked out an experimental document.

"At present, we try to use dental pulp mesenchymal stem cells and 3D culture technology, and have successfully cultivated regenerative dentin, capillary network, and peripheral neural network in an in vitro culture dish!"

"It's just that this is just in vitro culture, and the cycle is quite long, it takes more than a month, and it needs to be purely manual modeling. It is quite cumbersome and cannot be popularized."

"But the route should be correct. The dentin cultured and gingival nerves are almost no different from those found in humans. They can be directly cultivated in the body."

"In the next step, we plan to recruit some volunteers to conduct subcutaneous cultivation experiments for volunteers. If a healthy dental system can be successfully cultivated under the volunteers, it will be not far from the application."

The teeth regeneration project is quite pleasing.

After all, teeth are not complex organs. The most complex ones may be nerves, but Ruikang's research on the field of human nerves is still very good, especially Fu Yi, who can be regarded as one of the few people who know the human nerves best.

So with her help, the dental regeneration project went smoothly.

"Is this path feasible to use stem cells for in vitro cultivation?" Chen Changan asked with a smile.

Wang Jia said seriously: "Of course it is feasible. Dental stem cells have the potential for multi-directional differentiation. In addition to forming cells with mineralized nodules, they can also differentiate into cell lines such as fat, bone, cartilage, muscle, vascular endothelium, liver, and nerves after induction by different cytokines."

Chen Changan smashed his mouth and said with a smile: "Dental stem cells are indeed a very powerful cell, but they are still inferior to pluripotent stem cells."

"What do pulp stem cells can do, pluripotent stem cells can do, and even do better."

Wang Jia looked at Chen Changan in confusion. Everyone knew this truth. Why did he say this?

Chen Chang'an, Professor Wang, you did a great job. The organization wanted to add a burden to you and said very solemnly:

"Professor Wang, the group will launch a very large project next. It may be that you and Professor Yun's two project teams need to work together to complete it."

"This new project is to induce pluripotent stem cells and cultivate organs in vitro!"

Wang Jia opened his mouth and murmured: "That... Mr. Chen, aren't you kidding?"

Although they are all stem cells, inducing pluripotent stem cells, nurturing organs in vitro, and cultivating teeth with dental stem cells are all different things.

If the difficulty of using tooth stem cells to cultivate teeth is 1, then the difficulty of using inducible pluripotent stem cell technology to cultivate in vitro organs is 100!

Chen Changan put a big bomb up here, how could Wang Jia stand it!

It caused a lot of impact on her...

Chen Changan didn't think anything was there at all, but instead patted Wang Jia's shoulder very kindly.

"Professor Wang, you can complete your teeth regeneration project as soon as possible. The next task is very heavy!"

"I'll discuss with Professor Yun first. Their project team is now idle. The projects at hand have just been completed. Professor Yun and the others will do the preliminary research work first, but you have to speed up the pace."

After Chen Chang'an happily told Wang Jia a few words, he ignored her shocked expression and left her office with his hands behind his back.

"Let's go to Professor Yun's place next door."

Guan Kou smiled apologetically at Wang Jia, then followed Chen Changan happily. Don’t ask me, I’m even more confused than you now...

......

Yunheng's office is next to Wang Jia.

After the AIDS cure drugs were completed, Chen Changan gave a two-month holiday. Although the holiday has ended, because Chen Changan has not issued scientific research tasks, their team has not discussed the research direction for the next stage, so they are currently in a state of being on holiday.

The team members often go to the research center in the morning to check in, and then they can do other things. They live a comfortable life.

However, Yun Heng is not so idle. He has been paying attention to some of the current cutting-edge scientific research directions in the industry, formulating plans for the next stage, and other administrative work.

When Chen Changan came to him, he was planning the next research topic.

Coincidentally, among the research directions listed by Yun Heng, there are also topics in the field of inducing pluripotent stem cells.

You should know that Chen Changan first valued Yunheng's outstanding scientific research capabilities in cytology and genetics, especially in the field of gene editing, which was one of the top majors in China, so he recruited him to work for Ruikang.

The stem cell field itself is inseparable from genetics. It was originally Yun Heng's long-term research direction. The earliest cardiomyocyte healing agents are actually closely related to cytology.

It is very normal for Yun Heng to have research in the field of inducing pluripotent stem cells!

As soon as Chen Changan saw Yun Heng’s project plan, the two immediately hit it off!
Chapter completed!
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