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Chapter 469 Batch induction?

"Please look at Mr. Chen. This is our successful induced somatic cells into pluripotent stem cells based on the current published technical paper on induction of pluripotent stem cells in the scientific research community. After some simple improvements, we have successfully induced somatic cells into pluripotent stem cells!"

In the laboratory, Yun Heng led Chen Changan and introduced him excitedly in front of a petri dish.

The tiny cells that can only be seen with a microscope in the culture dish are pluripotent stem cells cultivated through in vitro induction.

Before these pluripotent stem cells became stem cells, they were just ordinary somatic cells!

But the only regret is that this induction has successfully induced less than ten pluripotent stem cells in total.

There is no way, the entire induction experiment requires purely manual operation, and one cell is required to conduct gene transcription induction work.

Not to mention it very time-consuming, it is also very difficult to deal with...

Yun Heng prepared more than 30 somatic cells at the beginning, but in the end, only 8 were successful. The rest were all induced during the experiment, and due to various operational errors, they failed.

The entire induction of pluripotent stem cell technology is really difficult.

This is also the reason why the inducible pluripotent stem cells that appeared in 2006 have not been successfully applied for more than 20 years.

Because the success rate of this technology is really too low and the efficiency is also very low.

Any medical project that requires pluripotent stem cells will require at least tens of millions of cells. No matter how bad it is, it will require more than one million pluripotent stem cells to have a practical application prospect.

As for the induction of pluripotent stem cell technology, the Japanese scientific research institution that has the most successful international research technology has only achieved triple-digit induction results.

That is, it can induce hundreds of energy stem cells at one time...

And it's purely handmade...

This size is simply the difference between ant and an elephant, and it does not have any practical application capabilities at all.

This creates a very embarrassing situation.

Everyone knows that inducing pluripotent stem cell technology is definitely the hope of the future human medical community, the only reliable possibility to replace cloning technology, and the savior in the field of organ regeneration.

However, the current induced pluripotent stem cell technology is still just a small flame.

No, even a flame is not considered a Martian at most.

Yun Heng brought a lot of people and worked hard for several months before rubbing out eight pluripotent stem cells with his hands. This requires us to provide enough stem cells for organ regeneration. I am afraid that it will take a thousand years to rub it to get the pluripotent stem cells needed by an organ...

But this does not mean that the experiment is meaningless.

At least the experiment has proved that somatic cells can be induced into pluripotent stem cells under artificial interference. This proof alone has allowed Shinya Yamaakana, who has developed this technology, to win the 2012 Nobel Prize in Physiology or Medicine!

However, the mountain stretched out, and the next research would be done by Ruikang himself.

How to induce pluripotent stem cells in batches and drive these pluripotent stem cells to nurture organs in vitro are the two most important problems facing Chen Changan.

He looked at the pluripotent stem cells in the Petri dish, reached out to touch his chin, and pondered for a long time.

"In this way, I personally took over the next research. I have some bold ideas on how to batch induce pluripotent stem cells, and the specific implementation still requires some experimental demonstration."

"Comrades, we will start to fall into a busy scientific research work next."

Chen Changan's confident smile instantly infected all the researchers present, and everyone cheered.

To be honest, although Chen Changan has rarely worked on the front line of scientific research in the past two years and has participated in everyone's scientific research projects, the psychological impression Chen Changan has left on everyone before is still very profound.

As long as it is a scientific research project that Chen Changan participated in, the progress will be very smooth. No matter what difficulties encountered during the scientific research process, Chen Changan can easily solve them!

Even if it is a plan that everyone thinks is very crazy and cannot be achieved at all, it can be successful in only one week at most.

It seems that there are no scientific research problems that are difficult to get him!

Thinking of these past deeds from Chen Changan, the researchers' uneasiness and disapproval of organ regeneration projects were instantly wiped out.

Everyone thinks that if Chen Changan takes action personally, this project may be successful!

Cheering sounds rang one after another in the laboratory.

Chen Changan raised his lips and watched everyone cheer for a while before reaching out and pressing it a few times, saying lightly: "Okay, everyone will do their own jobs and work hard. I will come up with a brief plan in the next few days. Everyone will try it first and solve it if they encounter problems."

After saying this, Chen Changan turned around and left the laboratory and walked towards the office upstairs.

He wants to prepare a suitable batch-induced pluripotent stem cell technology plan!

Induced pluripotent stem cell technology can be said to be a pre-technical condition for organ regeneration technology.

If you can't even batch-induced pluripotent stem cells, don't try to regenerate organs.

However, this is not a difficult problem for Chen Changan.

He even has complete organ regeneration technology, let alone this pre-technology?

In his mind, he mastered at least four methods to induce pluripotent stem cells in batches.

The focus of the four methods is different. One is that it is relatively expensive, but it can induce a lot of pluripotent stem cells at one time, and the number can be in billions.

The second method is relatively less expensive and the number of pluripotent stem cells induced at one time is also relatively small, but the advantage is that they last. It is like a hematopoietic device that can induce pluripotent stem cells continuously and day and night.

And the third type, to be precise, is not simply a technology that induces pluripotent stem cells, but a method that induces pluripotent stem cell technology to cultivate pluripotent stem cells.

This scheme can induce pluripotent stem cells in batches, but can only induce hundreds of thousands of pluripotent stem cells at a time. Then, iterative cultivation of these pluripotent stem cells can be carried out, and hundreds of thousands of pluripotent stem cells can be differentiated and cultivated into hundreds of millions of P1-level cells. The advantage of this scheme is that a small number of somatic cells can be used to cultivate a bunch of pluripotent stem cells.

However, the disadvantage is that it takes a long time, and it takes about 2 months to cultivate one time.

As for the last method, it is a very primitive batch-induced pluripotent stem cell technology, which should be the first generation of technology. Although it is very cheap, it has many disadvantages and the failure rate is not low. Chen Changan does not intend to consider it.

He is only planning to choose one of the second and third methods that suits the current situation of Ruikang!
Chapter completed!
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