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In the past century, the average life expectancy of humans has been greatly extended. In addition to the improvement of living conditions, another main reason is the continuous improvement of medical standards. The continuous emergence of various therapeutic drugs is a prerequisite for improving medical standards.
Medicine is a special product, closely related to human life, and is the patron saint of life. Its development history is ups and downs. The magical preparation technology and production technology are the crystallization of human wisdom.
In the distant ancient times, people knew that willow bark had certain antipyretic and analgesic effects, but they did not know what the active ingredient was. It was not until 1800 that someone extracted it from willow bark with antipyretic and analgesic effects, an active ingredient called salicylic acid.
In the following decades, in order to overcome the side effects of the drug in clinical applications and expand its therapeutic scope, industry technical experts have made many improvements to the extraction and synthesis process of aspirin. The active ingredient changed from salicylic acid to acetylsalicylic acid, and the dosage form developed to enteric-coated sustained-release tablets.
Since its clinical application, this drug has saved tens of millions of lives, eliminated or relieved the torture of illness for countless people, and created the immortal legend of the century-old drug aspirin.
Before penicillin officially became a clinical drug, humans were at a loss for the treatment of bacterial infections. The disease of tuberculosis alone had claimed tens of millions of lives in history. At that time, when people talked about tuberculosis, people were afraid of it.
In fact, scientist Alexander Fleming accidentally discovered penicillin in an experiment in 1928. However, the backward biological culture technology at that time was the lack of efficient and practical separation and purification technology, and the inability to obtain high-quality products with practical value, which led to a long time when human society failed to recognize the importance of penicillin.
Ten years later, through unremitting efforts, many scientists finally found the separation and purification method of penicillin, but these process technologies are limited to laboratory applications and are still far from the requirements of large-scale production.
Until 1941, scientists not only discovered a method to efficiently cultivate penicillin, but also successfully used corn syrup as culture medium, laying the foundation for the industrial production of penicillin.
In 1942, scientists from the University of Oxford invented the process of separating and purifying penicillin by freeze-drying. They used this technology to obtain high-quality penicillin crystals. This is a milestone technological breakthrough and cleared the biggest obstacle for the clinical application of penicillin.
Using existing process technology and with the joint cooperation of scientists and entrepreneurs, the large-scale production of penicillin was finally achieved in 1943.
Since it has been widely used in clinical treatment, penicillin has not only saved hundreds of millions of lives in the seventy or eighty years of history, including the war years and peacetime periods, but also provided a broad perspective and idea for the subsequent development of new antibiotic drugs.
The famous artemisinin has made the first Nobel Prize winner in Science (Physiology and Medicine) in mainland China. Professor Tu Youyou's success is because she discovered the ether extraction process for isolating and extracting artemisinin from Artemisia annua.
Artemisia annua is naturally widely distributed, and its effects have been recorded in ancient Chinese medicine prescriptions, but modern medicine has higher requirements for its use.
Although everyone knows that the effective ingredient of Artemisia annua is artemisinin, people have made many attempts to extract the active ingredient to make it convenient for clinical use. Either the active ingredient is destroyed or high-purity crystals cannot be obtained. Professor Tu took a different approach and started with solvent extraction and found that ether extraction is the most effective. The innovation of the extraction process has solved the problem that has plagued scientists for many years......
Eating grains causes all kinds of diseases, which is an objective reality faced by humans. General minor problems such as colds and fevers can be healed through the human body's own immune system. Some diseases, such as the major plagues that have occurred many times in history, will be in a state of no return without vaccines and drugs with significant therapeutic effects.
Faced with the new coronavirus that is raging the world and is said to coexist with humans, social life will eventually be able to get back on track by relying on effective therapeutic drugs. Some diseases, even if the drugs cannot be completely cured, can help humans relieve their condition.
There is neither a medicine for immortality nor a prescription for curing all diseases. Although the medicine itself also has the defect of "the medicine is three parts poisonous", in addition to air and water, as well as daily necessities such as food, clothing, housing and transportation, medicine is also indispensable to humans. This is a fact that no one can deny it.
It is the common wish of mankind to expect drugs with higher efficacy, smaller toxic side effects, and even no toxic side effects.
Fang Hanmin is a top student at 985 University. Not only did he obtain a PhD in Pharmacy and Pharmaceutical Sciences at Oxford University, he also became the project director of the European RGP New Drug Creation Center. However, during a official performance, due to an aircraft crash, he traveled from the 21st century to the late 1970s and possessed a temporary worker with the same name and surname at Hongxing Pharmaceutical Factory.
As an overseas innocent man, although he is in Europe, Fang Hanmin will return home sooner or later, but he did not expect to come back in this way.
It was a one-way ticket for traveling through time. Realizing the real situation, Fang Hanmin felt relieved. He was a PhD in Pharmaceutical Sciences at Oxford University and the project director of the RGP New Drug Creation Center. Faced with the backward production process of Hongxing Pharmaceutical Factory, he felt that there was a place for him to use...
Chapter completed!