The five of them were still lying on the ground moaning.
They only felt a burning pain in their buttocks.
"Who did you mess with? You can beat me so well. It hurts me to death. Fortunately, there is no one else here. Don't get your ass picked off and beaten. It's really embarrassing."
All four people complained about Huang Mao.
They are like a cat that failed to catch a fish, but instead made a mess.
Bad luck.
Huang Mao was unable to refute the complaints of several companions.
He turned his head and looked at the scenery in the distance, his eyes filled with despair.
‘I don’t want to either~’
He touched his butt, leaving a tear of humiliation silently in the corner of his eyes.
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Lu Ning was studying at noon and afternoon and preparing some materials for the experiment.
The next day, he rushed to Donglin Community in Yanjing City.
This time the laboratory is in the villa area nearby.
Yan Xuejun was already waiting for him at the door.
As soon as he arrived, he asked Lu Ning to sign a contract with him.
The main content of the contract is that the equipment inside cannot be damaged. If damage is caused, a series of compensations will be made.
It is also required that in addition to the original rent of 10,000 yuan, a security deposit of 10,000 yuan must be paid in advance.
For the sake of research, Lu Ning had no choice.
Sign, sign, and give money.
He paid back 70,000 yuan to his second uncle's family, and now he has given another 20,000 yuan. The 100,000 yuan in Lu Ning's pocket is about to bottom out before it warms up.
Yan Xuejun took Lu Ning to change clothes outside, put on anti-static safety shoes and masks, and then the two of them entered the laboratory.
The laboratory is about one hundred square meters and is filled with various instruments and equipment.
There are a wide variety of culture vessels.
Some transparent cabinets seem to contain strong acid and alkali liquids.
After receiving the money, Yan Xuejun was worried that Lu Ning wouldn't be able to use the instruments because of the different styles, so he briefly introduced the use of various instruments to Lu Ning.
Among them are molecular detection equipment such as electron microscopes, PCR machines, gel imagers, electrophoresis equipment, etc.
Of course, DNA extraction equipment, DNA quality control equipment, first-generation sequencing equipment, PCR equipment, and high-density chip scanning equipment are all indispensable.
In order to be wary of Lu Ning, it seems that a lot of things have been taken away from the research room.
At least several test benches are empty.
However, Yan Xuejun still warned Lu Ning some precautions, especially that some closed cabinets should not be opened at will.
Except for instruments and petri dishes, most things are not allowed to be touched.
Before leaving, Yan Xuejun pointed to the surveillance camera next to him and said, "You are just here for research, so be careful."
This is someone else’s territory. Lu Ning could say nothing but nod his head to express his understanding.
After Yan Xuejun left, Lu Ning began to conduct research.
I have two days, which is plenty of time.
For this research, he plans to start with tardigrades and his own blood.
Let’s talk about tardigrades first.
After Lu Ning's detailed search, he discovered a key point in the evolution of the tardigrade, that is, it can steal gene fragments from other organisms.
Steal genetic fragments from other creatures to evolve yourself.
Tardigrades are simply veritable DNA thieves in the biological world.
This is so similar to Lu Ning’s current copying ability!
This is the breakthrough.
According to research, nearly 17.5% of the tardigrade's genome is mostly composed of exogenous DNA, but it was not stolen from animals, but moved from non-animal sources.
Such as plants, bacteria, fungi and archaea.
However, Lu Ning guessed that there should also be genes from animals.
The researchers found that in some cases, foreign genes replaced some of the tardigrade's own genes. However, the genes that were not replaced in the tardigrade, although they still maintained their own functions, were merged into one or more genes.
Single or multiple fragments of genetic material from several bacteria.
To this day, tardigrades are still stealing genes from other organisms.
Sometimes Lu Ning wonders, did he accidentally fuse the genes of a tardigrade when he was struck by lightning that day?
How do tardigrades steal genes from other organisms?
The reason is that when a tardigrade is affected by harsh external environments, its body will slowly lose moisture and begin to dry out in order to ensure its own safety.
When dehydrated and dried out, their genomes will break.
The genome will break, this is a key!
When water is replenished, the cell membrane of the tardigrade cell will still maintain a leaky state for a period of time. When the cell quickly repairs its own damaged DNA, it will also bring some DNA from the external environment into the cell and embed it into itself.
of the genome.
In order to achieve the purpose of evolution.
In layman's terms, it means breaking and then building.
Constantly being damaged, and then constantly absorbing the genes that can survive in the harsh environment, making oneself stronger and stronger.
For example, if you are in the desert, copy the genes of the plants living in the desert.
When you come to the sea, copy the genes that can survive in the sea.
Change with the environment and truly adapt to all environments.
According to research, tardigrades contain more than 6,000 foreign biological genes.
It relies on stealing genes from other creatures to make itself more and more perfect.
In the end, he became the most powerful creature that was immortal!
"It's really strong."
Lu Ning couldn't help but sigh.
This is a real creature.
How can you be so good as the same biological creature?
However, this also proves in disguise that the developability and feasibility of organisms lay the foundation for evolution.
At the same time, it also gave Lu Ning hope.
He was wondering if he had suffered a genetic collapse at that time.
That night, I suddenly felt thirsty. I didn't want to be dehydrated and dry.
Is the body protecting itself?
If we had followed the example of tardigrades and immediately copied the genes of other organisms, would we have succeeded?
Shaking his head, Lu Ning stopped thinking and began to monitor his blood.
Lu Ning squatted on the ground, avoiding the camera, then took out a knife and cut his skin hard.
Now his skin is so hard that it can't be cut without applying force.
He tested it at home and found that it was difficult for an ordinary long needle to pierce his skin.
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After drawing a large tube of blood.
Lu Ning squeezed the blood into a glass tube, and then put the tube of blood into a centrifuge.
It didn't take long to get plasma and serum.
The top layer of the test tube is serum, the middle layer is white blood cells and platelets, and the bottom layer is red blood cells.
Lu Ning took them one by one under the electron microscope and began to observe them.
No molecular structure can be observed under a microscope, and all Lu Ning can see is the basic structure of chromosomes and viruses.
Through research, Lu Ning immediately discovered the abnormalities in his own blood and that of ordinary people.
In addition to abnormally active white blood cells.
His blood is also filled with a special virus, which is a retrovirus.
It looks like a small human brain.
What is a retrovirus?
Retroviruses are RNA viruses. Their genomes are encoded on a single strand of RNA. The viruses have the ability to penetrate cells and can effectively infect stem cells, tissue cells, skin cells and other types of cells. When the virus enters the cell, it passes through
Through reverse transcription, RNA is converted into a double-stranded DNA molecule, and the DNA enters the nucleus and is integrated into the host cell genome.
It uses viruses as vectors to introduce exogenous functional DNA into human cell chromosomes through infection.
To put it simply, it is nature’s automatic gene editor.
Act as an intermediary.
On Earth, in recent years, some defective viruses have been designed and constructed to make retroviruses useful gene vectors, successfully transferring drug resistance genes into human hematopoietic precursor cells and expressing them in the cells.<
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Retrovirus is a type of RNA virus.
And what is rna virus.
There are many RNA viruses, such as: HIV, hepatitis C virus, Japanese encephalitis virus, all influenza viruses, rhinovirus, polio virus, new coronavirus (covid-19), etc.
Lu Ning was shocked.
But he calmed down quickly.
In fact, the human genome is filled with remnants of ancient retroviral infections that invaded the reproductive system of primate ancestors.
A small number of human endogenous retroviruses have well-defined biological roles, but these biological roles are largely fluid, in other words, not shared by everyone.
These endogenous retroviruses of Lu Ning seem to be fixed.
It can be used by him.
This is simply a miracle.
"That is to say, my retrovirus has mutated, allowing me to infect the genes of other organisms through it, thereby achieving evolution."
In order to test this idea, he began to separately extract the retrovirus from his blood and began to culture it.