Chapter 576 Do you want a market worth hundreds of billions?
It is no small matter that a microorganism has been upgraded two levels in a row to reach LV3.
Of course Chen Xiao takes it seriously.
Chen Xiao has seen the power of technology trees.
When the level of microorganisms reached the first level, technological products such as combined colonies appeared.
And it can completely treat severe lung diseases that have not been able to be cured for thousands of years in human history.
Then the level of microorganisms will be raised to level three.
What kind of follow-up effects will there be?
What kind of technology products will there be?
Chen Xiao is looking forward to it very much.
Chen Xiao was even able to conclude.
Under special conditions, the combined colony can secrete peptide hormones that are very similar to insulin. This may only be a superficial phenomenon.
There may be some more exciting principles underlying it.
Chen Xiao arrived in Suhang City that evening,
Shu Rou and Gao Miao greeted Chen Xiao at the airport.
Gao Miao also arrived a few days ago, and she is taking the lead in preparing the energy laboratory here.
When she heard that Chen Xiao was coming today, she gave up her rest at night and came with Shu Rou to pick her up.
In the car, Shu Rou briefly reported on the current situation of the joint colony and patients.
Shu Rou said: "Master, it has been three days since the operation for this patient named Ding Kang. During these three days, we only replenished him with water. We were replenishing electrolytes the day before, but in these two days,
Electrolytes have not been replenished, but his vital signs are intact."
"We have sampled three combined bacterial colonies from the patient's body and cultured the colonies, and everything is normal now."
Shu Rou, Qu Ping and Huang Ling, the three of them followed Chen Xiao before they graduated from Xia Guo Academy of Sciences.
So I habitually call Chen Xiao master.
Chen Xiao didn't object. As time went by, everyone got used to this title.
Chen Xiao nodded and said nothing.
He was indeed very tired during this time.
First, prepare for the listing of Yuedong Internet, and finally find a way to raise funds from the listing of Yuedong Internet and get Changtian Technology to use it for the research and development and production of chip equipment and chips.
Then he went to Shanghai non-stop to supervise Yanjiang Semiconductor to establish the 65-nanometer lithography machine project and officially start the research, development and production of lithography machines.
The work over there has not yet been arranged, and there is a new situation on Tianyue Island.
Therefore, for three to four months, Chen Xiao's spirit has been tense and he has not relaxed at all.
The car was bumping on the road, and Chen Xiao fell asleep in the back seat, breathing evenly.
Shu Rou was still reporting at work, and when she heard her boss snoring slightly, she wisely chose to shut up, then looked in the rearview mirror and stuck out her tongue at Gao Miao.
Gao Miao smiled and looked at Chen Xiao beside her.
Seeing Chen Xiao still frowning even though he was asleep, I couldn't help but feel a little distressed.
Thinking that Chen Xiao was at work on New Year's Day in 2006, and the Spring Festival was coming up in a few days, he might not have time to return to his hometown in Jiangcheng.
Gao Miao took off his thick coat and covered Chen Xiao.
Otherwise, there will be no air conditioning after getting off the car, and you may catch a cold accidentally.
Shu Rou couldn't help but said: "Sister Miao Miao, Mr. Chen has arranged to report to him the relevant information immediately after arriving at Tianyue Island, and also hold a special meeting. You see..."
Gao Miao smiled helplessly and said, "Let's forget it tonight. I'm not in a hurry. I'm a little worried that his body won't be able to bear it."
Shu Rou nodded and agreed with Gao Miao's suggestion.
Gao Miao is considered a veteran of Changtian Technology and is a close confidant of Chen Xiao, so what she says still carries a lot of weight.
At 3 o'clock in the morning, everyone finally arrived at Tianyue Island.
Gao Miao asked Shu Rou and the others to go back and rest first. He asked his assistant to bring a quilt down, cover Chen Xiao with it, and let Chen Xiao rest.
She didn't wake Chen Xiao up. After all, if she was woken up from this kind of sleep, it would be difficult to fall asleep later.
Almost two hours later, Chen Xiao finally woke up.
He was fascinated by the lake and asked: "Are we here?"
Gao Miao looked at Chen Xiao's dazed look and couldn't help laughing and said: "It's already two hours, let you sleep comfortably in the car for two hours."
Chen Xiao smiled sheepishly, but actually she was a little touched.
Whether it is Wang Xiang or Gao Miao, these are veteran figures who have shared the joys and sorrows with him.
He is also the person Chen Xiao trusts most.
Gao Miao said: "I took it upon myself to ask Shu Rou and the others to go back first. Let's talk about the special meeting tomorrow. You should go back and rest early!"
Chen Xiao nodded and said, "I listen to you, Sister Miao Miao!"
Gao Miao couldn't help laughing.
After Gao Miao graduated, the two of them rarely spent time alone together like this.
The last time we got together so late, we were doing experiments on lithium batteries in the laboratory.
Chen Xiao was also sleepy. After returning to the suite on the top floor of the headquarters, he lay on the bed and fell asleep.
Early in the morning of the second day, it was in the conference room of the critical care center.
Qu Ping's team and Chen Xiao are in the conference room.
This meeting was very confidential because it involved the variation of microorganisms, or evolution.
Qu Ping's team has conducted a systematic analysis of the combined colonies removed from Ding Kang, including analysis of the DNA structure.
Finally, it was discovered that Rhodospirillum and cyanobacteria had mutations in the annotated BD-T12 gene.
It is precisely because of this mutation that the combined colony is able to metabolize peptide hormones, a type of metabolite that is beneficial to the human body.
And it is precisely because of mutations in this gene that the metabolism of peptide hormones will change according to the chemical conditions of the human blood.
Qu Ping showed Chen Xiao the laboratory analysis results and said in disbelief: "I didn't expect such a result."
"The precise timing and dosage of peptide hormone secretion is completely comparable to that of insulin. If I didn't have an understanding of the joint colony, I would even suspect that this joint colony is a part of the human body, or even an organ or tissue of the human body."
Qu Ping added: "At present, our samples have been cultured and a control group has been set up."
"The results of the culture revealed that this time the genetic mutation is a relatively stable phenomenon."
"We place the colonies in a human-like environment and ensure that the blood sugar of the body fluids exchanged with the colonies is stable. The peptide chemicals can play some normal roles and will not undergo other mutations due to changes in the external environment."
"From this we can infer that the genetic mutation of the joint colony this time should be a stable mutation."
"We have refrigerated some of the first-generation colonies as a precaution."
The purpose of being prepared is to prevent other mutations in future progeny colonies, which will cause some functions of the existing colonies to disappear.
After Qu Ping finished her report, she waited for Chen Xiao's feedback.
No matter how you say it, Chen Xiao is still a level 3 microbiologist, so he has a deeper understanding of the sensitivity of some data and the principles of experiments than Qu Ping.
Chen Xiao said: "If this type of bacterial colony can be stabilized, it will definitely be a good way to improve blood sugar levels in diabetic patients."
"But so far you have only tried it in a laboratory culture environment, not in an actual animal or human environment."
"So, the relevant materials are not sufficient yet."
Chen Xiao flipped through the information provided by Qu Ping and said, "But I just looked at the materials in detail, and there are a few things that we should pay attention to."
"The first one is the metabolites of fungi, which can be completely absorbed by the human body and can ensure normal vital signs of the human body."
"This shows that the metabolites of the bacterial colonies contain energy substances, electrolytes, and other necessary elements necessary for the human body."
"What exactly is it? I hope the laboratory can increase its analysis efforts and figure out the type of each compound."
"If our inference today is correct, then congratulations, we may have opened a new field in the biological world!"
"First of all, hundreds of millions of diabetic patients across the country may be able to get the most fundamental treatment. They do not need to take normal medications before and after meals, nor do they need to take insulin before meals or when blood sugar is unstable."
"This will greatly reduce the burden on people with diabetes."
"I asked my assistant to get some data from the relevant departments yesterday. This data may be able to give you some stimulation."
Chen Xiao smiled when he said this.
"Currently, most of the diabetes-lowering drugs in China are metformin, sulfonylureas, glinides, etc., as well as some insulin injection drugs."
"Take metformin as an example. The national sales reached more than 2 billion RMB, which was more than double that of the previous year."
"And that's the total sales after Medicare negotiated a massive reduction in drug prices."
"If you include other types of hypoglycemic drugs and insulin injections, the total value of the entire Xiaguo diabetes drug market should be tens of billions."
"This is only a market in mainland China. In many overseas countries, the total annual sales of hypoglycemic drugs, insulin injections and other auxiliary treatment drugs should be more than 100 billion RMB."
But Qu Ping's people sounded quite excited. This is a quite scary market.
And this kind of market is sustainable and growing.
Although doctors should talk about saving lives and healing the wounded, they should not talk about profits.
But the reality is that with the deterioration of the ecological environment and the improvement of the quality of life, the pressure on adults has increased, and there are definitely more and more patients with diabetes.
Many people, especially older people, will encounter endocrine disorders, followed by insufficient insulin secretion, and develop diabetes.
And currently, diabetes is the fastest-growing disease not just in Xia Kingdom, but in many countries around the world.
The annual growth rate is around 10%.
The growth in the number of patients also means growth in the entire drug market.
At present, in the Xia continent, sugar-control drugs are basically controlled by overseas pharmaceutical companies.
Nowadays, almost all domestically difficult drugs are imported drugs.
In Chen Xiao's memory, this kind of thing will receive attention in about 10 years, and domestic pharmaceutical companies will gradually develop their own research and development or seek overseas patents to produce corresponding drugs.
But according to the ethics of a Western company, patent fees are definitely indispensable.
In addition, Western medical technology is 10 years ahead of domestic medical technology.
After you develop the corresponding drugs, Western pharmaceutical companies will have more advanced anti-diabetic drugs and continue to strategically target the global market.
This trick has been tried and tested many times in the competition between Western technology companies and Xia Guo Company, and it has repeatedly stolen your wool.
Therefore, core technology must be in one's own hands.
Only in this way can it be safe.
Chen Xiao immediately told Qu Ping: "First form a paper based on the existing information and experimental data."
"Let's publish the paper first and then occupy the high ground in academia!"
"The following animal experiments and clinical experiments must not be missing. I ask you to understand the principles."
In fact, what Chen Xiao cares about is not just the market worth hundreds of billions.
It is about the hundreds of millions of Xiaguo patients who are susceptible to diabetes and whose lives have been greatly affected, and the families behind them.
If there are three people in a family.
That would be a population of 300-600 million.
If the combined bacterial colony can truly cure diabetes completely, Chen Xiao will gain great influence.
These influences will help light up the technology tree and even help conquer chip technology as quickly as possible.
After the meeting.
Qu Ping's team immediately became busy.
Because of their experience in combined colony culture and experiments, the team was more comfortable conducting experiments this time.
Qu Ping herself quickly formulated a corresponding experimental protocol. According to the industrial protocol and experimental plan, the animal experiment is expected to produce results within a month.
At the same time as the paper is published, if the animal experiments have good results, the team can immediately apply for clinical trials to the relevant national departments.
Chen Xiaozhe and Shu Rou's people went to visit the patient Ding Kang.
Chen Xiao is wearing a white coat and a mask.
So even if you are walking around casually in the inpatient ward, no one will recognize you.
Ding Kang and his family just regarded Chen Xiao as one of the doctors without much thought.
They thought Chen Xiao came for ward rounds every day.
My body has recovered more than half of its strength, and now I can not only speak but also walk in the ward.
What he wants most now is when he can go home.
So after meeting Chen Xiao, I immediately started talking about Chen Xiao:
"I have been living here for more than a week. Now I can eat, sleep, walk and talk. Doctor, when can I go back?"
Chen Xiao suddenly asked abruptly: "Have you eaten anything in the past few days?"
Only then did Ding Kang think that he didn't seem to have any feeling of hunger or empty stomach in the past few days.
So I didn't want to eat at all.
There is also no desire to eat.
He also shook his head in a strange way and said, "I'm surprised about this. Why don't I want to eat after the operation?"
Hearing this, everyone couldn't help laughing.
But Chen Xiao suddenly realized a problem.
If Ding Kang can maintain his vital signs even if he doesn't eat for a few days after the operation, this kind of thing will be reported.
So what impact will it have on Changtian Technology?
Chen Xiao's heart skipped a beat when he thought of this.
Will Ding Kang be regarded as a monster?
Will this series of treatment solutions from Changtian Technology be accepted by society?
Rather than passively accepting the torture of public opinion, it is better to directly announce some scientific research results to the outside world.
That is to say, the paper must be published immediately.
But before that, it would be best for Ding Kang to stay in an intensive care center.