Before taking it to humans, Sun Shichang and others conducted preliminary tests on animals.
Animal testing precedes clinical trials, starting early in life.
In order to ensure the effectiveness of the experiment, Yang Qingyuan specially ordered the six-door policemen with better physical skills to catch a few monkeys in the mountains outside Jinling.
Because of the previously effective decoction, the critical situation in Jinling City has been alleviated. Although the epidemic cannot be cured, most of the critically ill patients are no longer in danger of death. The medical team headed by Sun Shichang has time to conduct more accurate experiments.
The newly prepared medicine has achieved excellent curative effects on both monkeys and dogs. After just two doses of the decoction, the monkeys and dogs infected with the epidemic virus gradually returned to normal.
Therefore, Sun Shichang and others decided to officially try this medicine on people.
The first person to test the medicine is very important. The medicine at this time has just been developed, and Ji Mingzhu's southwestern poison detoxification method has been added to it. Even for Sun Shichang, it is a completely unfamiliar field.
In medicine, the unknown represents the risk of death.
"Brother Qingyuan! Chen Danlin asked her to take the sick brothers from the six gates to test the medicine!" Just when Yang Qingyuan and others were considering who would be the first batch of people to test the medicine, Zhou Zhiruo stood up and said.
"Dan Lin, wasn't she fine yesterday?!"
Chen Danlin is an outstanding graduate of Dali Temple Criminal Law College and one of the six detectives who escorted Yang Qingyuan to Yangzhou that day.
During these days in Jinling City, Chen Danlin also played a big role, especially in yesterday's arrest operation. This person led the policemen of the six sects to capture dozens of Blood River Sect evil disciples, and immediately
Great work.
"Ever since you started testing the medicine on monkeys, Dan Lin has taken the poisonous water by herself, and now she has developed the disease of epidemic poison!"
Yang Qingyuan was silent when he heard this.
I didn’t expect how cruel Chen Danlin could be to me!
Speaking of which, Chen Danlin is the real protagonist of the female novel. She was born in the Linhai Marquis Mansion of the Great Zhou Dynasty, and is the daughter of Chen Pu, the contemporary Marquis of Linhai. In a sense, she is a noble daughter of a noble family, with a body of gold.
But unfortunately, she was born as a concubine, and her mother was just the daughter of a merchant. Her mother passed away after giving birth to Chen Danlin. Chen Danlin was raised by a nun in the Linhai Marquis Mansion.
Just like any ordinary boudoir storybook, Chen Danlin has been bullied by her aunt and daughter-in-law. However, she endured it and practiced martial arts secretly, and finally found an opportunity to escape from the Linhai Hou Mansion.
When Yang Qingyuan founded the Dali Temple Criminal Law Academy, he began to expand the number of students. Later, Yang Qingyuan defeated Beigan in two battles in the northern border. His reputation was as high as ever. After being granted the title of Marquis of Wuxiang, Yang Qingyuan had the appearance of being the first person in the Zhou Dynasty military.
Chen Pu was just a third-generation rich man. Although he knew how to bow, horse, ride, and shoot, he was essentially a playboy who was protected by his ancestors.
At that time, I saw that Yang Qingyuan's rise was unstoppable, and I immediately wanted to make friends with him.
Chen Danlin seized this opportunity and persuaded Chen Pu to join the Dali Temple Criminal Law Academy.
But what happened next was different from what Chen Pu thought. Chen Danlin came out of the cage like a bird and had a world of her own. Not only was she promoted to the rank of storm chaser in the Six Gates, but she also made friends with many masters of the Dark Six Department.
"His ambition is so strong that he won't give in to men!" Of course Yang Qingyuan knew that Chen Danlin had her own little thoughts.
She originally had a certain reputation in the Six Sects. If she tried the new medicine on her own this time, she would not only make Yang Qingyuan and Sun Shichang look at her in a new light, but she could also capture the hearts of the Six Sects of Jinling. This girl
At this time, I am afraid that he is already seeking to be released.
What's more important is that for such a great achievement as testing medicine, Yang Qingyuan will definitely write it down in a memorial and ask for a reward.
I'm afraid she can still be in the sight of the cabinet and the emperor.
With such scheming and courage, he can indeed be called a hero among women.
However, although the benefits are great, the risks are also not small. If this potion fails, it may cost your life.
"..."
After a moment of silence, Yang Qingyuan nodded towards Sun Shichang, and Sun Shichang said, "Then I can only help you guys from the Six Doors to test the medicine!"
The medicine was then boiled in water and carried to the six-door infected ward.
"Yang Hou!"
"Chief of the mountain!"
"grown ups!"
When the people at the six gates saw Yang Qingyuan walking in with medicine, they all wanted to salute. However, most of them were tied up to prevent random grabbing, so it was inconvenient to get up.
Most people named "Yang Hou" are from the Liumen branch of Jinling.
"Shan Chang" is the title given to graduates of Dali Temple Criminal Law College.
And those who call Yang Qingyuan "Sir" are all old people recruited when Dali Temple was rebuilt!
After Yang Qingyuan comforted everyone who was sick, he came to a cubicle where twenty agents who were infected with the epidemic virus were lying and preparing to test the medicine.
Fourteen boys and six girls.
There is a thick white curtain separating people.
Yang Qingyuan bowed to these twenty people and said, "Gentlemen, please!"
The courage to test the medicine is better than the first to arrive!
Chen Danlin picked up the medicine bowl and drank the liquid in one gulp. Then, the other agents also drank.
But judging from this action, Chen Danlin has undoubtedly become the invisible leader of these agents.
This girl is indeed extraordinary!
After twenty people drank the potion, Yang Qingyuan, Sun Shichang and others waited in this compartment.
Several doctors have prepared pen and ink to record the reactions of these patients after taking the medicine.
The first person to react was a male detective in his twenties. His face became increasingly red, and Yang Qingyuan immediately noticed something unusual.
"puff!"
The male detective suddenly spurted out a mouthful of blood, screamed and fainted!
When Sun Shi saw this, he immediately stepped forward and grabbed his pulse.
"No, this bowl of medicine is too strong! Get the needle!" Sun Shichang withdrew his left hand to feel the pulse, and then took a little action, inserting needles into his Tanzhong, Chengshan, and Baihui points.
Then he took out a heart-protecting pill from his arms and drank it with warm water.
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These agents are all martial arts practitioners, and their physiques are better than ordinary people. The potency of this medicine is so strong that they cannot bear it, and it is naturally even more difficult for ordinary people to bear it.
After that, the symptoms of the two people were normal. After taking the medicine, the fever in their bodies subsided and they started to get better.
The liquid medicine that the twenty people just drank was ten different doses of medicine, working in groups of two.
Sun Shichang needs to fine-tune the amounts of various medicinal materials based on their clinical responses.
The title of King of Medicine is by no means unearned. His control over the potency and properties of medicine has reached a superb level, and there is absolutely no wrong way to use medicine!
"Uh!" Chen Danlin suddenly screamed and grabbed her arms with her jade hands.
Yang Qingyuan has been observing the movements of each patient from the sidelines. When Chen Danlin appeared abnormal, he took action as soon as possible, using the technique of tapping acupoints and cutting off the pulse to temporarily make it difficult for her to move!
Although her body could not move, her face was still twitching, and the jade face that was originally heroic and charming was now extremely ferocious.
And she was not the only one, the other nineteen people also had such reactions.
Fortunately, Yang Qingyuan restrained them all in time and ordered people to tie them up with ropes.
"Senior Brother Sun! What is going on?"
After Yang Qingyuan dealt with these people, he asked.
Sun Shichang frowned, "Our medicine is effective against this epidemic poison, but it ignores one problem. The medicine works from the inside out, and the red sores on their bodies become more painful and itchy under the influence of the medicine."
Although this itching is not a life-or-death condition, it must be addressed.
The spirit and endurance of the detectives present were better than those of ordinary people. They couldn't bear it, and ordinary people certainly couldn't bear the pain and itching caused by stress attacks.
It is easy to relieve itching, but it is troublesome to add medicinal materials without affecting the current potency.
The current dosage of medicinal materials was tested after everyone had considered it for a long time. Once new medicinal materials are added, it may break the current balance of medicinal power.
The monarch, his ministers, and his envoys should use it with their heart in mind. On the contrary, they should be afraid of evil and immediately see good and bad luck.
Li Binhu stared at the prescription in his hand over and over again. In a sense, his understanding of herbal medicine was better than that of Sun Shichang.
"Yes! Master Sun! I wonder if I can use datura flowers and castor beans as adjuvants!?"
The monarch and his ministers assist envoys, and there are three types of auxiliary medicines.
The first is adjuvant medicine, which means assisting the monarch and ministerial medicine to strengthen the therapeutic effect, or directly treat secondary syndromes.
The second is adjuvant medicine, which is used to eliminate or slow down the toxicity or potency of the primary and secondary medicines.
The third is anti-adjuvant drugs, that is, according to the needs of the condition, drugs that are opposite in nature and flavor to the monarch drug and can play a complementary role in the treatment are used. The efficacy of adjuvants is less than that of the minister drug, and the dosage is generally lighter.
What Li Binhu proposed here was to use datura flowers and castor seeds as auxiliary medicines to alleviate the strong medicinal power of the medicine of the emperor and his ministers.
Datura flowers can relieve pain caused by sores and ulcers, and relieve cold and wheezing.
Ricinus bean can open the meridians of the orifices, relieve pain, reduce swelling, chase pus and remove toxins.
Both of them have miraculous effects in treating sores and analgesic, and can just relieve the painful itching of red sores caused by the power of Junchen's medicine.
Sun Shichang, who was thinking, his eyes lit up.
"What a wonderful use! Near the lake!"
These two flavors are not only symptomatic, but also have no conflict with the previously used medicinal materials.
…
Doctors recorded symptoms while discussing pharmacology and medication possibilities!
After four hours, the potency of the medicine was basically exerted, and a dense list of symptoms and opinions was recorded on the piece of paper on one side.
Among the 20 people who participated in the initial clinical trial, 19 people's symptoms have been relieved.
As for the medicine used by the remaining person, it was the same as Chen Danlin. Among the ten medicines, the medicine was the most overbearing and violent, and his body could not bear it.
Although there is no immediate danger of life, the sequelae are still left in the lungs and require long-term care.
It was still noon when everyone entered the ward, but the moon and stars were already dimmed!
…
"Hahaha, it's done! It's done!"
The next day, Sun Shichang's hearty laughter came from another ward. This laughter seemed to be contagious, and the laughter in the room became louder and louder!
The new medicine is ready!
After the first trial, Sun Shichang summarized the dosage of these ten medicines, and after discussing with Tang Shenwei and Li Binhu, he added Datura flowers, castor beans and other medicinal materials.
Yesterday, the second batch of patients who drank the decoction were in good condition after the effect of the medicine took effect overnight.
Sun Shichang felt the pulse of the patient who had taken the medicine. Under the expectation of everyone, he put the patient's hand back on the quilt, stood up and said with a smile: "The poison has been eliminated, and only the symptoms of the epidemic remain. I only need to take the medicine for two more days, and there will be no more symptoms."
The disease can be cured!"
The laughter in Jinling's yamen spread as the news spread. The sky above the yamen was full of cheerful sounds.
The antidote is ready, and the epidemic must be over!
-----------------------
"Jinling Eight Hundred Miles is urgent! Everyone, get out of the way!"
A fast horse flew into the capital of the gods, and Yang Qingyuan's memorial arrived! But it was not an ordinary memorial, but a secret memorial directly addressed to the emperor.
It was already Xu hour at night, and the palace door was about to be locked. However, the emperor specially ordered to present this secret document.
Jinling was sealed off by Yang Qingyuan, and no new news had been received in the past ten days. The central government officials were quarreling over this matter.
Those demons and monsters kept popping up, asking Emperor Linde to issue edicts to repent for his sins. Some people criticized Yang Qingyuan, Wang Hua and others, wanting to depose Yang, Wang, Li and Yao and seize power.
The arrival of this secret discount obviously made the entire capital unable to sleep well at night!
After Emperor Linde confirmed that the wax seal was intact, he opened it and unfolded the paper inside.
There are only a few lines of words on the paper.
"The epidemic in Jinling has been resolved, and there is no obstruction in the south of the Yangtze River. There is no need to worry. This is a good opportunity. I hope you can make good use of it! The word Qingyuan!"
When he saw these few lines of fine print, Emperor Linde was much calmer in recent years than in the past, but he still couldn't help but be excited.
Master is still the same Master,
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The pillar of the country!
"Epidemic" has been an unparalleled disaster for all ages.
Floods and earthquakes can be put aside before epidemics.
I didn’t expect Master to actually do it!
Although there is no detailed data on the paper, Shisan knows his master and there are no large-scale deaths in Jinling. This is enough!
Then, Thirteen turned his attention to the last few words of Yang Qingyuan.
This is a good opportunity, hope you make good use of it!
What a good opportunity, naturally it is a good opportunity to clean up the court.
After all, he had been on the throne for less than three years. It was naturally impossible to completely eliminate the malaise in the court, but now Yang Qingyuan created an opportunity for him and Wang Hua.
That night, Thirteen summoned Wang Hua to the palace to discuss matters.
That night in Shendu, I don’t know how many people didn’t sleep well.
The next morning, Emperor Linde was listless at the court meeting. Although he tried his best to keep his face normal, these old foxes who had been in officialdom for many years could see the caution, uneasiness and worry hidden under his face.
As for Wang Hua, the Grand Bachelor of the Cabinet and the de facto leader of the Cabinet Hall, although his face was as smooth as ever and without any disturbance, he could still see the bloodshot eyes and the looming fatigue on his face.
Seeing this scene, many people already felt confident!
Last night, they tried their best to find out about the secret report coming from Jinling, but they didn't get any results.
I just know that after reading the secret report, Emperor Linde announced overnight that Wang Hua, the great scholar of Wenhua Palace, Li Xunhuan, the right censor of the Imperial Procuratorate, and others came to the palace to meet the emperor.
These people are all the backbone of the new party.
From this it can be seen that the information in this secret report must be of great importance, and it is either good or bad.
Looking at today's situation, the answer is obvious!