Huang Jiacai reported a lot, but Yang Ping actually didn't listen at all. His mind was not on these things now, but on his own topic.
Anyway, Yang Ping felt at ease when Huang Jiacai was doing things. After he finished his report, Yang Ping just nodded symbolically.
After Huang Jiacai left, Yang Ping began to think about his research topic again. Brian was very successful in immunology. In the field of immunology, some of Brian's laboratory methods are definitely the most advanced in the world. Yang Ping
During this period of time, I communicated with him intentionally or unintentionally, and learned a lot about immunology. This knowledge is very meaningful to my own scientific research. Some of it can even directly replace the original laboratory methods and improve the efficiency of experiments.
Yang Ping’s current research on tumors will definitely apply his knowledge of immunology, because after the M13 phage is modified, it must not provoke the immune system, otherwise all previous efforts will be wasted, and a lot of immunology is involved when labeling tumor cells.
knowledge, such as knowledge about antigens. The study of tumor treatment must not avoid immunology. Now that there is such a big expert here, Yang Ping will definitely squeeze out his knowledge.
The transformation of the M13 phage includes several parts: transplanting the K factor onto the M13 phage, and then looking for a molecule that can pair with a certain marker substance on the surface of tumor cells, and using this pair of molecules for positioning, recognition and coupling.
Equivalent to missile navigation, the modified M13 phage must also have its own navigation system that can identify and connect to the tumor system.
The whole process is very complicated and involves knowledge about targeted therapy, but these difficulties are not difficult for Yang Ping. Even if there is no system, let alone the system, Yang Ping will face the difficulties.
Yang Ping took this time to enter the system and start preparing for experiments. However, after entering, the system space was empty and everything was there. What was going on? Why was there only one space? The previous system panels, equipment, and experimental subjects were all gone.
.
When Yang Ping was confused, a series of words appeared in the air: The system entered the dormant period, and the dormant time is not limited to test the real knowledge and skills mastered by the host.
What is going on?
Yang Ping has read a lot of online novels before, and he is not said to be well-informed, but he knows a little bit about it. He has never heard that the system will go on strike. It is also called to detect whether the host has used the system to learn real things.
Knowledge and skills.
Is this a test during the period of time when you have installed the system? See if you have made good use of the system?
"The countdown to system space shrinkage begins, 10-9-8-"
Before Yang Ping could react, the system space began to shrink, getting smaller and smaller, until it completely shrank to a point, and Yang Ping was forced to come out of the system space.
Damn it, the system is still here, which means that now I don’t have the system to use, and I don’t know how long it will be. Fortunately, I am still diligent. Since I got the system, I have been soaking in the system almost day and night, converting it into
I have read all the books many times, and I have used all the functions of the system that should be used. I am squeezing the value of the system almost all the time. I don’t know if it is over-development and the system is overwhelmed. Now I need to take a rest.
Although the system's dormancy was a bit unexpected, Yang Ping didn't feel too sad because Yang Ping had already made plans for the system's departure from the first day he got the system, so the temporary leave of the system now has little impact on him.
At least the psychological impact was not great. He only regarded the system as a tool from beginning to end and did not rely absolutely on the system.
Although there is no system available for the time being, Yang Ping's work is still carried out normally.
He first started studying the transformation plan of the M13 phage with paper and pen in his office. He drew an image of the M13 phage, and then expressed its structure completely and clearly, marking all the parts that can be disassembled and assembled by biology. Then.
Looking at this painting, Yang Ping thought about where to assemble the K factor and the navigation factor.
Yang Ping found that the training in the system during this period of time allowed him to exercise his thinking, memory and concentration, and became very powerful. In fact, the system space not only allowed him to learn knowledge, but also allowed him to hone his abilities. He tried
Several plans were developed to assemble K factor assembly and navigation factors on M13 phage.
This step is not difficult for Yang Ping. K factor, which is the tumor-killing factor, is now readily available, and the results in in vitro experiments are very good. However, there is currently no suitable substance for the navigation factor, which is the difficulty this time.
How to make this missile accurately attack tumor cells, Yang Ping needs to obtain a large amount of target information about tumor cells. Lu Xiaolu has already studied this topic in the laboratory and has collected some of this information.
After figuring out the target of the tumor cells, then contact the target to study the navigation factors, because they are a pair that must interact. The navigation factors must rely on the target to identify the tumor cells. Once the recognition is completed, the M13 phage binds to the tumor cells.
, inject K factor into tumor cells to start the apoptosis program of tumor cells and complete the hunting of tumor cells.
Without the opportunity for trial and error in the system space, Yang Ping could only start in-depth research on the targets by himself, hoping to summarize a set of theories to screen the targets, which would save a lot of time and reduce the number of trials and errors.
Yang Ping was used to closing his eyes and resting his mind. He leaned on the back of the chair with his eyes closed, immersed in his own thinking, and used his wild imagination.
How to make the modified M13 phage find tumor cells? Different tumor cells have both similarities and obvious differences. Therefore, in the future, M13 phage must be personalized for different tumor cells so that it can target one or
A type of tumor cells has affinity.
Just like the hepatitis B virus has strong selectivity for stem cells, how can the modified M13 phage recognize the current experimental tumor cells---Sisi's tumor cells.
Someone knocked on the door, and Yang Ping came back from his thoughts: "Come in!"
The person who came in was Song Zimo: "I heard that Mr. Zhang is in severe pain all over his body. Do you want to go see him?"
"Are the symptoms serious?" Yang Ping was worried.
Song Zimo said: "It must be serious. I heard that I really can't hold it anymore. Fatty Liang, Zhang Lin, and Xiao Wu just went to Zhang's house. They were all in a hurry when they went."
"These guys came to see how Mr. Zhang was acting alone and didn't say anything to us." Song Zimo felt strange.
''Yes, why don't I have any news at all?" Yang Ping looked at his mobile phone and saw that it still had battery power.
A graduate student outside the door was walking quickly with his bag on his back. Song Zimo stopped him: "Where are you going?"
"Shall I go to Zhang's home?" the graduate student said.
"What's wrong with Mr. Zhang? What's going on when I heard Zhang Lin calling and saying that he really couldn't hold on any longer?" Song Zimo asked.
The graduate student immediately said: "Oh, he hasn't played a game of chicken for several days. He really can't hold it anymore, so he asked a few buddies to go to his house and let's have a big fight today---"