The Nandu Affiliated rabies virus patient is still in a coma, but this is an active and controlled coma, that is, hibernation therapy. It can stop the brain from working and avoid the impact of hypoxia on brain cells caused by complications. Just like active
Place a fresh piece of meat in the refrigerator to avoid damage caused by hot weather.
After several days of treatment, there was no change in the rabies virus antibody titer, but Yang Ping is not in a hurry now and can only wait patiently for the disease to reach an inflection point. His new plan can only protect the brain from damage, and the body itself must be relied on to deal with the rabies virus.
immune system.
For this patient, the leader of the National Health Commission called Professor Su almost every day to understand the changes in the patient's condition. He knew that the final outcome would not change, but he still hoped for some miracle. Once this young scientist had an accident, the country would
An important national defense project is about to be delayed, and the leaders are confused as to why they have suffered from this hopeless disease.
Without vaccination, once rabies attacks, the mortality rate is 100%. The leader is also a medical expert and understands this truth very well.
But when they heard about the new treatment method that Yang Ping was using, the leaders of the Health Commission suddenly brightened up. This young man was the seed player in everyone's minds. He had a new method, which meant that there was still a glimmer of hope for this patient.
Immediately the leader of the Health Commission became happy: "Lao Su, if you really save this person, I will give you a great credit. In the future, you will have the green light to do things here. Of course, you must do things that I can do and do not violate any laws."
in principle."
Lao Su also seized this rare opportunity: "As you said, don't default on your debt then."
This leader and Professor Su are good friends and have a very good relationship, so the two of them chatted relatively easily.
In fact, Professor Su knows very well that there is no risk in using the new method in this case from any angle, so he strongly encourages Yang Ping to use it. What are the concerns about a case with 100% mortality rate? Since there is a glimmer of hope, he will go all out.
that is.
To put it bluntly, you have merit for rescuing someone. If you don’t, there is nothing wrong with it, because it is the same without using new methods.
The leader of the health committee had just made a call, and a call from Dean Liu from 301 came right after him. Dean Liu knew that Yang Ping was leading the treatment, so there was nothing to say. If he couldn't do it, then there was nothing he could do.
Dean Liu also sent experts, but they were just going through the motions and showing an attitude. With Yang Ping there, who would dare to give guidance.
The leaders on both sides had just finished making phone calls. Professor Su's cell phone was hot. Leaders from the General Logistics Department and the Science and Technology Commission also called. One of the leaders was Mr. Su from his family.
Because this young scientist was so important, Su Laosi decided to go and see it in person, and also to see his niece and son-in-law. He had never seen it before from what the second brother said about it.
Su Qinghe had heard about this niece-in-law many times, but had never met him. This time he happened to meet.
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Yang Ping will participate in the daily treatment summary meeting. Not only experts from the First Affiliated Hospital of Nandu University will participate, but experts from several other hospitals outside the hospital will also participate through video networking, including Xiehe, 301, Huaxi, etc.
To sum up now, the doctor had no problem in diagnosis and discovered the condition very early.
Everyone is now looking back at this patient. The patient's name is Chang Qirui, a 39-year-old male. The patient occasionally experienced numbness and tingling pain in his right hand on the second day after he went home to visit relatives. At that time, he did not pay attention to it, thinking it was just an attack of cervical spondylosis.
I took a pill of diclofenac sodium for analgesia. On the third day, I had a double image in front of my eyes. On the fourth day, I developed dizziness, nausea and vomiting. At this time, the patient realized that something was wrong and immediately told his colleagues about his discomfort.
There was a health care doctor accompanying him, but he was a general practitioner. He immediately arranged for Professor Chang to come to the Emergency Department of Nandu Affiliated One for treatment. Professor Su personally arranged the entire diagnosis and treatment process at that time, and the Emergency Department of Affiliated One immediately gave him an MRI examination.
No abnormalities were found. On the day of treatment, the patient's condition worsened: she suddenly developed a high fever and could not move the right half of her body.
This was a big deal, so the patient was immediately hospitalized. Where should he live? In order to facilitate treatment, he was directly admitted to the ICU. The neurologist who first consulted, Director Qi of the Department of Neurology, found that the patient had tremors and paralysis on the right side of his body during the consultation. He immediately
The patient's cerebrospinal fluid routine and biochemistry showed that he was infected by a certain virus, but all virus test results were reported to be negative.
This put Director Qi in a bit of a dilemma. In order to combine the power of the First Affiliated Hospital, Professor Su immediately arranged for an emergency consultation with Director Yuan from the Department of Infectious Diseases. When Director Yuan came, the patient's mouth was already bubbling.
Due to the popularization of rabies vaccine, the number of rabies cases per year is actually very small. Now there are only more than 100 cases per year. More than 100 cases are spread evenly across China, and there are only a few cases in one province, which can be said to be very few.
But Appendix 1 is Appendix 1. After thinking about it for a while, Director Yuan of the Department of Infectious Diseases immediately realized something was wrong: extremely atypical neurological symptoms, drooling, fever, and viral infection.
Then a disease --- rabies -- popped into his mind. He immediately contacted the patient's family and asked if the patient had ever been bitten by dogs, cats or other animals.
The family members were also confused at the time, but her wife said that she heard the patient mention that she was bitten by a wild dog when she and her roommate were hiking in the mountains when they just graduated from Ph.D. The injury was not serious at the time, just a little scratch on the skin, so at that time
I didn't take it seriously and didn't get vaccinated.
When Director Yuan heard this medical history, he was almost certain that the patient had rabies.
Soon, the laboratory department of the First Affiliated Hospital found rabies virus antibodies in the patient's cerebrospinal fluid and blood, and rabies was confirmed.
In fact, following this line of sight, the diagnosis was very timely without any delay, and the treatment was also very timely. As soon as he arrived at Annex 1, he was admitted to the ICU for symptomatic treatment.
Rabies scares doctors because of its 100% mortality rate. Its incubation period can be as short as a week or as long as ten years. When the disease occurs, patients will be extremely excited, sometimes violent, and have specific hydrophobia.
Director Yuan of the Department of Infectious Diseases reviewed the patient's diagnosis and treatment process. There were no problems. Now it is how to treat.
How to treat it is now introduced by Yang Ping. Everyone is still very familiar with Yang Ping. In the medical field, it is now a legendary demigod. Anyway, it is becoming more and more popular, especially among young doctors. It is like talking about anime.
Looking at the experts at the table, Yang Ping also said very truthfully: "The method I proposed is neither random nor out of the ordinary, but has a sufficient theoretical basis. Since the cause of death from rabies is damage to the nervous system,
Cause, why can’t we seize this point and protect the nervous system. Use drugs to put the brain into a low energy consumption state.
This can effectively reduce the occurrence of rabies complications in the brain and reduce damage to the nervous system. At the same time, the patient's immune system continues to operate. If during this period, the patient's immune system can produce enough anti-rabies antibodies,
It can eliminate the virus, that is to say, let the patient suspended animation to engage in an immune race that deceives the virus."
"The target of rabies virus is the brain. This is usually the case. When the rabies virus invades the human body, the immune system fights bravely against it. After fighting and fighting, the virus decapitates the brain, the general, and the war is naturally lost. In fact, if
The general will not be beheaded so quickly. It is still possible for the immune system to eliminate the virus, so we come up with a strategy to hide the general as soon as the war starts.
Come, announce that the general has died in battle, so the virus that is good at beheading is no longer available. It can only continue to fight against the immune system. As long as it is given enough time, the immune system may eliminate the rabies virus. The immune system could not before.
The main reason for eradicating rabies virus is that there is not enough time, or even if we gain the upper hand, the general will always be beheaded in the end, and we have to declare failure."
It's easy to understand in this way, and the meeting doesn't seem so rigid. Since it's a new plan, everyone can discuss it in a relaxed manner.
Director Yuan has also been thinking about this method these days. It is indeed very creative, but he just put the theory into practice without going through animal experiments and clinical experiments. However, this is also a special case. Since it is a 100% mortality rate, that is
To use new methods is to strive for breakthroughs, and the worst thing is to maintain the status quo - 100% mortality rate.
If supporting Yang Ping before was because of Professor Su's face and Yang Ping's reputation, now after thinking about it for a few days, I am convinced. Regardless of whether this method is effective or not, at least it has made a breakthrough in theory. It has not been in the original circle.
Round and round.
The original method definitely won't work. It's just that nothing new has come out, so we can only remain conservative for the time being. If it works, it won't have a 100% mortality rate. In fact, the original method has no method.
"Professor Yang, I have been thinking about it for so many days, and what you said does make sense. In the words of you young people, it is indeed very imaginative. Although I have not done any experiments, I think there is a certain success rate." Director Yuan
He's not flattering, he's telling the truth.
Director Luo of the ICU said: "I think so. Some things can be judged theoretically. Even without experiments, we are somewhat sure. I just listened to Professor Yang's explanation. I didn't understand it at first.
Is there any new method for treating this disease? I just thought of it on the spur of the moment.
But after listening to it, I felt quite touched. It is true that some things can be understood without experimentation. This new method has really given me some insights. In fact, we have always done this for many things, regardless of whether the effect is good or not, and we have not reflected on it.
Even come up with some ways to improve the effect.”
Everyone is telling the truth. Most of our work is usually repetitive, and we rarely think about innovation. After all, innovation comes at a cost, and it is difficult for people without a certain degree of curiosity to have the motivation to innovate.
During the discussion, a doctoral student came in and said that the latest virus antibody titer had increased.
Is it elevated? That means the condition has reached an inflection point, which means that the immune system has a great chance of eliminating the rabies virus. Yang Ping feels a little more confident.
At this meeting, not only senior experts participated in the discussion, but also gave young doctors the opportunity to participate in the discussion. Everyone felt a sense of intimacy when they saw Yang Ping, and they were bold when speaking. After all, they are all young people, and these doctors will all
He regards him as one of his own.
After the meeting, Yang Ping was about to go home. Professor Su immediately called and told Yang Ping to go to his office as soon as possible.
Why are you going to the office? My father-in-law is too busy today. He brought me a lunch box and asked him to go there to eat. My father-in-law will not leave me to eat every time in the future. Yang Ping was walking to Professor Su's office muttering.
Seeing several guards in military uniforms in the corridor, he reported his name and the guards immediately took him to Professor Su's office.
Yang Ping was confused as to why there were still guards guarding Professor Su's office.
Knocking on the door and going in, I saw a mighty man in military uniform sitting inside. He looked very similar to his father-in-law. The flowers on his shoulders were of general rank.
"Why don't you come in quickly and call Uncle Fourth!"
"Uncle Four!"
Yang Ping shouted quickly.
The general stood up and patted Yang Ping on the shoulder: "You are Yang Ping. If you hear his voice before you meet him, you are very famous."
Yang Ping didn't even know how to reply.
"He's just a silly boy who only knows how to giggle and doesn't sit down and chat with his fourth uncle." Professor Su said lovingly.
Fourth uncle? Where is the fourth uncle? Oh, Yang Ping remembered. Of the four brothers of Professor Su, this fourth uncle has never been seen before. The other three were seen at Su Nanchen’s birthday party. I just heard Xiao Su say that this
My fourth uncle is in the army.
"He performed operations on several of my old leaders. He is very famous." Su Qinghe smiled heartily.
Yang Ping blushed, and Professor Su said: "Young people only know how to do surgery, but they can't speak. Don't mind, fourth child."
"Second brother, you have such vicious eyes. This young man is not an ordinary person. He is the youngest expert in the health care team. Several of my old leaders are full of praise for him. I finally met him in person today."
"Professor Yang!"
"Call me Xiao Yang!"
"Look, you are so humble. My old leader always calls you Professor Yang, and I call you Xiao Yang. If you meet the old leader one day, you will definitely be criticized." Su Qinghe joked.
"You can call him Xiao Yang if you are a member of your family." Professor Su said with a smile.
Su Qinghe thought for a while and said: "Okay, Xiao Yang, Professor Chang Qirui is now in charge of a very important project. Once something happens to him, the success of this project is likely to be delayed for 5-10 years. We did not expect that there would be an unexpected incident."
Regarding this kind of thing, I just heard your dad say that rabies has a 100% mortality rate. This is a fact that cannot be changed. But I heard that you are using a new method to treat it. Please tell me what you think about it.
How certain I am, how certain I am, I just want to understand the situation."
"Because this method has never been used before, it's hard to say, but judging from the current changes in the condition, there is still hope, and it will not be said to be 100% fatal." Yang Ping replied.
The latest test report just now shows that the rabies virus antibody titer has increased, which means that there is a certain success rate, which is quite high.
PS: I'm a bit busy today, so I may not have revised it carefully. If there are any problems, I'll revise it tomorrow, thank you!