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Chapter 594 Strange renal bone disease

In the space laboratory, Yang Ping used experimental subjects to observe the pathogenesis of teratoma.

How these cells develop into various organs in the human body, such as teeth and hair, is also reported in the top international magazine CELL. A research team from the University of California has used teratoma as an ideal model to study the human development process.

Teratomas are tumors that contain a variety of tissues, including bone, brain, hair, and muscle.

Its formation is caused by the uncontrolled differentiation of a large number of stem cells and can occur in all types of tissues in the body. It is another possibility besides the fetus that human tissues and organs can be assembled by cell division.

Therefore, this control of stem cells is of great research value.

The laboratory in the system space is very quiet. There is only Yang Ping. His assistant is a mechanical arm like a mechanical octopus's tentacles. Various equipment is placed in an orderly manner.

These equipments are all top-notch in the world, such as electron microscopes, gene sequencers, etc.

From the experimental body purchased from the mall, Yang Ping took out some tissues and observed them under an electron microscope.

How they differentiate into muscles, and how the human body regulates their differentiation, involves too much information, which is far beyond the technology of spinal external fixators.

Engaging in scientific research is a lonely and lonely thing. If you don't have a strong interest, it will be difficult to adapt.

Here, the laboratory is isolated from the outside world and cannot access the Internet. The only alternative to the Internet is the system library, where various books and periodicals can be accessed at any time.

Yang Ping is like a prisoner, locked in space.

He not only observed changes in various cell structures, but also sequenced genes, hoping to decipher the mechanism of organ formation and to grow organs in vitro.

It's a pity that you will be mentally exhausted if you stay in there for a long time, and you need to go out for a while before you can continue. Otherwise, you can stay in and complete the experiment successfully before going out.

When Yang Ping came out, everyone had already finished get off work.

August kept one apple for himself and distributed the rest to other doctors and nurses.

During this time, he just wanted to study hard with Professor Yang without any interference.

He likes his current learning state very much and is making progress every day.

---

Dormitory for trainees of Sanbo Hospital.

August shut himself in his room and was writing an e-mail to the Duke. Foreigners like e-mail.

"Hello, Mr. Duke, I have been in China for nine days and have seen with my own eyes the novel effects of Professor Yang's new technology. It is suitable for almost any spinal correction and is very safe. The gradual and gentle correction allows the soft tissue to fully adapt.

Time, so in today's world, if we want to save the little Duke, this technology must be the only one. Just yesterday, Professor Yang discussed the little Duke's condition with me, and we have agreed to go to Germany to operate on the little Duke, but the obstacle now is the new equipment

It has not yet obtained legal permission for use in Germany, so our Harlachen Orthopedic Hospital must secure a clinical trial base so that the new device can obtain legal permission as soon as possible---"

After writing the email, revising it several times, August sent the email.

Then I wrote a diary again.

[Today, the professor came to talk to me about the little Duke’s condition. I was very happy because this was the first time that the professor came to me to discuss the case alone. I originally thought I could drink the professor’s cup of tea, but I didn’t get it. I have done it before

Hint, deliberately showing that my throat is dry, but the professor did not see it, or he saw it, and would not give me a cup of tea for this reason. This cup of tea represents strength and honor. During my further studies, I will definitely get this cup of tea.

Come on, August, you can do it!】

August came out of the room, Robert and Takahashi were watching TV in the living room. TV can not only learn Chinese, but also understand Chinese culture, so they must watch TV for an hour every day.

The three of them sat down, watched TV, and exchanged their learning experiences. August's impression of the Japanese changed somewhat.

In fact, the focus of their studies is different. August specializes in spinal surgery, so he must study and master the entire technology in depth.

In the future, Takahashi will become an all-rounder in orthopedics at Tokyo University Affiliated Hospital. Like August, he needs to master new technologies, but he does not have the urgent need for in-depth research like August.

Robert's main direction is sports medicine. He only needs to understand spinal surgery. He hopes that the concept of this technology can be used in sports medicine in the future. At the same time, he represents the hospital to fight for a clinical trial base for new technologies.

"Bang bang bang!" Someone knocked on the door.

August happened to be free, so he opened the door. It was the Chinese training doctor next door.

The Chinese trainee mysteriously told August some bad news. A girl had lost her underwear in the dormitory where the interns were. She had reported it to the hospital security department and hoped that everyone who saw the suspicious person would contact the dormitory management.

August frowned and turned to look at Takahashi.

Could it be?

It's him!

---

In the afternoon of the next day, Yang Ping went to the ICU to see Li Jun, accompanied by Song Zimo.

Because Li Jun is in the ICU ward, Yang Ping has to go to the ICU at least once a day.

Sanbo Hospital has three ICUs, a general ICU, a trauma ICU, and a CCU, which is a cardiac intensive care unit.

Qin Xiaowei has been away for a few days and has not appeared again, but according to the doctor, he will call Dr. An every day to inquire about Li Jun's condition.

"We recently did another electroencephalogram on him, and his brain waves were much more active than before."

The director of the ICU went out for consultation, and Dr. An accompanied Yang Ping to report on the latest progress of the condition.

Brain waves are more active, which often means waking up is imminent.

Dr. An asked someone to bring over the electroencephalogram and show it to Yang Ping.

Indeed, brain waves are much more active.

Yang Ping carefully analyzed the brain wave images and Li Jun should wake up soon.

It seems that he is very lucky. If he can wake up, he will have passed one of the two hells.

The remaining one is about to leave ECMO at the last possible moment.

"For renal anemia, we inject Aridrzo (roxadustat) through the stomach tube for a period of time, and the red blood cell count and hemoglobin content tend to increase. We are still looking for the optimal dose of anticoagulant drugs. This dose is difficult to control.

Even if we master it now, he will still have to face this problem in the future."

This chapter is not finished yet, please click on the next page to continue reading the exciting content! Dr. An checked whether the various ECMO channels are smooth and whether the parameter settings are reasonable.

"Director Liu from the Kidney Transplant Center is here!" Dr. An revealed new information.

Yang Ping was shocked. Tan Xiaowei talked to him before leaving and revealed that he was leaving for a few days to prepare for free-hand rock climbing. Free-hand rock climbing is very dangerous. Although he was very confident, he had to prepare for the worst.

If something goes wrong with him, donate one kidney to Li Jun and give the other kidney to someone in need.

If he can come back safely, as long as Li Jun can survive the danger and has the conditions to undergo a kidney transplant, he hopes to transplant a kidney to Li Jun as soon as possible.

Director Liu from the Kidney Transplant Center came over, probably to check on Li Jun's condition. In this state, life or death is pending, and it is impossible to perform a kidney transplant operation.

"I heard from the doctor at the kidney transplant center that his cousin's kidney is a good match for him. If he can get through this ordeal, it would be a good thing to get a kidney transplant," Song Zimo said beside him.

Dr. An nodded, feeling a little more confident.

After looking at Li Jun, Yang Ping subconsciously glanced at the ward next to him. The person had changed. Now there was a fat man lying there. He was so fat that his body could take up the entire bed.

This reminded Yang Ping of the patient he met before, Wei Danian.

Yang Ping still remembered the patient's name because he suffered from a rare genetic disease and often suffered from lactic acidosis. Later, Yang Ping contacted the genetics laboratory of Nandu Medical University and found through gene sequencing that this guy had a mutation in the ATP5F1D gene, and this

The gene is involved in mitochondrial function, causing lactate metabolism disorders.

Although there was no solution for the time being, Dr. Jin drew him a calendar of disease patterns to help him avoid risks.

"What's that patient's name? What's his condition?"

Yang Ping pointed to the next door and asked Dr. An curiously.

"Wei Danian, lactic acidosis! It seems you were the one who diagnosed it last time?"

It’s him again? Wei Danian weighing 400 pounds.

Yang Ping felt that this guy was really lucky. He always had a 50% chance of survival and was always caught by him. Every time he tossed a coin, he always got what he wanted.

"Is the person awake?" Yang Ping wanted to talk to him.

"Awake, prepare to be transferred back to the endocrinology department tomorrow." Dr. An took Yang Ping to the ward.

Wei Danian, Yang Ping must go and see. This patient made several doctors' names appear in the top magazine - "New England Journal of Medicine", and Wei Danian's name was used to name this disease.

"Wei Danian!"

Yang Ping called his name.

This 400-pound young man stared at Yang Ping with narrowed eyes and didn't react for a long time.

Wearing a mask and hat, Wei Danian couldn't recognize Yang Ping.

"Doctor Yang, I performed surgery on your broken thigh!" Yang Ping reminded him.

He squinted his eyes and thought for more than ten seconds, then smiled stupidly: "You are Dr. Yang, the one who helped me operate and set my bones. Why are you here? What a coincidence!"

Nonsense, I am a doctor here, is it weird to meet me?

Looking at this, Wei Danian has gained some weight. He could still open his eyes before, but now he opened them hard and only a crack was exposed.

In the past, the neck and shoulders could be distinguished, but now the neck and shoulders cannot be distinguished.

If you don't do anything about this weight, it will be a big trouble in the future.

"I only remember Dr. Jin, I almost forgot you, Dr. Yang, sit down! You're welcome!" Wei Da got out of bed to greet the guests.

Doctor An was so frightened that he quickly held him down: "Don't move!"

"You're welcome, we can just stand."

Seeing him like this, Yang Ping was confused and thought he was at home.

Chat with Wei Danian for a while.

This time he clamored to go on a trip. As soon as his father checked the life calendar that Dr. Jin gave them, several red dates were coming soon. Going on a trip was not asking for death. Not every time he would have such good luck.

Under the persuasion of his parents, Wei Danian had no choice but to cancel the trip and stay in an endocrinology department to prevent an outbreak of lactic acidosis.

As a result, lactic acidosis broke out just after he was admitted to the endocrinology department. Wei Danian fell into a coma and was sent to the ICU for rescue.

Wei Danian's home is on the first floor of the community opposite the hospital, close to the gate of the community facing the hospital.

For no other reason than that the ambulance can arrive in a few minutes.

With this calendar, Wei Danian's parents learned a lesson. When the red days come, they simply go to the hospital on those days. In case of illness, there are doctors and nurses, and the probability of successful rescue is high. You can't always gamble on luck.

After coming out of the ICU, I met Wei Danian's parents in the family waiting area.

The father, who is also a fat man, recognized Yang Ping and was grateful to Yang Ping. If Yang Ping had not helped with gene sequencing to find out the cause of lactic acidosis, and later Dr. Jin drew up a life calendar, his son might have died again this time.

It's dangerous.

Now that we have a calendar, when encountering high-risk days, we can go directly to the hospital to wait for the onset of illness, or we can take measures to intervene in advance to avoid falling into danger.

---

After returning from the ICU, Yang Ping went to participate in a hospital-wide case discussion. Over there in the internal medicine building, the medical office organized a meeting. Once a week, the whole hospital brought out some difficult cases for everyone to discuss and brainstorm. This is Sanbo Hospital

old tradition.

When Yang Ping arrived, many people had gathered.

Professor Zhang Zongshun was also there, as well as the directors of various subjects, a lot of doctors and masters.

He arrived a little late and there was no seat. Professor Zhang waved and asked Yang Ping to come over. It turned out that there was a seat beside him.

The cases in this consultation are a bit interesting.

A patient in the otolaryngology department had a dental implant before and had been experiencing pain in the left sinus. When an X-ray was taken, the screw that fixed the denture was missing in broad daylight. There was an image of a screw in the left sinus. The screw had gone into the sinus?

How it got there, no one can figure out.

The final result of the discussion: open the sinuses and remove the screws.

A patient in the Department of Urology had a persistent erection after a cold. Various drug treatments were ineffective. When the patient was finally ready for bloodletting, the anesthesiology department helped solve the problem with spinal anesthesia, but the patient could not always bring an anesthesia pump.

A six-year-old patient in the pediatric department has a high fever every Tuesday afternoon for no reason. It has been like this every week for the past three months. All examinations found nothing abnormal.

Let the experts study and find out what is going on.

A patient in the Department of Nephrology, also a uremic patient, started receiving hemodialysis 7 years ago due to renal failure. Later, he felt bone pain all over his body, which became more and more severe. He gradually developed joint deformities, blurred vision, tooth loss, subcutaneous induration, etc.

symptom.

I had kidney stones for more than ten years and had to remove the stones eight times. Finally, I needed hemodialysis because of kidney failure caused by the kidney stones.

There are several kidney stone patients in the family, one of whom died at the age of ten due to uremia caused by kidney stones.

The physical examination revealed that the patient had decreased vision, multiple missing teeth, hard nodules and pigmentation on the skin of the limbs, deformed fingernails, interdigital joints, interdigital joints, bilateral ankle joints, knee joints, elbow joints, and shoulder joints.

All showed enlargement and deformity. Slit lamp examination revealed calcium salt deposition around the cornea of ​​the left eye. Abdominal CT showed nephrocalcinosis in both kidneys. Under

Calcification of terminal soft tissues.

Nephrology considers renal bone disease.

But this renal bone disease is a bit interesting. How can there be calcium salt deposition in the cornea?

This week's case discussions are very valuable, as they are all difficult and complicated diseases. As soon as the cases are presented, everyone gets a headache.

Yang Ping is very interested in this strange renal bone disease.

This was obviously not renal bone disease. Yang Ping sorted out the patient's medical records in his mind, stringing together the medical history, physical examination and auxiliary examinations with logical clues as much as possible.

In medicine, diagnosis is based on monism. If a disease cannot be explained clearly, then two diseases are considered to coexist.

If one disease can explain all symptoms and signs, then try to use one disease to explain it.

PS: I finally finished editing it. I got off work very late today and this chapter was difficult to edit. It took me a long time to edit it. Thank you everyone!


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