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Chapter 613 Inducing Substances

Imperial Union Medical College Hospital.

Professor Liang is sitting in his office chair, with his glasses placed on the table in front of him. He is listening to Professor Hu Guolin's report on the arrangements for the second phase of clinical trials of spinal external fixators.

"Very good, if necessary, please invite Yang Ping to demonstrate the operation. After all, it is a new technology. We are only theoretically mastering it now. It would be better to observe a few operations. In addition, 301 has taken action and given Yang Ping 10 beds.

Together with a supporting team, we regularly invite Yang Ping to 301 for surgery. This cooperation method is feasible and we can imitate it. In terms of case resources, especially special cases, we have more than 301. Let us also give Yang Ping 10 beds and equipment.

A team will assist him, with Song Yun as the team leader and a few doctorates at the attending level. Young people will feel more comfortable working together."

Professor Liang leaned back in his chair, squinted his eyes slightly, and pinched the bridge of his nose.

Professor Hu Guolin suggested on the side: "301 provides 10 beds. Can we increase the number of beds, preferably double them? It is much easier for us to increase the number of beds here than for them."

Professor Liang slowly shook his head and said: "No need to increase the number, don't engage in this kind of malicious competition. In the end, a rising tide will lift all boats and embarrass everyone. Invite Yang Ping to Xiehe Union through cooperation. We have the same purpose as 301, to care for talents.

Respecting talents, I have to admit that this young man is a rare genius. At least among the young people I have met, no one can compare with him. You see, this spinal external fixator, the animal experimental data at that time was so beautiful that I once

I thought there was something wrong with the data, but after checking it myself, I found out that there was no problem. It was really unexpected that such a new technology was developed in just a few months."

"I heard that there will be further actions from 301. It seems that they are not as simple as cooperation." Professor Hu Guolin was a little worried.

Professor Liang smiled and said: "Don't worry, if Yang Ping changes places, it would be better for him to come to us than to 301. Our place is more suitable for him, but I have thought about it for a long time. No matter whether he comes to us or to 301, it is not the best.

On the contrary, things will restrict his development. I am still thinking about what is the best way. Let's bring him into the health care team first. I met Qin Shi and Liu Xingguo and mentioned this matter. It is up to them to handle this matter.

"

"I have also stayed in Sanbo Hospital for a while, and I still know a lot about Yang Ping. This young man usually has nothing to say and always seems very profound. He rarely participates in any meetings held in the hospital. He just talks to others.

The assistant goes, anyway, he only cares about his own patients and their condition, and seems to have no interest in anything else. He feels that it is difficult for others to get along with him." Hu Guolin concluded.

Professor Liang disagreed with Professor Hu's words: "Geniuses, those who have no personality are geniuses just because they are different. If they are the same as everyone else, they are not geniuses. It is good that Sanbo Hospital has this, that is, tolerance. We

No one can be so tolerant."

"I agree. The director of Sanbo Hospital is also a very unique person. He and Han Jiangong gave Yang Ping the entire surgical authority. You are talking about a young doctor who has only worked for a few years and has not been regulated by other specialties.

If the training is given to other hospitals, it is impossible to give him so many surgical rights. What if someone loses his life?" Professor Hu Guolin has never understood why Sanbo Hospital is so bold.

At that time, during a scoliosis surgery, Yang Ping was asked to perform cardiopulmonary surgery at the same time as he was undergoing spinal surgery and was complicated by abnormal heart and lung adhesions.

This kind of interdisciplinary surgery would never happen in other hospitals. If anyone proposed such an idea, they would definitely be treated as a joke.

"This is the reason why he stayed in Sanbo. To be honest, I used to insist on introducing him, but later gave up the idea. As long as he does not go abroad and can stay in China, I will be satisfied. If he is really introduced to our hospital, he will be a good candidate in the Department of Orthopedics.

On the other hand, can I protect him, outside of my field, how can I protect him? Mu Xiu is bound to be destroyed by Lin Feng. His personality is suitable for academics, but it is easy to offend people. In Sanbo, there are

Xia Changjiang protects him, so this child can make a name for himself. But if we put it here, the foundation alone cannot handle it. So much money is directed to him alone for scientific research. Can everyone agree? Can the higher-ups agree? At the leadership level of the hospital.

Who dares to push this kind of thing like Xia Changjiang? If anything goes wrong, Xia Changjiang will not be able to live with it." Professor Liang was quite appreciative of Dean Xia.

"Well, it's true. When this foundation was established, Xia Changjiang put in a lot of effort. I heard that he went to the provincial department, civil affairs, and provincial government every day to lobby the big bosses from all parties to sign." Professor Hu Guolin knew about this matter.

"This child has a bright future and can make great achievements. Sanbo Hospital is a hospital directly under the provincial government, but it is still a bit thin and does not match his energy. I am wondering if I can promote the upgrade of Sanbo Hospital.

I haven't figured out how to upgrade yet, I have to discuss it with a few old leaders." Professor Liang seemed to be deep in thought.

"What happened to Hans last time almost destroyed the spinal external fixator. Sanbo Hospital alone cannot handle this kind of thing." Hu Guolin still had lingering fears.

Professor Liang's face darkened: "Huh! What can a company, even a multinational giant, do? Their behavior is against our entire medical community. It is polite not to kick them out. Fortunately, even if they

Adjust and finally surrender. If things escalate again, what if they are kicked out? If one of their companies is missing, the vacant market will be filled by someone immediately."

"I mean, this incident also exposed your old worries. Sanbo Hospital is too weak and does not match Yang Ping's ability. This is just an external spinal fixator. In the future, he will produce more valuable results. Wan

If you touch other people's cheese, you will get into trouble. This time you intervened in time, so you may not be so lucky next time." Professor Hu Guolin said what he was worried about.

This chapter is not over yet, please click on the next page to continue reading! Professor Liang nodded: "Yes, so I am thinking about how to upgrade Sanbo and make the platform larger and stronger so that he can use his skills.

"

"Mr. Liang, there is one more thing?"

Professor Hu was quite embarrassed.

"What's the matter?" Professor Liang asked.

Professor Hu rationalized and said: "Our hospital proposed to visit the MIT Baitou Bioenergy Research Institute, but the other party refused. Zhang Chunquan said that this project currently refuses outside visits, and there is nothing he can do. I heard that they have established an inducible

Universal stem cells have made the most groundbreaking progress in the mechanism of stem cell regeneration and differentiation and rearrangement, and are one step closer to cloning complete organs. The person who has made the greatest contribution to this project is actually Zhang Chunquan."

Professor Liang asked slowly: "Has Zhang Chunquan become an American citizen?"

"Yes!" Professor Hu whispered.

Professor Liang remained silent, feeling a sharp pain in his heart.

---

Before handing over, there was still a certain amount of time and others would not disturb him. Yang Ping was conducting experiments in the laboratory in the system space.

He often enters the system space to conduct experiments in the morning, noon and before going to bed. At this time, the system space is the most stable and stays in it for the longest time. Sometimes he also enters the system to conduct experiments while resting in the dressing room of the operating room. In short, he can use

He made use of all his time.

Yang Ping used teratoma experimental subjects purchased from the system mall as research subjects to observe how teratomas grow and develop. He used electron microscopes to observe the teratoma tissue cells at each stage to observe how they divide and differentiate step by step, and then used

The electron microscope takes continuous photos and arranges the photos in order.

Yang Ping also extracted body fluids and tissues for research on the surrounding environment where teratomas occur, grow and develop, to find out whether there are some inducing substances in the surrounding environment, and to find out what inducements the human body relies on when pluripotent stem cells differentiate.

, how to regulate induction, whether it is induction by a single method or by a combination of multiple methods.

This is a huge amount of work, but the transient rules of system space make time very cheap.

However, there is a psychological limit to the time you can stay in the system space. Yang Ping's current psychological limit is getting higher and higher, and the time he can stay in it is getting longer and longer.

Every time Yang Ping does an experiment, he tries to stay until the limit time before coming out, then rest in reality for a while, and then find a quiet time before going in again.

This kind of remission period set by the system space is like a man's sage time. After staying in the space for a period of time, he must come out to rest and spend the "sage time", and then go in again next time, and so on.

The psychological limit has been reached, and it is meaningless to forcibly extend the time. The already unstable psychological state cannot continue the experiment, and this forcible extension of time is also a kind of psychological damage.

But no matter what, compared to reality, time in system space is quite cheap.

Through this period of research, Yang Ping made some small breakthroughs.

He found that there are some "inducing substances" in the environment around teratomas. The substances that exist around different differentiated tissues of teratomas are different, but the substances that exist around the same differentiated tissues are the same.

For example, the biochemical substances distributed around the muscles and bones grown by teratomas are different but they are the same muscle tissue. Different experimental subjects have the same "inducing substances" around the muscle tissue of teratomas.

At present, Yang Ping only drew general conclusions from electron microscope observations. Whether they are the same requires structural analysis of these substances.

If it is really the same, it at least prompts a question: there is a batch of the same living substances around each differentiated tissue. Whether these substances have an inducing effect requires further research.

Yang Ping also observed a phenomenon that the distribution range of these substances coincides with the distribution range of the corresponding specific tissue cells. If they exceed the range, these substances will automatically be decomposed and eliminated.

How exactly it was done, Yang Ping didn't know yet.

Yang Ping concluded that these substances should be possible "inducing substances".

The next step is to extract these biochemical substances and then conduct structural analysis using cryo-electron microscopy.

The structure of each biochemical substance is analyzed one by one, and then accurately classified, and matched with the teratoma differentiated tissue to create a paired "induced substance spectrum".

Then according to the "inducing substance spectrum", some "inducing substances" are extracted from the experimental subjects to cultivate pluripotent stem cells. If the differentiation of pluripotent stem cells can proceed in the expected direction, then these biochemical substances can be determined to be inducing substances.

If it cannot differentiate according to the target cells, it means that in addition to the inducing substances, there are other inducing methods to induce differentiation, or these are not inducing substances at all.

This kind of work is extremely boring and cumbersome, and the workload is huge. In the laboratory of the system space, the mechanical assistant can only help with some unskilled work, that is, it replaces Yang Ping's hands, but cannot replace the work of sharing Yang Ping's brain, so a large number of

Yang Ping needs to do the work himself.

And sometimes the initial research direction is considered correct. When the research proceeds to a certain extent, it is discovered that the entire general direction is wrong. At this time, the entire project has to be overturned.

Therefore, a scientist sometimes only achieves a breakthrough after decades of research, while some may not achieve a breakthrough in his entire life.

In addition to inspiration, diligence, and accurate grasp of the research direction, scientific research also involves luck. Of course, luck is predicated on diligence. Without persistence for more than ten or decades, any luck will be in vain.

Just like there are millions of roads leading to the goal, only one is correct. When setting out, no one has more information to judge which one is correct. As we walk, some people finally reach the destination successfully, and some people find that they have gone halfway.

It's the wrong path, and some people realize they are wrong after walking this path, but no matter what, you must go on it to have a chance of success.

For basic research like this, it is very difficult to produce results, and the research cannot be profitable. Therefore, scientists are required to calm down and conduct research in a down-to-earth manner. At the same time, they are required to provide stable and good treatment for scientific talents in basic research. If they are eager for quick success and instant benefits, basic research will not be able to do so.

Get on with it.

Basic research is the most important part of the entire scientific research system, just like the cornerstone of a building. Without the support of basic research, no matter how prosperous applied research is, it will be like building high-rise buildings on the beach.

Yang Ping recorded his staged research results and left the system laboratory.

He browsed through the emails in his mailbox.

Auguste will report the little Duke's condition by email every day. His vital signs are stable, and no neurological symptoms have been found for the time being. After the operation, the magnetic resonance imaging showed no local signal changes in the spinal cord, indicating that there was no embolism in the spinal blood vessels, and there was no embolism in the surgical area.

The negative pressure drainage tube has been removed, the vicious cycle of the cardiovascular system has been corrected, the heart is getting better, and the amount of blood circulation shared by ECMO has gradually begun to be reduced, and we strive to slowly wean ourselves off the machine.

August compiled a list of scientific research projects funded by the Duke's Fund, and this list has been sent to Yang Ping.

Yang Ping printed it out, checked a few projects related to his topic, and planned to arrange time to conduct an inspection to see how far his colleagues in the world had gone, communicate with each other, learn from each other, and avoid working behind closed doors.

After completing these tasks, Yang Ping took a rest and waited for the next shift of ward rounds.

This is a trilogy of his work, day after day, year after year.


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