Chapter 878 Trial and error - the biggest cost of scientific research
Because there were many injured firefighters, even if they were dispersed to various hospitals, Sanbo Hospital had more than 20 firefighters assigned. All of them suffered blast injuries caused by the air wave of the explosion, and most of the injuries were to the lungs.
According to the priority of the condition, these more than 20 firefighters were dispersed to ICU, thoracic surgery, general surgery, orthopedics and other surgical wards.
The several firefighters who were admitted to the ICU were all members of Fang Liu's squadron. Because they were evacuated from the center of the fire source and the distance to evacuate was the furthest, when the explosion occurred, they were relatively closest to the explosion.
Naturally, the blast wave will do the most damage to them.
Except for a few firefighters who were admitted to the ICU who were under the responsibility of the Institute of Surgery, the other firefighters were not assigned to the Institute of Surgery for the time being. So Director Fang and Director Gao had nothing to do when they came over. They went to the ICU to find Yang Ping.
Can you be of any help?
The ICU is very busy now. Everyone is very active and actively participates in the diagnosis and treatment of firefighters. Director Gao and Director Fang cannot get involved and can only act according to the situation.
Sure enough, just as Yang Ping predicted, Fang Liu and Lao Xiao were weaned off the ventilators three days later, and other firefighters were also weaned off the ventilators one after another.
Because nursing work such as sputum suctioning was done well, and some antibiotics were used preventively, they did not develop lung infections. The subsequently damaged lung parenchyma was slowly repaired, and the exudation in the lungs was slowly absorbed by itself, and they were no longer able to breathe.
After being discharged from the machine, their breathing was very smooth and their vital signs were stable, so they were all transferred to the general ward.
Fang Liu and Lao Xiao were transferred to the ward of the Institute of Surgery. The head nurse led the nurses and held a small celebration for them. The happiest people were Lan Xueping and Wang Xiaojing, who finally saw their lovers alive and kicking.
Fang Liu was very surprised to see that Lankoping could stand and walk independently now, which showed that the effect of this operation was very good.
According to Zhang Lin's inquiries, none of the firefighters sent to other hospitals had major problems and they are all currently recovering.
Fang Liu and Lao Xiao, Zhang Lin and Xiao Wu serve as bedside doctors, each in charge of the other. Zhang Lin is in charge of Fang Liu, and Xiao Wu is in charge of Lao Xiao. Zhang Lin and Xiao Wu are not only the golden hooks of the surgical institute, but also surgical researchers.
Senior resident doctor at the institute.
Although they have been promoted to attending doctors, some key patients are still directly managed by them.
Fang Liu became Zhang Lin's patient. How could Zhang Lin let go of this opportunity? Every time he made rounds, he conducted face-to-face interviews with Fang Liu and learned clearly about the thrilling process of fighting the fire at that time. This was a real incident.
First-hand information, first-perspective information obtained directly from Fang Liu's mouth.
Because Fang Liu had been living in the ICU before, even reporters from all walks of life had not interviewed him face-to-face. Zhang Lin could be said to be the first person to interview Fang Liu face-to-face. After getting the information, he organized it and began to broadcast exclusively in the hospital.
, now colleagues in the hospital don’t hate him, but like to get information from him, knowing that he really has an intelligence source.
At first, news from all directions said that many firefighters had sacrificed a lot. Only Zhang Lin's inside information said that all firefighters evacuated safely and no one died. Later facts proved that Zhang Lin's inside information was very accurate and inspiring.
No, Zhang Lin went to a pediatric consultation and was surrounded by pediatric doctors and nurses. He had no choice but to sit down and start using his expertise.
"It was thrilling at that time, life and death were on the line!"
"After Fang Liu's squadron rescued the people trapped inside, they saw that the fire was getting bigger and bigger, and it had a tendency to spread out of control. What was around them were factories, companies, and people. Our firefighters
Without fear, they put their own lives and deaths at risk and decided to enter the center of the fire to put out the fire so that they could control the fire as quickly as possible. Before entering the center of the fire, team leader Lei Bin asked the factory director, what is stored in your warehouse? Are there any explosives? This factory
He hesitated for a moment, then said loudly, no!"
''Let me ask you again, are there any explosives? Captain Lei Bin saw that the factory director lacked confidence, so he asked loudly again, because he had to find out what was inside before he dared to let the firefighters in."
"They are all daily processing materials, and there are absolutely no explosives! This time the factory director patted his chest and said."
"In this way, Captain Lei Bin led the firefighters to open a path with water, step by step deep into the center of the fire source, that is, the warehouse where the fire broke out, and put out the fire at the center of the fire source in order to control the fire. At this time, the veteran team member Fang Liu discovered the origin of the flames.
The color is wrong, he is an experienced veteran, and he is extremely smart. Fang Liu shuddered and immediately called the captain, captain! I'm sure there are explosives in the warehouse, and there will be an explosion soon!"
"When the captain heard the news, he was terrified. At this time, there were more than a hundred firefighters inside and outside the fire scene. More than a hundred firefighters. The oldest one was about to retire, and the youngest one was only eighteen years old. One hundred
There are so many people inside!"
"Captain Lei Bin received the news and immediately continued to report while commanding each squadron to evacuate urgently!"
"Everyone! Retreat! Retreat! Unconditional emergency retreat! An explosion is about to happen. Evacuate as far away as possible!"
"Hurry up!"
"At this time, all the people trapped inside have been safely evacuated. Our firefighters began to retreat as quickly as possible. Excellent discipline ensures that the order is faithfully executed by everyone. Retreat! Retreat! Retreat!"
"Captains Lei Bin and Fang Liu are very experienced. They immediately planned the nearest route and evacuated quickly from the center of the fire source. At this time, a big explosion was already brewing, and you could even hear the roaring and terrifying sound.
"
"They were the deepest squadron, so they took the longest to evacuate. They evacuated northwest, all the way to the outside of the building, and then continued to retreat."
This chapter is not over yet, please click on the next page to continue reading! "While still in the process of evacuation, boom! A big explosion happened."
"The earth shook!"
"Fortunately, all our firefighters had evacuated safely at this time, but the air wave generated by the explosion overturned them. Many of them fainted. Our people's soldiers arrived and rescued them."
Zhang Lin spoke vividly, as if he was at the scene at that time, and even assisted with some body movements while speaking.
Even the director of pediatrics gathered around to listen to Zhang Lin's story about fighting the fire, and he listened attentively.
"and after?"
Some people are still not satisfied.
"Later, Fang Liu and Lao Xiao were sent to the emergency department of our hospital. At that time, our department was also the main force involved in the rescue. I was the first to rush forward ---"
Zhang Lin was ready to continue talking.
"Why don't you go back to work?"
A female doctor said to Zhang Lin. Zhang Lin turned around and saw that this was his wife. He immediately stood up and left.
"Don't go, we haven't finished talking yet, there is still Fang Liu's heart-wrenching love story---"
"Next time, next time---"
Zhang Lin hurried back dejectedly.
Fang Liu and Lao Xiaoping had good physical constitutions and recovered quickly. The blast injuries to their lungs healed quickly, while the injuries to other organs were very minor, so they recovered faster.
In the ward, Fang Liu had already begun to plan her travel route again with a map. The improvement in her condition after the surgery also gave Lan Xueping a lot of hope for life. Especially after experiencing the difference between life and death with Fang Liu, she cherished the present even more.
The happy life decided that no matter how her condition develops in the future, she must live well and live a wonderful life.
---
Fang Liu and Lao Xiao recovered well, and Yang Ping no longer had to worry about their conditions. He continued his experiments.
Yang Ping's new project, finding the cause of tumor cell death, has been moving forward.
The results of the analysis of electron microscopy pictures of dead tumor cells have come out. The reason for the death of tumor cells is that for some unknown reason, the apoptosis process is initiated, causing a chain reaction, causing tumor cells to die one after another like a plague. Moreover, this "plague" has a negative impact on
For tumor cells, it is like a curse. None of the remaining tumor cells escape the curse and all die.
Cell apoptosis is an active and orderly way of cell suicide. It is controlled by genes. Unlike cell necrosis, it is not passive, but active, and often involves the activation, expression and regulation of genes. It is a
It is a basic biological phenomenon that plays a very important role in removing unnecessary or abnormal cells in multicellular organisms. It has a very positive effect on organisms.
For example, if a mutated cell, such as a tumor cell, appears in the human body, the body's immune surveillance mechanism discovers that there is a problem with the cell and immediately initiates the apoptosis program. Through a series of gene regulation, the cell eventually commits suicide and dies to avoid further division and growth.
Quantity may cause harm to health.
The total destruction of the tumor cell bank was originally an accident, but Yang Ping keenly realized that this accident might contain some surprising inside story, so he separated it and set up a separate subject to study it.
The structure of dead cells was photographed from the organelle level through electron microscopy, and a large number of photos were analyzed to trace the cause of death. From the results of the analysis of the data, it can now be determined that the cause of cell death is the activation of the apoptosis program.
The death process of every cell is completely consistent with the process of apoptosis.
The reason why cancer cells become cancerous is that they escape from the body's immune surveillance and ignore the death command issued by the body. That is, once the body's surveillance system detects cancerous cells, it will order the cancer cells to initiate the apoptosis process, which is to execute the death of the cancer cells.
program, but under certain conditions, cancer cells ignore the body's orders, forcibly block the death program issued by the body, and still go their own way and continue to divide and grow, thus forming cancer.
Although we now know that the way cells die is apoptosis, we don't know at which point the escape mechanism of cancer cells fails and external factors forcibly start the death process, causing these cancer cells to execute death orders one after another and commit suicide.
The manner of death was found, but the murderer has not yet been found.
Who is so powerful that he can successfully suppress the escape mechanism of cancer cells, lock them tightly, and then force them to commit collective suicide?
Yang Ping thought about this problem in the laboratory of the system space, and seized this clue to work backwards. If he could find the reason for initiating cell apoptosis, it might open up a new way for tumor treatment.
The cause of apoptosis may be a certain substance, or it may be non-material energy, information or other forms of existence.
Next, Yang Ping needs to analyze the electron microscope photos again. The content and goals of this analysis are different. Last time, he analyzed photos of different states of dead cells to find out the way and reason of death.
This time, we hope to find out what happened to the cells before they died, what new factors they were exposed to, or what mutations occurred in their genes, or they were affected by some kind of signal.
This kind of analysis was more complicated than the previous state analysis. Yang Ping sorted out the clues, and then decided to use the supercomputer function of the system panel again to analyze the changes that occurred inside and outside the cell before death, during death, and after death, especially the key points of the analysis.
In emerging substances, signals or mutated genes.
Yang Ping hypothesized the existence of the K factor, and he started the second step of the experiment, looking for the K factor and the initiating factor that initiates tumor cell apoptosis.
After planning all the details of the experiment, Yang Ping handed over the experiment to the system panel and robotic arm for execution.
As for my main topic, the search for spatial guidance genes, except for the spatial guidance genes of muscles, I have not yet obtained the spatial guidance genes of other organs.
The analysis of genes is a very difficult thing. There are countless gene points. What is the specific function of each one cannot be analyzed in a short time. It requires repeated analysis work and a lot of analysis work. After the analysis results are obtained, we must also design
Many experiments were conducted to verify whether the analysis results were correct or not.
These basic scientific research tasks are definitely not easy, otherwise countless scientists and laboratories around the world would not have made key breakthroughs after decades of research.
Basic research work involves a lot of data processing and trial and error. You may persist in research for many years and finally find that the route is wrong, and you need to re-plan the scientific research route.
This is why some of the world's top laboratories and companies have established technical barriers that make it difficult for latecomers to overcome them.
For example, several of the world's major pharmaceutical giants have accumulated a large amount of trial and error data in their laboratory databases. Do not underestimate these trial and error data. These are their core and most valuable resources. These are what they make it impossible for latecomers to surpass.
the biggest technical barrier.
As a latecomer, something that has invested a lot of talents, funds and decades of research is likely to have been in other people's databases for a long time. This thing has long been tested by them and is the wrong route.
The most suffocating thing is that no matter how hard the pursuers try, the so-called latest topics are still repeating their trials and errors decades ago.
This is why the world's major pharmaceutical giants have never changed hands. They rely on these trial and error data to firmly occupy the top of the pyramid, leaving no hope for pursuers to surpass them.
Yangping's system space laboratory makes trial and error, the biggest cost of scientific research, very cheap.