Academician Zhou Shan looked at the six female donkeys in front of him with bright eyes, and the tears in his mouth were almost flowing.
As a well-known contemporary expert in animal molecular genetics and breeding.
Zhou Shan has an extraordinary love and enthusiasm for the local donkey, a precious species that is almost extinct.
After all, for a biologist.
The thing that worried him the most was not stubbing his little toe on the corner of the closet, but seeing a certain species become completely extinct but being unable to do anything about it.
After Zhou Shan was imprisoned.
The few native donkeys he bred were taken away for euthanasia, which once made the biology giant think that he had personally destroyed the native donkeys, a unique donkey species in China.
But with the appearance of Brother Donkey and Sister Donkey, and the arrival of these six native female donkeys...
without any exaggeration.
Zhou Shan felt redeemed.
After a while.
A woman who looked to be in her early thirties with a single ponytail came quickly to Zhou Shan and handed a stack of documents to Zhou Shan:
"Old...well, Director Zhou, this is our breeding report on six local female donkeys. Please take a look."
Zhou Shan took the report and thanked him:
"Thank you for your hard work, Xiao Zhou."
Xiao Zhou replied that you were welcome, smiled politely at Xu Yun and Zheng Zu, then turned and left the scene.
"Xiao Zhou was a student I once taught at Huanong. She was very capable. When I was dismissed, she had just entered the first year of graduate school."
Looking at the other person's retreating figure, Zhou Shan sighed with emotion:
"Because of my involvement, Xiao Zhou was later assigned to other research groups. His postgraduate career was very unsatisfactory. After graduation, he was assigned to a research institute in a remote area."
"But when I contacted her some time ago, she still chose to join my team, but now she can't call me teacher."
Xu Yun and Zheng Zu were silent when they heard this.
In addition to being an academician, Zhou Shan was also the director of the State Key Laboratory of Agricultural Biotechnology at Huanong University.
With all kinds of auras attached to him, those who can join his research group are basically future stars with strong talents and abilities.
It may be a bit exaggerated to say that they can reach such heights as academicians and Nobel Prizes, but before the age of forty...or even thirty-five, there is basically no pressure to be awarded a high professional title.
But later Zhou Shan was imprisoned.
The 20 or 30 people were basically swept into research groups with little prospects, and most of them were ostracized within the group.
Among the students Zhou Shan originally taught.
17 people chose to graduate directly after completing the third year of master's degree, four dropped out, and only three continued to study for doctoral studies.
Xu Yun even heard that someone could not find a suitable job after graduation because of his experience with Zhou Shan, so he could only work as an insurance telemarketer.
How deplorable it is...
"Forget it, let's not talk about this anymore."
Then very quickly.
Zhou Shan waved his hand, dispelling the boredom:
"It's all in the past, let's look at the present."
As he spoke, he shook the document twice, adjusted his glasses, and read it carefully.
"The average number of white blood cells is 7.7x10∧9/L, the low value is 6.5x10∧9/L, and the peak value is 9.3x10∧9/L..."
"The average red blood cell count is 0.37..."
"Mean platelet volume 11fl..."
"The average red blood cell hemoglobin content is 14.3Pg..."
"Basophils 1.3%..."
A few minutes later.
Zhou Shan closed the document again, pondered for a moment, and said to Xu Yun:
"Xiao Xu, it seems that the soy milk from HKUST Dongyuan will not be ground by stone in the short term."
Xu Yun blinked when he heard this and asked tentatively:
"Academician Zhou, what do you mean..."
Zhou Shan hummed, raised the report in his hand, and affirmed:
"Yes, according to the test report, the six local female donkeys are in good health and very suitable for giving birth."
"At the same time, because there have been no male donkeys mating for a long time, a lot of estrogen has accumulated in their bodies, so..."
"Next, we can ask Brother Donkey to stop grinding and transport it to the breeding center to spray it with soy milk."
Xu Yun suddenly nodded heavily:
"no problem."
As long as these six female donkeys can get pregnant successfully...
Counting the one that the donkey girl was pregnant with, there will be seven or more donkey calves born in the future.
This way.
There is no need to worry about the supply of donkey hair for the time being.
Then looking at the six native female donkeys grazing, Xu Yun suddenly thought of something and said to Zhou Shan:
"By the way, Academician Zhou, I have a question - is there any way to correct or optimize the shortcomings of inbreeding in donkeys?"
The inbreeding Xu Yun refers to does not refer to the hybridization of horses and donkeys to give birth to mules, but the academic definition:
Refers to the mating behavior of two animals that share a common ancestor within three generations.
Most wild animals in nature avoid inbreeding, so inbreeding in animals today mostly occurs in artificially intervened environments.
in academic research.
This is the main method used by humans to obtain highly consistent characteristics of a certain animal.
simply put.......
It is the selective breeding of purebred animals by humans.
The most representative one is the breeding of pigeons.
For example, in the breeding of racing pigeons, people will select two pigeons that are very good at flying and have a strong memory of routes for breeding.
Among the offspring they reproduce, the two best offspring are selected for inbreeding.
In this way, the probability of producing high-quality racing pigeons will be greatly increased, and the offspring of inbreeding are also called purebred pigeons.
Except for pigeons.
The breeding method of inbreeding has also been applied to other domestic animals, such as rabbits, horses, cats, dogs, etc.
There is also the concept of backcrossing, which you can understand literally.
But on the other hand.
Although inbreeding of animals can produce animals with better certain characteristics, their genes will have great defects.
This chapter is not over, please click on the next page to continue reading! Take the donkey as an example.
Donkeys produced by inbreeding are mostly thin and small, and generally suffer from congenital organ failure, making them extremely susceptible to death.
Although inbreeding through artificial intervention, there is an opportunity to select native donkey individuals with strong hair.
But from a life perspective, this is actually not friendly.
Xu Yun is not the kind of person who has a particularly holy mother's heart, but he is not a pure businessman either.
At least it would be unreasonable for him to breed a bunch of local donkeys that died within a year or two just for their hair.
At present, he only has one donkey brother and seven local female donkeys. Regardless of the gender of the offspring, inbreeding is basically an inevitable result.
So if there is a chance, he still hopes to find a suitable balance point - at least to be worthy of Brother Donkey who came back from the Northern Song Dynasty copy with him, right?
At any rate, it can be regarded as sharing weal and woe...
Facing Xu Yun's question, Zhou Shan's face quickly showed a smile:
"Xiao Xu, you asked a very good question."
"Currently our native donkey sample only has one male donkey, so it is foreseeable that inbreeding is a high probability event - unless another native male donkey is found."
"But now even Chairman Zheng's connections can only find these six female donkeys, so the possibility of local male donkeys existing is not very high."
"So I think that in the next research, we can put our energy into how to neutralize the disadvantages of inbreeding of local donkeys, that is, functional gene recombination."
"Functional gene recombination..."
Xu Yun touched his chin and humbly asked for advice:
"Academician Zhou, I don't know much about this direction. Can you tell me about the success rate of functional gene recombination in animals?"
Zhou Shan shook his head gently, his expression not serious, but not very relaxed either:
"To be honest, the success rate is not very high."
"Currently, the functional gene recombination technology for animal inbreeding is relatively limited. The most commonly used technology is to do some targeted processing on the Cas9 segment, but organ failure will still occur."
"This can actually be seen from the news - if the technology matures, many animals such as ligers will have a new future, and related news will definitely be very popular."
Zhou Shan paused as he spoke, then continued before Xu Yun spoke:
"But the good news is that there have been some signs of breakthroughs in this area not long ago - although they are not obvious, they are indeed very promising."
"There is an article in Nature called "Inherent mosaicism and extensive mutation of human placentas" that states that many genetic abnormalities in the human body will be 'absorbed' by the placenta, leaving the normal ones to move on."
"Donkeys also have a placenta, so from this perspective, I think there may be a chance to make some breakthroughs."
"Anyway, there is still about a year until the calf is born, and it will take more than half a year for the calf to reach sexual maturity. We still have plenty of time."
Xu Yun nodded in agreement.
As Zhou Shan said.
Compared with other situations, the time limit for functional gene recombination is not that tight.
"correct."
Speaking of genetic recombination, Zhou Shan slapped his forehead again and remembered something:
"Xiao Xu, I almost forgot one thing - the hair-increasing agent we developed for local donkeys is almost ready, and it can be used for experiments with these six female donkeys."
"Hair enhancer?"
Xu Yun was stunned for a few seconds when he heard this, and then his eyes widened:
"Academician Zhou, are you telling the truth?"
Zhou Shan nodded, made a few gestures to the female donkeys, and explained:
"Well, through analysis of native donkey hair, we found that its hair follicles are very sensitive to oleanolic acid extracted from swert."
"On average, 1.0mg/ml oleanolic acid can accelerate hair growth by 17.6% under simulated conditions."
“In addition, according to our research, DHT is also highly effective in damaging donkey hair follicles.”
"So we tried RU58841 as an AR binding agent to prevent DHT from invading hair follicle cells - the subjects of this part of the experiment were mainly hybrid donkeys and adult donkeys, but the results were equally gratifying."
"So after the donkey brother sends it here, I plan to let it try these two hair-enhancing agents first. If it is effective, it will be popularized on all local donkeys."
"Very good!"
When Xu Yun heard this, he clasped his palms together, and a trace of joy appeared on his face:
"If the hair-increasing agent is effective, and with the arrival of the six newly arrived local donkeys, many of our projects can take greater steps."
"Academician Zhou, I'm afraid you don't know that many people outside are waiting for our toothpaste to be launched."
Hear this.
Zheng Zu on the side also nodded in sympathy.
Not long ago.
With the reversal of public opinion and word-of-mouth, not only the sales of ‘One Mantis Killer’ products have increased, but also
The 100 tubes of Qingzhao brand Yi'anji toothpaste that Xu Yun and others tried to sell were all sold out.
Now the first batch of users have generated feedback. Although the total number of comments is not large, the content of the reviews has almost praised Qingzhao brand toothpaste to the sky.
After all, the effect of this thing is almost immediate...
At the same time, compared with the fifth generation imidacloprid, the toothpaste market is not only five or ten times larger?
However, due to the limitation of donkey hair, the speed of toothpaste production is basically the same as squeezing toothpaste.
So if there is an unlimited supply of donkey hair.
This means that Yi'an bacteria can be expanded in large quantities, and the picture will not be too beautiful...
Xu Yun then continued to chat with Zheng Zu and Zhou Shan, teased the six-headed donkey girl some more, and then left the breeding center feeling refreshed with his belt tied.
.........
After leaving the breeding center.
Xu Yun met Tian Liangwei in the parking lot, and the two returned to the HKUST campus together.
In addition to welcoming Lu Xiao today, Xu Yun has one more thing to do.
This chapter is not over, please click on the next page to continue reading! That is...
Research on long-term storage of isolated point particles has reached the most critical node.
As the project leader and technical ‘main attacker’, Xu Yun of course had to be present in person.
When he rushed to the laboratory.
Including Lu Chaoyang, all members of the project team had already arrived at the scene first.
Well, Lu Chaoyang's team is also here.
Although Lu Chaoyang and Xu Yun had already divided into two research groups after completing the ground state treatment of isolated point particles on the first day.
But at such a critical juncture and when manpower is extremely scarce, everyone will come over to help more or less voluntarily.
Of course.
The prerequisite is that the two research groups must have a good relationship.
In reality, there are some project teams who are at odds with each other. If they rashly ask for help from the other party, they may "accidentally" make mistakes in certain links.
"Hello Dr. Tang..."
"Good morning, Sister Zhang."
"Have you eaten, Xuemei Ye?"
Xu Yun then greeted everyone and quickly came to the operating table.
Mentioned earlier.
When Xu Yun and others conducted the ground state experiment, the beam tube channel they used was a circular pipe buried underground with a circumference of more than 400 meters.
But in reality, the gravity gradiometer has to go to the sky.
So if they want to use isolated point particles in a gravity gradiometer, Xu Yun and the others must complete another thing:
Store the isolated point particles that become entities for a long time.
However, after being processed into the ground state, the isolated point particle only has an entity for only fifteen seconds.
The steady-state duration required in the application phase of the gravity gradiometer is at least several hours, so a breakthrough must be made in this aspect.
Now after more than a month of research, Xu Yun finally thought of a new plan.
After Xu Yun takes his place.
Tang Fei, who had been in charge of equipment management, adjusted his glasses and said:
"Dr. Xu, we have adjusted the equipment according to your requirements and can start testing at any time."
Xu Yun nodded to him:
"Very well, thank you all for your hard work."
After speaking, he whispered a few words to Lu Chaoyang, coughed slightly, and said to the audience:
"Okay, fellow juniors and seniors, please give us a final report on the status of the business you are responsible for!"
More than ten seconds later.
Responses came from various locations in the laboratory:
"The medium resistance power supply is normal!"
"The time-dependent evolving wave function algorithm is normal!"
"The AMO value of the second-generation light source is normal!"
"Strong magnetic fields on both sides are normal!"
"The relative accuracy of the MATBG device is normal, with a minimum value of 0.00003 degrees! The spatial resolution is four Mohr cycles..."
"I've ordered takeout. Let's eat boiled fish today!"
Seeing this, Xu Yun took a deep breath, and a trace of determination flashed in his eyes:
"In that case...the test will begin in five minutes!"
This nervous emotion has nothing to do with mentality, but because...
This is a ‘measurement’ of his own abilities:
He did not use any thinking card plug-ins for this experiment, and only relied on his existing abilities to customize a specific plan throughout the process.
Before using Wheat Thinking Cards.
The upper limit of his ability is probably that of a professor of ordinary majors in 985 universities...that is, the senior level. Popular majors may be above the deputy senior level and below the senior level.
But after using Wheat Thinking Card...
Possessed by a master who ranks among the top in the history of human science, even if it only lasts for an hour, Xu Yun's abilities have been greatly improved.
Not to mention that in the process of deducing Mersenne prime numbers, a large number of citations and exquisite problem-solving skills were used, which broadened the horizons and was not just as simple as "gaining knowledge".
Therefore, Xu Yun was eager to know what level his abilities had reached.
Therefore, for this experimental plan, he did not seek help from anyone or plug-ins, and completed the entire process independently.
The results of this experiment will not affect the selection of professional titles, but they can be fed back into the grade of the published journal.
And his entry point is...
Let the lone point particles without any electrical properties be converted into metastable electronic states for storage.
As for the negatively charged particle that 'denatures' the lone point particle, it is...
π meson.
Mentioned before.
After the solitary point particle has an entity, some of its properties become somewhat similar to atoms.
For example, having a flat extranuclear orbit.
After the project team detected the Fermi energy, it was found that the twist angle θ of this extranuclear orbit is very large, somewhat similar to the ecliptic inclination of Pluto.
In other words...
This is a track that can be "pried".
so what.
Xu Yun plans to let the π? meson enter the outer orbit of the electron core. Since the π? meson has a spin of 0, the solitary point particle will have a super-fine interaction.
You read that right, interaction occurs.
So who is the "mutual" object?
That's right.
Students with good memories should remember it.
When the 4685Λ hyperon was handed over to the solitary point particle, it was a pi meson... (hehehe, I didn't expect that)
This interaction will give the isolated point particle a superfluid-like behavior, and then irradiate it with a high-resonance near-infrared light, it will have...
Conditions for activating the cost trap.
Aboutfei trap is a term that was only defined in 2019. It is so unpopular that you may not even be able to find what it is.
But it doesn't matter if you can't find it, because even if you find it, you won't understand it...ahem...
all in all.
This is an advanced version of the magneto-optical trap principle similar to the Penning trap. If successful, it may extend the life of particles with nanosecond lifespans by more than 1,000 times.
The current lifespan of a lone point particle is fifteen seconds. If the lifespan is extended a thousand times, it will be fifteen thousand seconds.
That’s a little more than four hours.
Although for a gravity gradiometer, this time may still be somewhat insufficient.
But what was discussed at that stage already belonged to the category of battery life, and it was so simple than the current step of leaving the laboratory.
five minutes later.
After all debugging is completed, the experiment officially begins.
Xu Yun and the others are still using the same set of light sources today, and the first half of the process has basically not changed.
Still emitting mixed beam...
Then the collimator determines the coupling parameters through photons that do not participate in the reaction, and a ceramic plate with water-added borax falls from above the channel....
4685Λhyperon deceleration....
Then it hit another P-type semiconductor, and the baryon number lost conservation...
In just 10-^15 seconds.
Tens of thousands of pions appear around the P-type semiconductor.
The isolated particles are attracted by them and are 'teleported' back instantly.
After combining with mesons, it briefly gained entity.
The lifespan of this entity state is...
15 seconds.
According to normal conditions.
At this time, the temperature should be cooled down, and then the magneto-optical trap should be used to capture the solitary point particles.
But today, Xu Yun and others did not follow this step.
Watch the gradually smaller numbers on the display.
Zhang Han, who was responsible for operating the laser instrument, immediately pressed another button.
Swish——
A soft x-ray of 4.96x10^16 Hz is emitted. Through the energy conversion announcement, the corresponding energy magnitude can be calculated...
202 electron volts.
at the same time.
A stable quadrupole magnetic field with an inclination angle of 14.563 degrees appears around the solitary point particle.
In conjunction with soft x-rays, an anomalous Nernst effect appears.
Two seconds later.
Another research team member pressed a yellow button.
0.001 seconds passed.
A large number of negative hydrogen ions composed of a proton and two electrons are ejected, and the weak equivalence principle is expanded.
finally.
After 5.77 seconds.
A small crack appeared in the already tilted extranuclear orbit of a certain lone point particle...
call out--
A π-meson is like a Wu-tiao possessed, sneaking in every opportunity and quickly darting into the extranuclear orbit of the solitary point particle.
at the same time.
The computer background, which detected the change in the π-meson cyclotron frequency ratio, once again controlled the laser port to emit a beam of light, the unit was...
183760 GHz.
After 35 nanoseconds.
A change occurred:
(n, l)=(17, 16)→(17, 15)
Then under the ‘rubbing’ of those negative hydrogen ions.
A large number of isolated particles gather together to form a microscopic field...
Dough.
And here we are.
What happens next is very simple.
Children who have studied high school physics should have heard the teacher say the same thing:
Uncharged particles will not deflect in a magnetic field.
When I meet some teachers who are relatively indifferent, they will upgrade this sentence to "uncharged particles will not be affected by magnetic fields."
But in the field of quantum chromodynamics, this knowledge is different.
Almost all particles can be affected by an external magnetic field, even if they are uncharged - the effect here is not deflection, but other circumstances.
This involves the concepts of an electromagnetic coupling mode and multipole moment expansion.
It is known according to quantum mechanics.
Particles are dispersed in space and have a certain charge distribution, so particles can have non-zero multipole moments.
Generally speaking.
A particle with spin J can have 2J 1 electromagnetic multipole moment.
A particle is an electron, and the spin of the electron is 1/2.
Therefore it has an electric zero pole moment (charge) and a magnetic dipole moment (magnetic moment).
The most common multipole moments of a microscopic particle are charge, magnetic moment and electric quadrupole moment.
For example, if you put a neutron in a magnetic field, its spin will also couple with the magnetic field.
This belongs to the category of electromagnetic interaction - by the way, electromagnetic interaction not only involves magnetic fields, elastic forces, but also the forces between proteins are all electromagnetic interactions.
At present, the only particles that are definitely not capable of electromagnetic interaction are neutrinos.
Other than that.
Even photons can have this effect - if you are not afraid of dizziness, you can check out what virtual photons are.
all in all.
All particles will be affected by electromagnetic interaction, and the same is naturally true for the specially processed solitary point particle ‘dough’.
When the life span of the isolated point particle is only 4 seconds.
A prepared trap fell instantly, tightly binding the 'dough' together.
See this situation.
Everyone on the operating table couldn't help but slow down their breathing at the same time.
If the ‘dough’ is still there after four seconds.
This means that their experiment was not completely successful, but at least it achieved a breakthrough.
But if the 'dough' disappears, that means...
that's all.
Under everyone's gaze, time slowly began to pass.
4 seconds.....
3 seconds.....
2 seconds.....
1 second.....
When the time comes to the fifth second, ‘dough’...
Still hasn't disappeared.
See this situation.
Li Ruo'an, who was in charge of radio frequency field debugging, suddenly thought of something and started typing on the keyboard quickly.
More than ten seconds later.
He raised his head suddenly and looked at Xu Yun with bright eyes:
"Dr. Xu, the decay of ground state solitary point particles has slowed down!"
"According to the observation of the perturbation wave function, the decay period of these solitary point particles in the JF trap is..."
"About 4.6 hours!"
Hear this.
The scene suddenly fell silent.
After a while.
A burst of cheers suddenly resounded throughout the laboratory:
"great!!!!"
"Ula!!"
Xu Yun on the operating table also waved his fist vigorously, with a hint of excitement in his eyes.
This is a technological breakthrough achieved through his own efforts, which is extraordinary in its significance.
In addition, in terms of results.
This is an achievement several times more difficult than ground state processing.
If ground state processing can only be shortlisted for papers in the first area, then this "life extension" technological breakthrough is undoubtedly...
CNS-level results—still the kind of main journal.
Currently, the CNS main journal publishes about 4,000 articles a year, and Chinese authors publish about 200 articles a year. (You can search it on the new web of science platform.)
A 25-year-old young man published CNS as a first author, which is obviously an achievement worth being proud of.
Of course.
Again.
There are many talented people in the world. Although the case of CNS at the age of 25 is not common, it is not an isolated case.
For example, Cao Yuan and Cao Shen, who also graduated from the Youth Class of HKUST.
At the age of 22, he published two papers in Nature as the first author and co-corresponding author.
Up to now.
Cao Yuan, 28 years old this year, has published 8 articles in Nature and 1 article in Science, and even published 4 articles in a year...
As for the global scale, it is even more outrageous.
For example, the youngest publisher of "cell" is named Danielle Bassett, who just celebrated her 17th birthday three days before releasing "cell"...
The youngest author in the world of "Nature" is called Konstantin Batygin, a member of the team of Pluto killer Mike Brown.
When the first game was released, he was only 18 years old.
Compared with these geniuses, Xu Yun still has a long, long way to go.
Think of this.
He couldn't help but take a deep breath and force himself to calm down.
Then he took out his cell phone and made a call.
After a while.
Academician Pan's voice came from the other side:
"Hello, Xiao Xu?"
Do not know why.
When hearing Academician Pan's voice, Xu Yun always felt that something was wrong with his tone.
But this was just a hunch that he had no basis for, so he quickly dismissed this thought and got down to business:
"...Teacher, this is almost the situation. Now it seems that the lone point particles can be released from the laboratory."
Academician Pan, who was on the other end of the phone, listened quietly to Xu Yun's introduction, was silent for a moment, and then suddenly said:
"Xiao Xu, you said that you applied an approximate cost trap to the ground state lone point particles, right? In that case..."
"Have you and Xiao Lu done any research on the electromagnetic interaction force of isolated point particles that have not formed a ground state?"
".....ah?"
Xu Yun was stunned when he heard this and said subconsciously:
"I haven't done it before. Isn't this the project that you and Academician Zhao are responsible for, teacher?"
There was silence again from the other side.
Just when Xu Yun thought there was something wrong with the signal, Academician Pan's voice sounded faintly again, even with a hint of...
vibrato.
"You and Xiao Lu should seize the time to make an observation now. Then you will understand what is going on."
Then Academician Pan paused and added:
"Be ready to take some quick-acting Jiuxin Pills when you look at the results. Something big has happened."