After Chen Jinhe heard Chen Nan's words, he was stunned for a moment.
However, he didn't quite understand what Chen Nan meant.
"standard?"
"What are the quality standards for traditional Chinese medicine pieces?"
"Or...what?"
After Chen Jinhe thought for a long time, he still couldn't think of a reason for setting standards. Setting standards for traditional Chinese medicine pieces is definitely not an easy task, and there are many things involved.
It is definitely not a task that Annan Pharmaceuticals alone can accomplish.
Let alone them, even Xinke Pharmaceutical Company does not have such ability, strength, and rights!
The production of a standard, especially a Chinese medicine standard, involves too many things.
If you create a useless standard and others don't recognize it, what's the point?
Of course, Chen Jinhe, who has been immersed in this art for many years, naturally understands the truth.
What a first-class enterprise does is standard!
"Chen Nan, have you thought about this question? The preparation of Chinese medicine standards is by no means an easy task."
At this time, Chen An smiled slightly: "Dad, you may have misunderstood what Chen Nan meant!"
"The standards for traditional Chinese medicine are indeed beyond what a small company like us can achieve."
"But, have you thought about a question?"
"I am doing chemical research myself, especially the research on the specific active substances of these traditional Chinese medicines."
"This is my professional advantage."
"Secondly, you know what?
Currently, less than 70 types of traditional Chinese medicine have international standards.
The demand for herbal medicines in the United States is also increasing year by year!
The development of new drugs has always been a big problem. Each new drug requires an investment of more than one billion US dollars in scientific research funding.
Therefore, they began to change their perspective and conduct research on active substances of traditional Chinese medicine.
As for the University of California, the main task of our research institute in recent years has been the exploration of active substances in traditional Chinese medicine.
China and the United States have signed a memorandum of cooperation on pharmacopoeia work since 2008. Currently, there are 13 traditional Chinese medicines and 46 standards are included in the US Pharmacopoeia, including salvia miltiorrhiza, Panax notoginseng, Ganoderma lucidum, Schisandra chinensis, honeysuckle, Polygonum multiflorum, cassia twig, coix seed, red ginseng, etc.
33 standards for 9 traditional Chinese medicines were completed by Chinese scientists.
Twenty-four Chinese medicine standards such as Angelica sinensis and Ligusticum chuanxiong have been submitted to the United States Pharmacopeia. Salvia miltiorrhiza, Panax notoginseng, Ganoderma lucidum, Andrographis paniculata, and Centella asiatica are both listed as food supplements (DSC) and herbal medicines (HMC).
The European Pharmacopoeia has also included 66 Chinese medicine standards such as Salvia miltiorrhiza and Panax notoginseng, 4 of which were formulated by Chinese experts, and more than 20 Chinese medicine standards have been submitted to the European Pharmacopoeia and are under review."
"Currently, the person in charge of formulating this standard in China is Professor Guo De'an."
"He was the first Chinese team to formulate the standards for Chinese medicines in the United States Pharmacopoeia and the first Chinese team to formulate the standards for Chinese medicines in the European Pharmacopoeia. He himself is not only the vice chairman of the Herbal Medicine Expert Committee of the United States Pharmacopoeia, but also a member of the European Pharmacopoeia Committee."
“At the University of California, research on active substances in traditional Chinese medicine has always been outsourced.”
“The University of California receives as much as US$190 million in funding for research on active substances in traditional Chinese medicine every year!”
"This is definitely an exaggerated number!"
"My brother's intention is not to simply return to the old business and continue to simply make Chinese patent medicines."
"But we need to get some extracts of traditional Chinese medicine active substances, which are the new standards."
"For example, I won the Chemistry Prize last year because I discovered a new active substance in Panax notoginseng."
"Subsequently, the United States Pharmacopeia included this new substance into the standards of traditional Chinese medicine."
"I believe that since the United States is doing it, the country is also doing it!"
Chen Nan glanced at his brother in surprise, feeling shocked inside!
He didn't expect that after just saying a little, his brother understood what he wanted to do.
At this time, Chen An continued: "Chen Nan, the direction you are thinking of is very good!"
"but……"
"I want to remind you that each traditional Chinese medicine has seven or eight standards, and it is definitely not easy to study and discover the substances in it."
"Our team includes a Nobel Prize winner, seven or eight international chemistry prizes, and American chemistry prizes. In addition, there are a lot of professors and Ph.D.s... all working on research."
"This road may not be feasible!"
"You should know that Mr. Tu Youyou's extraction and discovery of artemisinin was definitely not something that could be accomplished overnight."
Chen Nan smiled: "Brother, I think you may have thought a little wrong!"
"Chinese medicine is the wealth left to us by our ancestors!"
"It is true that the chemical and physical levels of the West are far from what we can currently match, but... our country's research on traditional Chinese medicine, which has been going on for thousands of years, is definitely not what the West can match."
"I just want to ask you something!"
"If we can solve a new substance, or obtain a standard for an important substance in traditional Chinese medicine, do you think we can make money?"
Chen An nodded: "It's undeniable! You can definitely make money."
"As far as I know, China's investment in this field is huge every year."
"A large number of team members, spending countless manpower and material resources, and countless resources are working on it."
"Moreover, Professor Guo De'an also cooperates with us in domestic research institutes. To put it bluntly, this is a kind of outsourcing."
"A type of technology outsourcing."
"Every year, the country spends countless amounts of money in this field. In fact... our country has always wanted to unify international standards and let the Chinese people decide on the standards of traditional Chinese medicine."
"Unfortunately, the difficulty is too high."
"If we can develop a guarantee for traditional Chinese medicine, and it is recognized by the Chinese Pharmacopoeia, the European Pharmacopoeia, and the United States Pharmacopoeia, and if this new substance has significant effects, it will bring tens of millions to 100 million in the United States.
The income ranges from US dollars, which will save the country nearly 300 million yuan."
After Chen Nan heard this number, he was stunned for a moment!
He didn't expect... there were so many?!
A new standard can actually make so much money directly.
The hapaside propionate he just obtained is undoubtedly one of the active substances of Eucommia ulmoides.
And it is an extremely remarkable substance.
The human body's two-way regulating substance is itself a very valuable thing.
The anti-fetal effect of Eucommia ulmoides is based on the two functions of uterine contraction and uterine relaxation based on human hormone levels. If it can be studied and utilized, it will definitely be a good thing for the modern research of Eucommia ulmoides.
If you think about it this way...it seems that 100 million US dollars is not much.
Because this will introduce a new drug for miscarriage, the price of miscarriage drugs will remain high.
Johnson & Johnson in the United States has a new drug priced at 2,000 yuan. This drug brings nearly 2 billion U.S. dollars in revenue to Johnson & Johnson every year.
Chen An continued: "However, there is a problem. Traditional Chinese medicine is a complex system with multiple components, and the single-index component quality control model of chemical drugs is not suitable for traditional Chinese medicine.
So which are the important ingredients and require series of studies is also a question.
Not every active substance in traditional Chinese medicine has research value.
In my opinion, the overall idea of constructing quality control standards for traditional Chinese medicines is to proceed from in-depth research to simple explanations of standards. First, the active ingredients of traditional Chinese medicines are elucidated through a research model combining chemistry and biology.
Secondly, the research is transformed to build overall quality control standards, and finally the established standards are applied to actual control of product quality."
"In addition, there is another problem. Obviously, although many domestic research institutes have appeared in recent years, most of them are not easy to do. The country's outsourcing funds are strictly controlled, and they will never be casual.
Just take it out."
"We can become a subsidiary institution and a listed research institute."
"I do know Professor Guo De'an. After I came back, I visited him once. He hoped that I could join his research institute."
"However, I refuse for the time being."
"Professor Guo appreciates and recognizes me very much. I think... maybe we can cooperate with them."
"If we have results, we can even...become an independent research institute."
At this moment, the family stared at Chen An, a little surprised!
Unexpectedly, he actually had such a friendship with Professor Guo De'an, the head of the international standard setting team.
Chen An saw the whole family staring at him with expectation and surprise, and felt a little embarrassed for a moment.
"Don't look at me like that."
"We have no qualifications, no foundation, and no results. People may not recognize us, and we can't get outsourcing funds."
Chen Nan smiled: "I happen to have a new active substance here. After checking the information, I didn't find any research records. I think... Brother, you can try it."
"Maybe we can get cooperation opportunities!"
Chen Nan was originally worried about how to demonstrate his standards reasonably.
After all, you can't just give standards to the country casually, right?
Whether they will vivisect themselves is a question!
But I actually have such an opportunity!
It seems...everything is going smoothly.
The "harpaside propionate" in Eucommia ulmoides can obviously help Annan Pharmaceutical overcome the first difficulty, and can also display these standards in a reasonable, legal and compliant manner.
As the old timers said.
"Traditional Chinese medicine is produced in China and is the wealth left by our ancestors. China must set standards!"
We can make standards, why should we send them to other countries to make them?
Why can’t we use the things we research ourselves?
After Chen An heard Chen Nan's words, he was stunned for a moment: "Are you sure?"
Chen Nan nodded and smiled: "Of course!"
"This is an extract of Eucommia ulmoides. I recently met a patient who was hospitalized due to miscarriage."
"As for Eucommia ulmoides, it has always been a miscarriage medicine, and its ultimate effect in preventing miscarriage is a two-way regulation."
"Ucommia ulmoides can cause uterine relaxation when used in large doses. This is a theory that has been studied so far."
"But in addition, there is a substance in Eucommia ulmoides. This substance is not yet known, but animal experiment results show that this substance can regulate the central nervous system in two directions according to human hormone levels. In the early stages of pregnancy,
It causes the uterus to relax, and in the third trimester of pregnancy, it can appropriately excite the uterus."
"I think this substance is of great research value."
"I think, brother, you can study it and give it a try."
After Chen Nan had previously obtained a drug with a two-way regulatory mechanism, hapaside propionate, he had actually studied whether Han Mingliang's punishment was reasonable.
but!
Soon, he rejected his idea.
Because the patient takes a large amount of Chinese patent medicines, even if there is hapaside propionate, the patient's large dose of Eucommia ulmoides will cause the patient's uterus to relax, causing cervical relaxation, leading to miscarriage.
Essentially, Han Mingliang must have committed a drug overdose.
However, "Xinke Naoxintong Capsules" produced by Xinke Pharmaceutical Company also have problems.
and!
This also shows that the processing of Eucommia ulmoides by Xinke Pieces Company is also unqualified.
Simple temperature control cannot guarantee the reasonable release of the active ingredients of Eucommia ulmoides.
Looking at the two children, Chen Jinhe and Chen Wenyin looked at each other and were filled with joy!
The child has grown up!
I can now stand alone.
This makes both of them happier than the company's resumption of operations.
Chen Nan hid the name and chemical formula of hapaside propionate, otherwise... there would really be no way to explain how he obtained it.
However, with my brother’s strength, it should be possible to research it, right?
After all, I have already reminded myself to this point.
"Dad, Mom, please celebrate the New Year in peace first!"
"You don't have to worry about the company's matters."
"After we solve this problem, the country will have a dedicated channel for tablet companies."
"By then, our medicinal material problem will be solved."
Chen Jinhe smiled helplessly and nodded: "Yes!"
"Honey, let's celebrate the Chinese New Year well."
"I'll go buy new year's goods tomorrow and do some logistical work for the two future scientists and doctors."
At this time, Chen Nan suddenly said:
"Dad, there is one more thing."
"Our hospital may soon obtain the qualification to produce and sell in-hospital preparations."
"At that time, a company will be invited to bid as a cooperative enterprise."
"I think you can try it."
"After all, our Annan Pharmaceutical has also made achievements in Shanxi Province, and we are satisfied with it in all aspects."
Chen Jinhe was stunned when he heard the news about Chen Nan.
this……
Is there really such a thing as a pie in the world?
The in-house preparation company of the Provincial Hospital of Traditional Chinese Medicine was originally called Rising Pharmaceuticals and was on the verge of bankruptcy, but what about now?
The business is booming, and following the success of the Provincial Traditional Chinese Medicine Hospital, the business is developing very well.
Although the profit is a little less, but... the sales channels are stable!
This does not affect the normal operation of the company.
Looking at Chen Nan, Chen Jinhe looked at his wife dumbfounded: "Wife!"
"Did you see that?"
"When I first returned to China, your son pointed at Yuancheng City and said to me, look, this is the country your son has built for you!"
"At that time I thought this little bastard was trying to make me happy."
"Now it seems... Haha, isn't this it?"
"Why!"
"I can't stand it anymore!"
Chen Wenyin looked at Chen Nan getting more and more energetic, and her inner pride was naturally unbearable. She looked at the two children with a smile, and her inner joy could not be calmed down for a long time.
…
…
the next day!
As soon as Chen Nan arrived at the hospital, he received a call from JC Traditional Chinese Medicine Hospital.
"President Chen, we have a special patient here. The situation is too serious!"
"Severe viral meningitis."
"Now the patient has no way to transfer to another hospital. The situation is a bit serious. Do you have time? Could you please come down and help me?"
After Chen Nan received the call, he was stunned for a moment.
The director of the JC City Traditional Chinese Medicine Hospital is He Yuanshen, who is a director of the Shanxi Traditional Chinese Medicine Physicians Association. The two have chatted for a long time.
Chen Nan quickly asked: "Dean He, what is the specific situation?"
He Yuanshen sighed:
"The patient is a medicine farmer. He used to be a good hand at processing traditional Chinese medicine. He is a famous old pharmacist in Jincheng!
But...he suddenly became sluggish and silent while working in the fields this fall. He seemed to wake up again about ten minutes later and went home to rest. Sometimes he was irritable, sometimes depressed, and gradually became unconscious.
He was hospitalized successively and diagnosed with "severe viral encephalitis". We gave him anti-viral, anti-infective, and lowering intracranial pressure, but the treatment was ineffective after more than 10 days.
He also suffered from paroxysmal opisthotonus and kept crying out. However, anti-epilepsy, correction of water and electrolyte balance and symptomatic treatment were not effective.
Now the situation has become more serious, and the disorder of consciousness has deepened. I went to the First Affiliated Hospital of Xiangya Medical College, but... the other party advised his family to give up treatment."
"I'll be back here..."
"After I came back, my family members still refused to give up, but there was nothing they could do at home, so they stayed in our hospital."
"The patient's condition is very troublesome now. We don't have the conditions for transport here, so we have to trouble you to come down."
"Don't worry, our hospital will pay for the consultation fees!"
Chen Nan heard the sound, thought for a moment, then raised his hand and looked at the time: "Okay, I will be there before noon today."
When He Yuanshen heard this, he nodded excitedly: "Thank you so much, President Chen!"
"thank you!"
Chen Nan hung up the phone, warned Zhao Jianyong, got up and drove there directly.
However, as soon as they got in the car, Chen Nan received another call.
Tao Gongshu said anxiously: "Xiao Chen, something's wrong!"
"Now we have received a lot of complaint letters here, all about you."
"And the National Health Commission also asked us to investigate you."
"They feel that the punishment you gave Han Mingliang was a bit unreasonable, and they also think you are suspected of using the acute respiratory syndrome specialist to canvass votes to influence the election."
"This is a fucking excuse!"
"There is clearly a problem on Han Mingliang's side."
"To put it bluntly, those people are deliberately looking for trouble."
"I just feel that your idea of making some people rich has been shattered and you have restricted Xinke Pharmaceutical Company's drug sales."
After Chen Nan heard the call, he immediately became silent.
After a moment, he suddenly smiled and said:
"right!"
"There is indeed a problem with Han Mingliang's medical dispute!"
Tao Gongshu was stunned: "Ah?!"
"Xiao Chen, don't talk nonsense!"
"What's going on?"
Chen Nan smiled: "There is no doubt that Han Mingliang has problems."
"There is no doubt that the use of large doses of drugs, beyond the scope of pharmacological standards, will cause miscarriage in patients."
"but!"
"In addition, I found through experiments that Xinke Xinnaotong capsules produced by Xinke Pharmaceutical Company also have big problems!"
"Their drugs carry the risk of miscarriage for patients in the third trimester of pregnancy, and they are clearly marked for use by pregnant patients. This is the problem!"
"There are problems with their drug instructions and drug certificates!"
"Dean Tao, I have submitted an application to the Food and Drug Administration, requesting that this drug be removed from the shelves and rectified."
"I guess the results will be out today."
Tao Gongshu was immediately dumbfounded.
This...what and what?
"Xiao Chen, if something happens, can you come over to my place and explain it in detail?"
Chen Nan smiled awkwardly: "Sorry, Dean Tao, I have to go to Jin Province now."
"I probably won't be able to go!"
"Let's talk about it when I get back."
Tao Gongshu was dumbfounded: "Don't be here at this...this critical moment!"
"I'm afraid that the Health Commission will talk to you."
Chen Nan chuckled: "I didn't do anything wrong, why should I cooperate with their investigation?"
"Since they want to check me, just wait!"
After saying that, Chen Nan hung up the phone directly.
Tao Gong was left stunned in place, speechless for a long time...
this……
…
ps: I wrote a little less today, mainly because it was a bit troublesome to look up too much information.
I checked the details of the current Chinese medicine standards at home and abroad. After checking, I had to sigh...it is controlled by others!
It is obviously our traditional Chinese medicine, but the West has the final say!
Why?
Because people think we don’t know enough about Chinese medicine.
Damn, this is so frustrating.
I wrote this plot because I hope that one day Chinese medicine will be available and the Chinese people will have the final say!
The active substances of traditional Chinese medicine can be used by us Chinese ourselves!