The gentle classmate Pan didn't want to say anything when he saw classmate Xie, but took the initiative to explore the way ahead: "I think the most important thing is the suitability."
If the glimmer in Cao Yong's eyes nodded to his junior brother's answer, it seems that many junior brothers are also talented.
In a nutshell, what Mr. Pan said refers to areas that are not suitable during organ transplantation. Doctors may be able to use clever methods to make them suitable, which is called suitable.
"Yingying, what do you think?" Pan Shihua asked classmate Xie for his opinion.
Senior Brother Cao and Student Wei looked over as if they wanted to hear what she had to say. Xie Wanying said: "Where is the limit of suitable technology, and where is the upper limit of organ transplant surgery."
This is a further academic interpretation of Pan’s words.
Classmate Wei and classmate Pan’s eyes seemed to be lit up with little stars. Cao Yong’s mouth couldn’t smile.
How to understand what Mr. Xie said?
Let me first talk about the liver transplant surgery that I have seen before. At that time, Xie Xie participated in the operation and gave suggestions. The difficulty for the doctors during the operation was attributed to the fact that the donor liver was too large and unsuitable. It had to be cut into small pieces. This was a problem of fit.
The donor-recipient ratio has always been a basic threshold in all organ transplant surgeries.
Liver transplant surgery has such technical difficulties, and heart transplant surgery also has such technical difficulties.
Is it possible to transplant a heart like a liver transplant, where the donor heart is cut into a smaller size to fit the transplant? Xie shared his knowledge with Reporter Li and said that for example, the ratio of a pediatric donor heart can be 2.5 times larger than the recipient's original heart.
Regarding this crux, anyone with some common anatomy knowledge will know that the heart cannot be like the liver. The liver and heart are completely different in form, function and structure in all aspects.
The overall structure of the heart is closely related to its function. The liver is not. The function of the liver mainly depends on liver tissue. This causes a donor liver to be cut into two for two recipients. How is it possible for the heart? The heart
The requirements for the donor-recipient ratio are really stricter than those for liver transplantation. Let me talk about another trivia point here. For liver transplantation, there is no need to worry about the donor being too small. On the contrary, for the heart, as Xie said, it is best for the pediatric donor heart ratio not to be smaller than that of the recipient.
The original heart's value of 0.9 indicates that the acceptance rate of small donor ratios is much lower for heart transplantation than for liver transplantation.
Why is this?
The main functional output of the heart is to recycle blood throughout the body. There is no need to worry if the donor is larger. This is because many patients who need heart transplants have heart disease themselves, which causes the myocardium to expand and the heart volume to become larger. The volume of the place where the heart is accommodated increases and the volume can be accepted.
A larger heart. Of course, it cannot be too big, as this will also cause postoperative secondary hypertension and other problems.
In contrast, the problem caused by a donor that is too small is difficult to solve: low cardiac output. Many heart disease patients die from this problem in the end stage. If the transplanted heart fails to solve this important problem, the result is likely to be a wasted transplant.
Already.
In terms of practical clinical application, it turns out that young children should choose older donor hearts as much as possible. Female patients should choose hearts from male patients. Male patients should be cautious and cautious when accepting a heart from a patient that is too small for their own weight.
These are precisely what Xie pointed out as the "suitable" technical limits determine the technical limits of organ transplantation, and they are all difficulties that need to be solved during the operation.
Just in terms of ratio, the threshold for heart transplantation is higher than that for liver transplantation. Heart transplantation must be more difficult than liver transplantation, otherwise it would be unfair to be called two major surgical specialties.