While eating, I chatted with Teacher Tan about scientific research.
Teacher Tan is an expert in laparoscopy, general surgery, and gastrointestinal surgical oncology. Teacher Tan’s traditional surgical procedures are as first-class as laparoscopic surgeries, and his extraoperative treatment plans for tumor patients are also top-notch.
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It would be ridiculous to imagine that the scope of academic research that Mr. Tan can do is limited to laparoscopy. For example, the fairy brother rarely performs heart transplants, but he will research auxiliary devices for end-stage cardiac treatment.
For surgeons, surgery is an advantage when engaging in scientific research, as it can conduct research on various surgeries. On the other hand, surgeons have an advantage in the field of basic subjects, which mainly refers to the pathological specimens obtained by surgeons.
Advantage.
It is too easy for surgeons to capture surgical pathological specimens of various patients' tumors during surgery. Unlike other departments, it is difficult to obtain the pathological specimens they want. The specimens obtained by medical endoscopic examination are limited in scope, which is far less than
Surgery. In this way, you will find that surgeons who are the masters of basic research can actually be as good as physicians and pathologists or even better.
Teacher Tan happens to be such a big shot.
Speaking specifically of the topic studied by Teacher Tan, we can talk about a large class of star anti-tumor drugs that have become famous since the 21st century: targeted drugs.
Targeted drugs are like arrows aimed at the "protrusions" of tumors. Compared with chemotherapy drugs, they are like spraying pesticides when attacking tumors. They are more precise and avoid harming healthy human tissues. They are warmly welcomed by doctors and patients. Targeted drugs
The advantage of targeted drugs is accuracy. The accuracy of targeted drugs is based on the target. Finding the target of targeted drugs has naturally become the top priority for scientific researchers.
The study of targets is essentially inseparable from the study of tumor pathogenesis.
The pathogenesis of tumors is complex, and there are many links and substances involved in tumor pathogenesis, all of which can be targets in theory. For example, the most common substance receptors, transporters, enzymes, ion channels, genes, etc., many of which have been in the
It is a basic topic of research. Here is a relatively new research topic that was discovered and proposed only in recent years, called microRNA.
MicroRNA, to understand it simply, can be said to be a substance like intestinal flora. Good microRNA can inhibit tumor tissue after being absorbed by humans. Bad microRNA can promote the growth of tumor tissue. Based on this principle, medical oncology
If we study the former, we can make it into a tumor suppressor. If we want to deal with the bad things in the back, it would be most suitable to make a targeted drug for "chut" attack.
Medical discovery is that it is better to suppress tumors than to kill them. How cutting-edge are microRNA-targeting drugs? According to the information that Xie Wanying, who came back from the future, knows, it is a new trend in targeted drugs in the future.
In any case, as mentioned before, to make targeted drugs, you must first find the target, and to make RNA-targeted drugs, you must find microRNAs. The key topic of Teacher Tan is the study of colon cancer microRNAs, and in a wide range of colon cancer specimens
A brand-new microRNA was discovered in the study, which can theoretically become the target of new targeted drugs for colon cancer. It is a key area at the forefront of oncology research around the world.
Teacher Tan's research project is so cutting-edge, and Xie Wanying must have said that she can't dictate what the teacher's research is.
