This is why Cao Dong's first impression when observing this pathological section was that of myocardial necrosis. It is true that a characteristic of myocardial fibrosis is the death of myocardial cells.
Dr. Cao Dong's main job is as a clinician, and his speech is relatively straightforward and straightforward.
If scientific researchers want to conduct in-depth academic discussions, they cannot simply talk about myocardial fibrosis in a general way, nor can they give the impression that it is a slice of myocardial necrosis. The accurate statement should be a pathological description, and then give a patient diagnosis to this slice.
Likewise, it cannot simply be said to be slices of myocardial necrosis.
The first point that needs to be made clear is that myocardial fibrosis is a pathological diagnosis term, not a disease name. It is actually divided into two types. One is reactive fibrosis, which occurs around blood vessels and is the response of the myocardium to myocardial load and inflammation.
of lesions.
Through this definition, we can know that this pathological lesion usually occurs in patients with myocardial load or inflammation, such as patients with hypertrophic cardiomyopathy, left ventricular hypertrophy, aortic stenosis, myocarditis, etc.
Recalling the cases we mentioned before, it can be roughly inferred that patients with valvular cardiomyopathy are expected to have this disease. The reason why it was not mentioned in detail before is because pathological anatomy cannot be performed in vivo to perform this examination.
, can only do a myocardial biopsy. Myocardial biopsy around blood vessels is not easy to do and the potential risks to the patient must be considered.
What we are talking about now is to talk about the significance of scientific research. Doing pathological analysis after death is like an afterthought, but a thorough study of the pathogenesis can bring good news to other patients. It can be said that every patient is sacrificing himself to benefit the future.
Patients and human medicine are the ones that best demonstrate the great justice of mankind and the true meaning of a community with a shared future.
Another type of myocardial fibrosis is the reaction to myocardial cell death mentioned above. Repair scar formation after myocardial fibrosis is called repairing fibrosis. It often occurs not around blood vessels, but in the myocardial interstitium, corresponding to
A common patient type is myocardial infarction and myocarditis patients.
When it comes to specific clinical cases, in cases of ventricular remodeling, the two types are often mixed together. For example, in patients with myocardial infarction, the periphery of the repair scar is composed of reactive fibrosis and hypertrophic cardiomyocytes surrounding the scar area.
Regarding the great harm of myocardial fibrosis, you can directly refer to Xiao Shugang as an example.
Let's talk about this pathological section. There are large areas of myocardial fibrosis, and almost nothing else is seen. It is really rare. The pathology of patients with myocardial infarction many days later will still show a little granulation tissue at the edge.
"It's possible that the location of it is not right." Teacher Yuan Fang said.
When making pathological sections, you must select appropriate lesions. If the location is not accurate, it may not represent the pathological characteristics of the entire human organ. What Teacher Yuan Fang said makes sense.
What Cao Yudong needs to correct is: "What you said is possible. But if not, we may need to consider other causes and diagnoses."
All aspects should be taken into consideration when discussing.
In fact, most heart diseases are caused by the pathological characteristics of myocardial fibrosis. Looking back at the examples of myocardial fibrosis patients, almost all types of heart disease patients are covered.
Here’s some trivia: patients including drowning may develop myocardial fibrosis.
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