In the evening, Zhao Yuan met Xu Qin in the office.
I haven't seen my senior sister for a while, and Xu Qin has lost a lot of weight.
It's not that I'm sickly thin, but that through long-term fitness, my whole person's temperament has become more sunny and confident, and my body line has become smooth and soft.
Xu Qin took out a paper from his bag and handed it to Zhao Yuan.
"I discussed the idea you proposed last time with Master Zhu and then revised it. This is the final draft. Take a look at it. If there are no problems, I will submit it tomorrow."
Zhao Yuan took the manuscript in his hand and read it carefully. There were many changes. In addition to the core points, the entire structure was revised, making it appear more professional and rigorous, and enhance its persuasiveness.
Sometimes whether a paper can impress the judges depends on its rigor.
Zhao Yuan’s advantage lies in his forward thinking, but he wrote relatively few papers and the structure must be adjusted.
"It's very well written. Why didn't you and Master Zhu's names be signed?" Zhao Yuan was a little surprised.
Xu Qin said with a smile, "I just did the polishing work, and there is nothing of mine in the article. For Master Zhu, she thinks that her participation in the entire article is too low. In addition, this is your first article
Articles in foreign core journals signed with her name will reduce your contribution."
Zhao Yuan secretly thought that Zhu Haixia was careful enough.
Many tutors see the students below writing good papers and want to take advantage of them.
Zhu Haixia is obviously much more advanced, and she values the growth of her students more.
This paper by Zhao Yuan mainly describes car-t technology.
CAR-T is called chimeric antigen T cell immunotherapy.
By culturing T cells in vitro that can kill cancer cells and transporting the T cells back into the patient's body, therapeutic effects can be achieved.
Clinically, this technology is used to treat blood diseases such as multiple myeloma, acute lymphoblastic leukemia, and refractory malignant lymphoma.
In addition, it also has certain therapeutic effects on some solid cancer diseases such as neuroblastoma and glioma.
This concept was proposed at the end of the last century, and its development process in this world is very slow.
If we count the time, in the past five years, there has been a major breakthrough in another world.
However, in this world, there has never been a breakthrough point.
Many blood teams across the country are working hard to capture the breakthrough.
This paper by Zhao Yuan mainly provides a breakthrough idea on how to prepare car-t cells in large batches!
Currently, the cells approved for CAR-T cell therapy and used in clinical trials are all from autologous sources.
That is, T cells are collected from the patient, modified outside the body to recognize targets on the surface of cancer cells, and then reinjected into the patient.
However, this personalized process is complex, time-consuming and expensive, greatly limiting the number of patients who can benefit from CAR-T therapy.
In his paper, Zhao Yuan proposed using allogeneic cells to produce "off-the-shelf" CAR-T cells, eliminating the need for personalized preparation processes.
This enables ready-made cell therapies to be provided to more patients faster, more reliably and on a larger scale.
To put it simply and straightforwardly.
In the laboratory, it has been proven that car-t can treat diseases, but it cannot be mass-produced.
Zhao Principle gave the idea of mass production.
The theoretical knowledge in the laboratory can be directly transformed into results that can be used in market operations.
It's like a serum for treating snake venom.
In the beginning, in the laboratory, there was a way to create a one-to-one snake venom serum, but there was no way to create a serum that could treat many snake venoms.
The production cost of one-to-one snake venom serum is too high and mass production is not possible.
But with the advancement of technology, the laboratory has developed a serum that can treat many snake venoms, which can be mass-produced. Once produced, it will have market value.
Because Zhao Yuan knew that in another world, the mass production idea he proposed was feasible, he felt more confident in writing the paper.
When Xu Qin first came into contact with Zhao Yuan's idea, he was immediately shocked.
Zhao Yuan has only recently come into contact with the relevant knowledge of hematology.
Everyone knows that his advantage lies in clinical surgery.
Although hematology also involves surgery, it is completely different from the system that Zhao Yuan is good at.
Facts have proved that Zhao Yuan has extraordinary imagination and creativity in research on blood diseases.
Zhao Yuan’s entry point is linked to practicality.
This paper can provide accurate ideas to many teams.
Zhu Haixia has already intended to carry out fruitful research on Zhao Yuan's point of view.
Zhao Yuan actually did not have much confidence in this paper, mainly due to his lack of understanding of blood diseases.
However, with the improvement of Xu Qin and Zhu Haixia, the paper showed a unique effect.
Xu Qin said with a smile, "Master Zhu told me privately that with your thesis, you can directly graduate with a Ph.D."
Zhao Yuan was surprised, "Don't lie to me. Master Zhu is just giving me encouragement. Don't you still know what I have in my belly?"
Xu Qin's tone was sincere, "Don't be modest. You have only been practicing in this field for more than a year, and you can write such an in-depth paper. To be honest, you are really a genius in scientific research. If you hadn't done such a good job in surgery, I guess Zhu
The teacher will definitely drag you into the laboratory every day to squeeze more things out of your head."
Zhao Yuan's scalp went numb when he heard this, and he said with a guilty conscience, "I'm really not good at scientific research. Master Zhu must have noticed that I had a sudden flash of inspiration."
Xu Qin looked at Zhao Yuan with a smile, "By the way, I'm hungry."
Zhao Yuan patted his forehead and said, "I'll treat you to dinner! Tell me, what do you want to eat?"
Xu Qin frowned, "There is no sincerity at all. Do you know what is the most correct way to treat guests? You should not ask what to eat, but choose a good place and take me there directly."
Zhao Yuan burst into laughter, "Let's eat our own food!"
Xu Qin stood up, her beautiful eyes moving, "Well, this attitude is pretty much the same."
Zhao Yuan didn't know where Senior Sister Xu was from, but he felt that Senior Sister Xu's temperament was like that of a girl from the south of the Yangtze River. She was somewhat refined and fashionable, soft on the outside but strong on the inside, and loved to compete in everything she did.
If you are in a relationship, this kind of personality is a must-have. If you make a small mistake, she will have a cold war with you for half a month.
But when it comes to scientific research, this personality is very suitable, and you will have enough toughness when encountering tough problems.
Xu Qin's personality is similar to that of Zhu Haixia when they were young, so they have a very good relationship, not only as master and apprentice, but more like mother and daughter.
The decoration of the restaurant is good, and with the elegant melody, it feels like being on the Bund.
The vegetables are stir-fried in a light and refreshing way, and the fish is cooked in heavy oil and red sauce.
Halfway through the meal, Xu Qin finally explained another reason for looking for Zhao Yuan.
"Junior brother, I have something to ask you for help."
Zhao Yuan put down his chopsticks and said with a smile, "Your business is my business, no need to be polite, just give me orders!"
