The so-called drug targets refer to biological macromolecules that have pharmacodynamic functions in the body and can be acted upon by drugs.
Involving receptors, enzymes, ion channels, transporters, immune system, genes, etc.
It is a link that must be involved in general new drug research and development.
For example, the well-known panobinostat developed by Novartis can treat multiple myeloma, and its drug targets are REP tyrosine kinase and histone deacetylase.
Drug targets can conduct certain research on certain diseases faster and more accurately, thereby developing new drugs with better efficacy and fewer side effects.
From the 20th century to the 21st century, human drug research and development has crossed over from the chemical model to the biological model. That is, the target-based drug discovery model has replaced the traditional medicinal chemistry discovery model and has become the mainstream model of modern drug research and development.
If the drug target of a new drug can be found, the subsequent research and development process will be much smoother. Many pharmaceutical companies and research institutions face difficulties in this step.
And if a drug target can be known, many pharmaceutical companies with some financial strength are eager to come and buy the information about the target.
After all, they can develop new drugs. Once the research and development is successful, they will make more money than they will lose.
But can technology and innovation really be bought with money at any time?
Mr. Lu Xun has long told us that only your own things are reliable. Anything that uses money to pave the way is always the research result of others, not your own wealth.
After Fang Mu returned home, his wife saw that his face was a little sad, so she asked with concern:
"What's wrong? You look sad."
Fang Mu told her about Xu Li's invitation today.
"Tell me, what should I choose? Should I continue to live my current life or choose to take another risk?"
After hearing this, the wife just smiled and said:
"No matter what you do, I will support you. As long as you think your choice is right, then go ahead, even if it has many thorns."
"Besides, they say you can live a long life, but a person's life only lasts for a few decades. Just do something without regrets."
After listening to his wife's words, Fang Mu was silent for a long time.
Then he started eating, bathing and sleeping as usual, but he thought about it for a long time that night before finally making a decision.
Pick up that business card...
The Spring Festival passes quickly.
During this period, my mother only visited her grandparents, and then she didn’t visit any other relatives.
After all, visiting relatives is also troublesome, running back and forth, but now that my mother has a serious job in the cafeteria, she has not gone this year. The same goes for my father, who is inspecting water and electricity maintenance on campus.
Basically, he doesn’t have to worry about campus water and electricity maintenance.
In the past, campus water and electricity were outsourced to companies, but now since Xu Li took out the water purification technology from the Science and Technology Library and established Qinglan Sanitation, the contract has been terminated.
The water supply is basically managed by the family, and the electricity is handled by the local Fengcheng Power Grid. However, for related maintenance, it is enough for my father to organize a team to perform regular maintenance.
Xu Li has basically been staying in the laboratory of Shennong Pharmaceutical these days..
It's almost a life between two o'clock and one line, but Xu's mother often whispers on the phone.
But while he was in the laboratory, a strange phone call came in.
"Wai? Hello, who are you?"
"It's me, Mr. Xu, Fang Mu."
Xu Li was stunned after hearing this.
"It turns out to be Dr. Fang. Have you thought about it?"
"Yes, I decided... to give it a try, but the premise is that if the information you provide is not true, then I will leave immediately!"
"Haha! Don't worry, I don't have the time to lie to you. Of course, once you join, I will also give you generous treatment. How about a tentative annual salary of 1.5 million?"
"Of course...as long as you can support your family."
"Then you can come over at any time, and I will have someone help you arrange a dormitory as soon as possible."
"Okay."
After hanging up the phone, Xu Li directly summoned the tool man Xiaobai.
"Xiao Bai, you will arrange an apartment dormitory later. It will be a suite, a single room. Dr. Fang Mu will join us soon."
Anyway, Shennong Pharmaceutical has no shortage of dormitories. After some rectifications, some problematic leaders, executives and employees were fired.
These vacant rooms also have similar suites and serve as staff dormitories.
"Okay, I'll make arrangements immediately."
Xiaobai just nodded and left.
"Having said that, although the target of this drug has been found, the subsequent clinical trials still need to be handled by Fang Mu."
After all, he is good at finding things, but clinical trials are about medicine, not semiconductors, but about human health, so it is better to be cautious and let professionals come to help faster.
Within a few days, Fang Mu arrived at Shennong Medicine with his suitcase. After putting his suitcase in the dormitory room, he was called by Xu Li.
"Dr. Fang, I'm sorry to call you in such a hurry. In fact, my anti-cancer drug has found the corresponding drug target, but the next clinical trial requires the help of professionals like you."
Fang Mu was shocked when he heard what Xu Li said.
Drug target found?
So fast?
No, even if there is a drug prescription, if it is a targeted drug, the drug target still needs to be found during the experiment. It takes a long time, and the result tells him that he has found it.
This...
"Let me see!"
Fang Mu came to the instrument, and after some testing, it turned out to be the drug target that Xu Li said.
He looked at Xu Li strangely. Could this guy be hiding something?
Even if he were to find a drug target, it would be impossible to find it in such a short period of time.
But now that it has been found, it is a good thing. At least the subsequent research and development and clinical trials will be smoother.
"Boss, if possible, I would like to start animal testing as soon as possible and then clinical trials."
Fang Mu felt a little excited, which meant that domestic anti-cancer drugs could be developed as soon as possible.
"I understand, but it is estimated that it will take three days for the employees to return to the company to work normally. Why don't you get familiar with them in the past two days?"
Xu Li thought that the employees of Shennong Pharmaceutical were still on vacation and might not be back soon.
"I understand. Let me get familiar with the environment here in the past two days."
Fang Mu nodded.
Then, he and Xu Li formally established a contract relationship, including the salary and benefits previously discussed, and he was considered an official Suiren employee.
Xu Li also told Ma Xingming about Fang Mu.
Three days later, the first group of people to return to the company were the R&D personnel.
Ma Xingming introduced them to Fang Mu and the laboratory director who was about to serve as the drug research and development department.
Fang Mu also announced the drug plan they developed this time to the researchers in the R&D Department.