Laboratory synthesis of compounds and large-scale industrial production are two different things.
Aldrich felt that there was not enough manpower, so he brought in an Irish chemist named Gene Corey. Together they established the "Aldrich-Cory Laboratory", with research funds provided by Zhou Hexuan, who was responsible for the research and development of sulfa drugs.
Research and development, and the industrial preparation method of dapsamide.
Since the structure of dapsamide is not complicated, the two quickly found multiple ways to prepare it. The key now is which way is the most efficient.
After repeated experiments, Aldrich and Corey basically determined the direction. That is to directly sulfonate acetanilide and excess chlorosulfonic acid to synthesize the intermediate product p-acetamidobenzenesulfonyl chloride, thereby completing the large-scale development of p-aminosulfonamide.
Production on scale.
This is the most traditional and original industrial production method of sulfonamide, which has low efficiency, high consumption, large pollution, and a large amount of waste acid will be produced during the production process. If Zhou Hexuan used this method to produce sulfonamide, then the second largest royal park in the UK (British Royal Park) would be destroyed.
Park) will be turned into a mess, and even the nearby Hampton Court Palace (known as the British Palace of Versailles) will be affected.
When a large amount of industrial waste acid is discharged into the Thames River, there will inevitably be countless dead fish floating in this British mother river, and the river water will be colorful and beautiful.
What is environmental protection?
Today there is no concept of environmental protection at all. Factory chimneys are a symbol of civilization, and industrial wastewater is the culprit of civilization. Zhou Hexuan is happy to contribute to British civilization.
"Mr. Zhou, this is the sulfonamide production process I designed." Gene Corey handed Zhou Hexuan a drawing.
Zhou Hexuan asked: "With this set of machines, can we produce sulfonamides on a large scale?"
Gene Corey explained: "This is just a preliminary idea. Whether it is realistic and whether problems will arise, we still need to do experiments and debugging slowly. You'd better find a mechanical engineer who will improve the machine and design it."
Production line.”
"Understood," Zhou Hexuan said to Ornish, "Mr. Hartley, this job will be left to you."
Ornis smiled and said: "No problem, I will look for the best mechanical engineer."
Ornish is now very ambitious. Although he has not been exposed to the pharmaceutical industry, he has rich business experience. He firmly believes that he will become prosperous and become a significant entrepreneur in the UK.
In the laboratory, Aldrich and Corey continued to be busy, while Zhou Hexuan left the University of London with Ornish.
"Zhou, are you going back to China soon?" Ornish asked.
Zhou Hexuan nodded and said: "Yes, I have been in England for three months, and it's time to go back."
"What about Mary?" Ornish's role has changed from partner to father.
Vivien Leigh is Ornish's only daughter. She has been doted on since she was a child and can be described as docile. Ornish spent a lot of effort in raising her daughter. She hired people to teach Vivien Leigh violin, piano and other musical instruments since she was a child. She let her daughter perform on the stage at the age of 3.
She also sent her daughter to study in various European countries, so that Vivien Leigh can now speak four languages: English, French, Italian and Spanish.
Vivien Leigh said last year that she wanted to become a movie star, and Ornish immediately gave her full support. He asked his friends to establish connections and spent a lot of money to send his daughter to study at the Royal College of Art.
Although Ornish is not a competent husband, he is definitely a competent father.
"I heard that you have a wife in China?" Ornis asked, obviously he had inquired quietly.
Zhou Hexuan nodded and said: "Yes."
Ornish said bluntly: "Zhou, I hope you can divorce your current wife and then marry my daughter."
"I'm afraid this is a bit difficult." Zhou Hexuan said.
"Then you are playing with Mary's feelings!" Ornis said displeased.
Zhou Hexuan said with some embarrassment: "Mr. Hartley, you have lived in the East for many years, so you should have some understanding of Eastern customs. Chinese people can marry concubines, and I want to marry your daughter as a concubine."
Ornish said angrily: "Zhou, I have already asked someone to inquire. Chinese concubines are not protected by law at all, and they are not much different from Western lovers!"
"Although the law does not protect it, society recognizes it," Zhou Hexuan argued.
Ornis emphasized: "A couple that is not protected by the law is not a real couple!"
Zhou Hexuan suddenly said: "Can legal couples protected by the law love each other for a lifetime?"
"Uh..." Ornis was suddenly speechless. He was a man who had divorced his wife.
Zhou Hexuan continued: "Mr. Hartley, I promise to always protect and care for your daughter. I will hand over the management of the pharmaceutical factory to you and invite you to become a shareholder. This is the best proof. What do you think?"
The first half of the sentence is nonsense, and a man's commitment to love is simply unreliable. The second half of the sentence is the key point. If Ornish wants to make a breakthrough in his career, he must choose to cooperate with Zhou Hexuan, because the patent for sulfonamide is in the hands of Zhou Hexuan.
.
Do you want a daughter or a career?
Ornis felt very confused.
In Ornish's moral concept, he believes that it is normal for a man to have several lovers. If Zhou Hexuan marries his daughter, he will accept it even if he secretly keeps seven or eight mistresses. But the premise is that his daughter must be his official wife.
Because it’s not safe to just throw away this lover thing, and it would be embarrassing to say it out.
Ornis had difficulty making a decision. He said to the driver with a headache: "Go to the Royal College of Art!"
Zhou Hexuan smiled like a fox.
Since the hit performance of "Titanic", Vivien Leigh has become a big star in London. She often attracts crowds at the Royal Academy of Arts and receives countless love letters every day. She basically attends classes during the day and performs in the theater at night.
and take time to rehearse on weekends.
Although she was so tired every day that she didn't even have time to have a tryst with Zhou Hexuan, Vivien Leigh never tired of it and felt that her life was extremely fulfilling. She liked this kind of life.
Zhou Hexuan and Ornis drove to the school, and after waiting for only a moment, they saw Vivien Leigh coming out of the campus and walking towards the special car arranged for her by the theater.
"Mary, this way!" Ornis waved and called.
Zhou Hexuan stuck his head out, smiled and waved to Vivien Leigh.
When Vivien Leigh saw her sweetheart coming with her father, she immediately waved happily. She ran to the special car and said a few words to the driver, then jumped into Zhou Hexuan's car with joy and said happily: "Dad, Xuan, why are you here?"
Already?"
Ornish said: "I stopped by to pick you up."
"Let's go eat first." Zhou Hexuan hugged Vivien Leigh's slender waist.
Vivien Leigh leaned into Zhou Hexuan's arms and took the initiative to give her a sweet kiss. The two of them started kissing passionately in the back seat of the car.
Ornis was sitting in the passenger seat, looking at the intimate scene in the rearview mirror, and was so angry that he could not speak. His daughter was already fascinated by this oriental man, and nothing he said would work. Ornis felt that he had raised his daughter in vain.
19 years.
"Shet!" Ornis cursed in a low voice and told the driver to drive quickly.
