"Dr. Sun, this is Xiao Linfeng." Before Sun Lien could speak, he heard Xiao Linfeng say on the other end of the phone, "I am now with Mr. Aaron, the senior vice president of Shire Pharmaceuticals. This call is hands-free.
of."
"Mr. Xiaolin, we need some help." Sun Lien had no time to ask why the phone was on speakerphone. He said directly, "Our hospital admitted a patient who developed symptoms of malignant hyperthermia during the operation. Our hospital does not
Reserve dantrolene, a specific drug for the treatment of malignant hyperthermia. Does your company have similar products? Can you provide us with some urgently?"
"Dantrolene is a drug produced by an American company, and our company has not been involved in related fields." Kobayashi Feng first rejected Sun Lien's request, and then asked pretending to be curious, "Dantrolene has been out for many years, is it expensive?"
Why doesn’t the hospital have any reserves?”
Sun Lien sighed, "This drug is not produced in China, and it has not passed cfda certification. Even if you go through the green channel, it will take more than two years for a batch of drugs to arrive and be reviewed. The drug storage validity period is only three years.
They are basically useless in China. These drugs are expensive to import, and hospitals cannot afford to spend a lot of money to store drugs that are about to expire."
"Many orphan drugs are like this. Due to the influence of some processes and regulations, they cannot immediately enter the mainland market for sale. This is not conducive to drug research and development companies to recover their research and development costs." Xiao Linfeng followed Sun Lien's words, but there seemed to be some prefaces.
No follow-up words. "Speaking of which, Dr. Sun, is this the first rare case you have encountered?"
"I may have been unlucky recently." Sun Lien smiled awkwardly on the other end of the phone. "Although our hospital is a large emergency center, emergency patients from nearby areas are sent here. But there are indeed a lot of them recently."
"I don't think so." Kobayashi smiled and said, "With the advancement of medicine, the incidence rate of many so-called rare diseases is actually much higher than we imagined. It's just that these patients have not been diagnosed before, or doctors do not know enough about these diseases.
There are many, so it may have been misdiagnosed as other diseases.”
"As for the medicines you need, I will ask our Greater China manager to contact you directly and do our best to provide medicines for your hospital." Xiao Linfeng changed the topic, "But after all, this medicine is not a product of our company.
I can’t guarantee that we can provide it in time. But I assure you that everyone in our company will do their best.”
Sun Lien was overjoyed when he heard this, "Thank you so much, Mr. Xiaolin."
After hanging up the phone, Xiao Linfeng looked at Aaron with a smile, "Mr. Aaron, as you have heard, the sales of drugs for rare diseases have great potential in the Chinese market!"
"Just relying on a phone call cannot explain the problem, Mr. Kobayashi." Aaron spoke with a sense of arrogance unique to Western social elites. "It is easy to arrange for an actor to call at a specific moment.
Isn’t that what happened?”
"Of course I can arrange actors, but an actor can't do these things." Xiao Linfeng smiled slightly. He knew these self-esteemed Westerners too well. He glanced at his secretary, who looked at him respectfully.
I took out a stack of printed documents from my bag.
"These are the summaries of all the patients of the 'actor' you just heard about in the past month." Xiao Linfeng spent a lot of money to bribe Zhao Weihua in order to have the ability to make a decisive blow at this time. "I can guarantee that.
The authenticity of these documents, you can see how many rare diseases a doctor diagnosed in a Chinese hospital in a month."
Aaron flipped through the record perfunctorily at first, then his face gradually became serious, and the speed of reading the case became slower and slower.
"You have to know that the emergency department of this hospital alone can treat more than 200,000 people every year." Xiao Linfeng struck while the iron was hot and continued, "There are six other hospitals of the same level in the city of Ningyuan." He
Looking at Aaron, he leaned forward and said with some excitement, "Think about it, Mr. Aaron. In one city, there are more than 1.2 million doctors in a year! How many people are there in Dublin? Two million? Three hundred
Thousands? There are hundreds of cities of the same size or even larger size in China! Those patients, those patients, those markets!"
"I...we can carry out experiments of the same scale in India..." Beads of sweat flowed from Aaron's head. He also wanted to win more benefits for himself and the company's shareholders. He insisted, "The Indian government
There are no restrictions on us conducting clinical trials..."
"What's the price? Mr. Aaron?" Xiao Linfeng looked at Aaron with a half-smile, "Your company has never launched clinical trials in India since its establishment. The reason is that everyone knows that once clinical trials are started in India, Indian pharmaceutical companies will
You will definitely be able to obtain the synthesis method of experimental drugs, and you can produce large-scale imitation products. The market for your company's products is already very small. If it attracts competition from Indian pharmaceutical companies, you will no longer be able to sustain it, right?"
"Not to mention the Indian market. The number of patients who can afford the high price of your company's products is very small, and most of them live in Europe or the United States. They also live in India and need to rely on the local medical system for treatment.
The crowd has almost no ability to pay." Xiao Linfeng moved forward, "So, opening up the Indian market will not benefit you at all, except that your products will face challenges. But China is different."
Kobayashi waved his hand fiercely, "Chinese people are much richer than Indians. And they will pay for sick family members on a family basis. More importantly, China's attitude towards rare disease drug policy has changed.
."
"Now that they have changed, we can enter the Chinese market ourselves." Aaron was almost unable to refute. He wiped the sweat from his head and said with a smile on his neck, "China welcomes foreign investment to build factories, and we can invest directly.
!”
"Then what?" Yutaka Kobayashi sat back and asked with a smile, "Set up a factory in China and you will promote the medicine bit by bit? With all due respect, Mr. Aaron. If there is no promotion by a large pharmaceutical group similar to Takeda, how can you
It is impossible to apply for clinical trials. If your drug cannot be included in the payment list of social insurance or commercial insurance, it will still be a dead end." He smiled and waved his hand, "Do you want the Chinese market? Then sign up
Let’s sign the contract. 64 billion US dollars and the full support of Takeda Pharmaceuticals. Believe me, we are very sincere.”
"How is it?" Cao Xin listened to Sun Lien hang up the phone and asked anxiously, "Is there any medicine?"
"Takeda Pharmaceutical said that dantrolene is produced by an American company, and they have not been involved in related fields. But they will fully support helping to find drugs." Sun Lien showed a look of helplessness, "The problem is, even Takeda's president said that he dare not Ensure that the medicine can be found in time.”
Dr. Cao scratched his head angrily, "This is troublesome." Without dantrolene, it means that the patient's temperature can only be controlled by physical means. Patients with temperatures of 38, 9 or even 40 degrees are okay. , But for a disease like malignant fever that can reach 45 or 6 degrees Celsius, it’s hard to say how effective ice blankets and the like can be.
"We will try our best to do what we can, and the rest will only depend on whether the patient's life is good or not." Sun Lien sighed. He thought about it and made another call.
Shen Qingmei was in a meeting. She was shocked when she saw the call on her mobile phone. She didn't care about the many executives sitting in the conference room. She picked up her mobile phone and walked out of the conference room.
"Doctor Sun?" Her voice was trembling, "Is...is something wrong?"
Only then did Sun Lien realize what Shen Qingmei was worried about, and quickly explained, "Chen Wen is fine, don't worry. I'm calling now to ask for your help."
Knowing that everything was fine with her baby daughter, Shen Qingmei breathed a sigh of relief. After hearing about Sun Lien's search for medicine, she pondered for a moment and asked, "I may have a way to find the medicine, but... are you sure it can be used?" Is it on the patient?"
Sun Lien replied with some confusion, "It should be... okay? This is a special medicine. If it is not available, the patient's condition will be very dangerous."
"Dr. Sun, you haven't read the news for a long time, right?" Shen Qingmei sighed, "Some time ago, a doctor got into big trouble because he introduced foreign generic drugs to his patients."
Sun Lien covered the phone and repeated Shen Qingmei's words to Cao Xin, then asked, "Brother Cao, do you know about this?"
"There's nothing to worry about." Cao Xin glanced at Sun Li'en and said, "Dean Song is here to take care of it. Besides, this is considered an emergency. The family members have already approved it, so there's no problem."
Sun Lien nodded and conveyed Cao Xin's words to Shen Qingmei. "Mr. Shen, human life is at stake. Please forgive me."
"Okay." Shen Qingmei was about to hang up when she suddenly asked out of nowhere, "Have you contacted Takeda Pharmaceutical about this drug?"
"I just spoke with Mr. Feng Xiaolin." Sun Lien replied honestly, "He is meeting with Mr. Aaron, the senior vice president of Shire Pharmaceuticals."
Shen Qingmei was shocked when she heard this and quickly asked, "When did it start?"
"I don't know." Sun Lien scratched his head, "But when I called just now, Xiao Linfeng was talking to me on speakerphone."
Hands-free? Shen Qingmei grasped the key point. "Did you mention during the call that it is difficult for drugs for orphan diseases to enter the Chinese market?"
Sun Lien looked around, made sure Shen Qingmei was not nearby, and said confusedly, "That's right..."
"Dr. Sun, this medicine is packed with me!" Shen Qingmei replied with a smile, "This news is very important to me, thank you!"
After hanging up the phone, Shen Qingmei walked into the conference room with a whirring sound. She waved fiercely at the many executives in the conference room, "The acquisition negotiations between Takeda Pharmaceuticals and Shire Pharmaceuticals have entered the final stage. Takeda has come up with The bargaining chip is the Chinese market..." She glanced around at her senior executives, "No need to discuss it anymore, the financial services department will follow up immediately, and each subsidiary must allocate 60% of existing funds to the financial services department within three days. ." She made a decision with high spirits, "I, Yuhua, must take a big bite of Takeda's fat meat!"
Shen Qingmei is a very decisive woman. Only fifteen minutes later, Sun Lien received a call. Danquluolin, who was anxious to save people, was found. The Macao Red Cross Society forwarded two copies of Danquluolin to the Mainland Red Cross Society through green channels. Pack Dantrolene, and a Yuhua Group charter flight will take off directly from Macau to deliver this life-saving medicine to Ningyuan. The plane is preparing to take off and is expected to arrive at Ningyuan International Airport in two hours and thirty minutes.
"Great." Dr. Cao breathed a sigh of relief. As long as dantrolene is available, the patient's mortality rate can be directly reduced from 75% to about 5%. Although it is still dangerous, at least the chance of survival is greatly increased. He breathed a sigh of relief, then patted Sun Lien on the shoulder and said, "I'm really sorry to trouble you."
Using personal relationships for free because of strangers' affairs is a taboo for other people in society. But for doctors, this action does not need to be considered at all. If you trouble others, you can save a life, even if you owe it to yourself It’s also very cost-effective to exchange favors.
Dr. Cao and Sun Lien hurriedly said a few more words, and then immediately left the ninth clinic. Although the operating room has been notified, it is of positive significance for the patient to end the operation as soon as possible and switch to comprehensive physical cooling. Now is not a surgery. When the junior fellow student increases his knowledge, Dr. Cao must rush to the operating room immediately to assist the chief surgeon in completing the operation as soon as possible.
Sun Lien stretched his arms, and then saw the new patient triage information on the screen. He pressed the call button and said to the small microphone on the table, "Li Lifen, patient Li Lifen please come to the ninth clinic."
A woman with a sallow face walked in. She showed a timid smile towards Sun Lien.
"Hello." Sun Lien lowered his head to find a pen and prepared to take notes. He asked without raising his head, "What's wrong with you?"
"I, I want to prescribe some painkillers." Li Lifen whispered, "I have a toothache."
Sun Lien looked up and saw a series of status bars displayed above Li Lifen's head, "Li Lifen, female, 57 years old, mild myocardial infarction, mild starvation ketosis."
Anyway, now that he saw the word "infarction", Sun Lien broke into a cold sweat, and this time was no exception. He looked at Li Lifen's face, looked up and down for a while, and then asked cautiously, "You just feel like you have a toothache? What's wrong? Are there any other symptoms?”
"I..." Li Lifen seemed to want to say something, but in the end she shook her head. "I just have a toothache. Doctor, please be kind and give me some painkillers."
Mild starvation ketosis means that Li Lifen is unable to eat enough for a long time. This symptom, which should be extinct in theory in modern China, is now common in cities. Many young women who have long-term excessive dieting in order to lose weight have this reason. Suffering from a disease. But Li Lifen does not look like the kind of person who would lose weight for the sake of body shape. The status bar does not indicate an eating disorder. I am afraid that her hunger ketosis is really due to insufficient food.
Sun Lien asked tentatively, "What did you eat at night?"
Li Lifen was stunned for a moment, then she said covertly, "I ate, I ate a lot. I ate meat, rice, potatoes..." As she spoke, a look of pain appeared on her face, "Doctor, just give it to me. Prescribe some medicine."
If it weren't for the status bar, Sun Lien would have thought that Li Lifen might be addicted to painkillers. He lowered his head and wrote a few words in his notebook, thinking quickly, then raised his head and said, "Open the painkillers." The medicine is fine, but I need to give you an electrocardiogram first." Mild starvation ketosis will not affect your life immediately, but myocardial infarction is different. Sun Lien decided to solve the most urgent problem first.
"I..." Li Lifen seemed to want to refuse, but Sun Lien immediately interrupted, "The cost of the examination is included in the outpatient service. Let's go, I will accompany you for an examination. Don't worry, the electrocardiogram will not hurt at all, and
The results are also very fast. As soon as the test results come out, I will prescribe painkillers for you, okay?" He coaxed and deceived Li Lifen out of the ninth clinic, and then walked towards the emergency room.