The word "catastrophic" in the name of catastrophic antiphospholipid syndrome has clearly demonstrated the catastrophic power of this disease. Compared with ordinary antiphospholipid syndrome, catastrophic antiphospholipid syndrome
The onset characteristics are not the same. Generally, antiphospholipid syndrome is mainly characterized by large blood vessel thrombosis, the disease progresses slowly, and generally does not involve multiple organs.
But catastrophic antiphospholipid syndrome is completely different. It is a serious disease with a clinical mortality rate of more than 50%. It involves more than three organs within a week of onset, and also contains arterial and venous thrombosis, and the main manifestation is microvascular thrombosis. The patient finally died
Most die from pulmonary embolism or DIC symptoms caused by abnormal coagulation.
The most frightening thing is that there is currently no ideal treatment for catastrophic antiphospholipid syndrome.
"If it's caps, that would be terrible." Yuan Pingan's face was as heavy as iron, and he said to Sun Li'en, "The patient has just received thrombolytic and anticoagulant treatment, but his small intestinal ischemic necrosis has not been completely reversed. If necrosis
If the area continues to expand, resection surgery will have to be performed at the risk of intraoperative bleeding."
"Compared with the risk of small intestinal necrosis, this risk is completely acceptable." Dr. Pascal is not too worried about this. "Let's do an apl antibody test first. Diagnose caps, and then start hormone shock and immunosuppressive treatment immediately, and then supplement
Use plasma exchange. This can control antibody aggregation in the shortest time and reduce the risk of abnormal coagulation without heparinization. As long as the plasma replacement is timely enough, he should be able to safely undergo surgical treatment."
The treatment plan proposed by Dr. Pascal is the standard response. For the current situation, this is the only thing the doctors can do for Xia Hongyuan.
"Let's issue a serious illness notice." Sun Lien sighed. He really didn't want to see this situation. A teacher who was loved by students, a young and energetic first-level athlete, was now lying in the emergency room.
He was dying. Even if he had undergone surgery to remove the blood clot and received thrombolytic treatment, his chance of survival was still 50-50.
How could Sun Lien feel relaxed in this situation?
"I'm going to talk to the family." Seeing Yuan Pingan bring the notice of serious illness, Sun Lien stood up and took the notice, turned to Dr. Pascal and said, "After the family agrees, treatment will begin immediately."
Sun Lien left the most difficult work to himself.
Xia Hongyuan's parents had been waiting outside the door for four hours. Their only son had already undergone an operation. However, seeing the doctors as if they were in danger, Xia Hongyuan's parents could not figure out why the doctors were so nervous. Finished
After the operation, shouldn't the child gradually get better?
"Doctor Sun!" Xia Hongyuan's father saw Sun Lien from a distance. He quickly stood up, walked forward and asked, "How is he doing?"
Sun Lien looked around with some embarrassment. This was the rescue hall, and there were many people nearby. He whispered, "His current condition is quite stable. Please come with me first, together with your wife. This is not the place to talk about things."
"
Xia Hongyuan's father's heart suddenly sank, and he tried his best to hold his wife's hand. But the uncontrollable trembling all over his body could be seen as long as he was not blind.
Sun Lien sighed softly and led the two of them to the small conference room.
Dr. Pascal originally thought that Sun Lien would take the parents to other conference rooms, but he did not expect that he would bring them directly here. Looking at the ashen middle-aged couple opposite, Dr. Pascal also sighed and stood up.
I found two paper cups and poured some tea into them.
"Please sit down, these are all colleagues in our treatment team." Sun Lien asked the two of them to sit down, and then handed over the serious illness notice he had been holding in his hand. "This serious illness notice, please
You two sign it."
A large puddle of water suddenly came out of the water cup that Xia Hongyuan's father had just picked up, "What's going on?"
Sun Lien sighed again. "As you two know, we have already performed surgery on Xia Hongyuan. However, his problem is not just the part that our surgery can solve." He pointed to the patient with symptoms written all over it.
The sequential whiteboard said, "Xia Hongyuan's disease caused all of these symptoms, and based on the information we currently have, we believe that the name of this disease is 'catastrophic antiphospholipid syndrome'."
"You mean... you are not completely sure yet?" Xia Hongyuan's father was keenly aware of the problem in this statement.
"We are still waiting for the final conclusive examination evidence." Sun Lien replied, "But based on the current situation, the possibility of this disease is the highest."
Xia Hongyuan's father was silent for a moment and then asked, "If this is the disease, how should it be treated?"
"Let me explain this part." Sun Lien was about to speak, but Dr. Pascal stood up. "This is my professional content."
"I am a doctor in the Department of Rheumatology and Immunology, Pascal." Dr. Pascal briefly introduced himself to the parents, "According to our diagnosis, the disease that Xia Hongyuan suffers from is a relatively rare autoimmune disease, and
The main characteristic of this disease is abnormal coagulation in blood vessels throughout the body."
"First of all, we still cannot determine the cause of this disease. But according to research, trauma may be the main factor in triggering this severe reaction. But considering his previous experience as a professional athlete, we have no way to narrow it down to a specific event.
Trauma." Dr. Pascal's voice was very calm and sounded slower than his usual speaking speed. "But the onset of his disease was very insidious, and not many organs were involved at first." He pointed to the whiteboard.
"The first organ affected should be the small intestine." Dr. Pascal looked at Xia Hongyuan's mother who was already crying with some sympathy, "That is to say, you received a call from him before, saying that you had an upset stomach.
when."
"Later, he was sent to the hospital with severe pain all over his body. We currently believe that it was caused by a blood clot in his brain." Dr. Pascal continued to explain, "The blood clot should not be large, so he
He did not show severe symptoms of stroke, but showed unexplained pain."
"After entering the hospital, we first alleviated his pain symptoms." The next part is what Xia Hongyuan's parents knew, but Dr. Pascal's explanation was still very detailed. "And we immediately recalled Dr. Sun," he pointed out.
He pointed at Sun Lien, who was listening attentively to the side, and complimented him a little, "He is the leader of our treatment group, and he is also the doctor with the best diagnostic technology."
Of course, Lao Pa's praise was not to flatter Sun Li'en, but to ease the mood of the two of them. Knowing that the doctors who treat his children are of high quality can indeed relieve the pressure of many patients' families.
"After many tests, we gradually locked his disease on the current 'caps'." Dr. Pascal said a lot before continuing, "Because considering the severity of this disease,
So we issued a critical illness notification to you."
Sun Lien did the rest. "First of all, let me tell you that Xia Hongyuan's disease is very dangerous."