After learning that four firefighters were unfortunately poisoned while performing their duties, Liu Tangchun immediately rushed to the rescue room to make arrangements.
Unlike other types of patients, acute organophosphorus inhalation poisoning can cause very serious respiratory system and nerve damage. After organophosphorus enters the blood through the lungs, it will inhibit acetylcholinesterase in the human body. And acetylcholinesterase
Its main function is to degrade acetylcholine.
Acetylcholine is a special substance that mainly acts on several special nervous systems of the human body. The sweat gland secretion nerves that control sweat secretion, all parasympathetic nerves, sympathetic preganglionic fibers, etc. transmit information through acetylcholine. And acetylcholine
The role of esterase is to terminate these signal transmissions at the appropriate time.
The degradation function of acetylcholinesterase is directly terminated under the interference of organophosphorus. Acetylcholine is flooded in the nerves, and the secreted concentration is still rising. It will eventually trigger systemic choline nerve excitement, and the result of excessive excitement is only
One line is exhausted.
The main cause of death in organophosphorus poisoning is respiratory failure and coma caused by excessive nervous excitement. To rescue people from poisoning symptoms, we first need to get out of the toxic environment, and then immediately use anticholinergic drugs to help the body hydrolyze the nervous system.
Too much acetylcholine.
The drug of choice for clinical rescue of organophosphorus poisoning is atropine.
Atropine is usually used in rescue operations to relieve visceral colic, including gastrointestinal spasms, as well as sinus bradycardia and atrioventricular transmission obstruction. Atropine extracted from belladonna or datura can block the cholinergic nerve's response to acetylcholine.
reaction, thereby preventing cholinergic nerves from being overexcited.
The reason why Liu Tangchun made a special trip to the emergency room to arrange work was because of a reason that left people speechless.
The dosage of atropine injection produced by pharmaceutical factories is too small now. The common atropine injection specification is 0.5mg/1ml. In order to achieve the blocking effect, a patient needs at least 400mg of atropine per hour, which means at least 800 bottles of atropine.
Injections are enough.
Large-dose atropine injections have not been produced for many years. Atropine is usually used clinically mainly for its anticonvulsant effect. Large-dose atropine injections do not seem to be necessary. After all, there are too few cases of organophosphorus poisoning.
"All nurses who can leave their posts, and all residents who have no patients on hand, all gather at the nurses' desk!" Director Liu shouted at the top of his lungs in the emergency room, "Come and break the ampoules!"
The door to the rescue room was pushed open, and a blue flat trolley was pushed in by the pharmacy staff. "Director Liu, the atropine injection you want, there are five boxes here, totaling 2,500."
Sun Lien was shocked by this number.
"It's not enough, hurry up and move it." Urging the pharmacy to continue delivering medicine, Director Liu asked the nurse to give each of the doctors present a 100-ml syringe. "You all know how to open an ampoule, so I won't talk nonsense."
Come on. Hurry up, the helicopter is expected to arrive at the helipad in six minutes. Before then, we have to gather atropine for at least four people!"
The orderly organizational structure in the emergency room of the Fourth Central Hospital began to take effect. The senior nurses suddenly transformed into shepherd dogs and began to drive the residents in white coats to cooperate with each other. Every day
A nurse managed three residents at the same time. They used scissors to quickly knock off the heads of the ampoules in their hands. The opened ampoules came in groups of five and were quickly stuffed into the hands of the residents. The injection was carefully inhaled.
into the syringe, and then threw the opened ampoule on the spot in the empty box. Next, the second and third groups opened the bottles and inhaled the medicine.
Sun Li'en and Xu Yourong did not join this team. The hands of neurosurgeons need to be protected. The rough work of breaking ampoules is not suitable for Xu Yourong, but Sun Li'en was summoned by Director Liu.
"Go to the pharmacy immediately and find Han Wenping, the director of the pharmacy department." Liu Tangchun called Sun Lien, "Tell him that I need at least 10,000 more atropine here. I don't care if he steals, robs, or simply goes to the pharmaceutical factory.
Moving the warehouse, I have to see the medicine within an hour, do you understand?!"
Sun Lien was about to go out when he suddenly heard Liu Tangchun shouting from behind him, "Tell Han Wenping that this is Dean Song's order!"
Dean Song Wen has indeed issued an order. She received a call directly from the municipal party committee two minutes ago. Long Xinsheng, secretary-general of the municipal party committee, made a direct request on the other end of the phone, "At all costs, do our best, we must cure the disease."
Well done to these four heroic firefighters."
The call ended quickly. When it was about to end, Secretary-General Long specially emphasized it again, "We must not let the heroes bleed and shed tears. We must use the best measures and the most advanced means!"
The one who is under the greatest pressure in the entire hospital now is Dean Song Wen who received the call. When she answered the phone, Liu Tangchun happened to be reporting on the progress of the emergency response mechanism in the president's office. Deputy Director Liu was arrested by his own director and the president.
A strong man.
"Director Han, I am Sun Lien from the emergency department." Sun Lien opened the door of the pharmacy. Inside, a group of pharmacists were moving boxes in the storage room. In order to facilitate their work, these doctors, who were not very strong at first, even took off their shirts.
, shirtless, running back and forth among the shelves.
After asking several people in succession, Sun Lien finally found Han Wenping, the shirtless director of the pharmacy department, who was moving boxes in the deepest part of the pharmacy.
"Director Liu said that the current dose of atropine is still not enough. We must get more than 10,000 atropine doses within two hours!" In order to better preserve the medicinal materials, the temperature in the reserve warehouse is always maintained at about 8 degrees. Director Han is a bald head.
, the naked head was floating upwards in the warehouse with hot steam. When you reach middle age, you will inevitably have a beer belly, but Director Han’s upper body muscle lines are still quite conspicuous. He looks like he can beat at least five Sun Lien.
"Aren't I looking for some medicine?" Director Han wiped the sweat from his head and cursed, "Four organophosphorus poisonings! Last year I said that I had low atropine, but no one believed me.
!”
Sun Lien did not dare to get involved in the war of words between these directors. He was just faithfully performing his duties as a messenger. "Director Liu said, whether you are stealing, strong, or simply moving the warehouse of the pharmaceutical factory, atropine must be
Delivered." After a slight pause, Sun Lien continued, "Director Liu said that this is also what Dean Song meant."