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Chapter 99 Acute methamphetamine poisoning

Meth is the common name for amphetamine or methamphetamine. This substance derived from ephedrine hydrochloride is also called "amphetamine" together with Ritalin and dextroamphetamine.

Different from ordinary opioid tranquilizers, amphetamine is a powerful central nervous system stimulant. It can stimulate neurons in the locus coeruleus, striatum and other parts of the human brain. This can lead to increased involuntary movements and excitement in the human body.

Behaviors such as stereotyped movements, irritability, mental changes, and even self-mutilation may occur.

This kind of central stimulant was widely used in the military field during World War II. A large number of soldiers became excited after taking amphetamines and were not afraid of death. They did not need to rest, and they did not even need logistics. After taking amphetamines, the effect of the drug would be

Suppress appetite.

During World War II, apart from the United States, amphetamines were widely used as military stimulants in Germany and Japan, the country where amphetamines were invented. In 1920, Japanese chemist Aso Kata first synthesized methamphetamine using ephedrine.

Japan's technology for extracting amphetamines from ephedrine has advanced rapidly. The concentration of the extracted finished product can reach almost 100%. Japanese expatriates who mastered this technology and immigrated to Hawaii discovered a large demand for methamphetamine in the United States, especially in the United States.

After further tightening of methamphetamine control in the mid-1980s, large amounts of underground homemade methamphetamine began to appear.

Under the control of local gangs, these products flowed into the United States. At the same time, the methods of manufacturing methamphetamine were also introduced to the central United States, Mexico and other places. Due to the relatively relaxed attitude of the Western world towards drugs, a more serious epidemic has occurred.

Drug abuse problem.

This is why there have been reported cases similar to Gao Yan in Hawaii. In a few cases of acute poisoning caused by methamphetamine (abbreviated as MA), there will be high fever, extremely high creatine kinase, and high cerebrospinal fluid pressure.

, grass-green urine. At the same time, people who abuse stimulants or tranquilizers generally become resistant to anesthesia. When the dose is low, they are unable to effectively anesthetize and relieve pain. When the dose is high, they are more likely to have adverse reactions than ordinary people.

However, the Fourth Central Hospital did not have the means to test whether urine contained methamphetamine metabolites. Although the Provincial Occupational Disease Prevention and Control Hospital had such technology, the test results came out too slowly. Only then did Sun Lien pay attention.

Arrive at the police station.

Unlike the Western world, China can be said to be the country with the strictest attitude towards drugs. Grassroots police stations are basically equipped with rapid test strips, a test artifact used to combat drug abuse.

The quick test paper can test whether the person being tested has used drugs in the past two weeks, and if it is more than two weeks, it can be checked through hair. Judging from Gao Yan's illness, he should have taken drugs about a week ago. It happened to be

Within the detection range of the quick test paper.

"Test paper?" Old Wu put down the rag in his hand and said warily, "Yes, yes, what do you want this for?"

"The knife wound that was delivered today, I suspect may have been caused by methamphetamine." It is also part of the doctor's job to report drug addicts discovered to the police. Sun Lien has no other ideas about how to punish Gao Yan for drug abuse.

He just wanted to diagnose the condition quickly and save his life. He was just 21 years old, and there should be many possibilities for his life. It was a pity to die like this on the bed in the emergency room of the hospital.

"Meth?" Old Wu nodded thoughtfully, "Just wait a minute, I'll look for it."

The police room at the entrance of the Fourth Central Hospital is not large, about 20 square meters. In addition to office supplies, it mainly contains several sets of steel forks, transparent shields and helmets used to control people. It was not originally

The large police room suddenly seemed a little cramped. Old Wu bent down and searched around the police room, and finally took out a small cardboard box from the drawer. However, he did not hand the reagent to Sun Lien.

Put it in his pocket. "Let's go, I'll go with you."

Lao Wu had a law enforcement recorder hanging next to his shoulder and followed Sun Lien all the way to the ICU. Considering that law enforcement might be obstructed, Lao Wu did not say hello to Gao Yan's parents who were waiting outside, but walked in first.

In the ICU, I asked the nurse on duty for an unused paper cup. Lao Wu squatted down skillfully and released a little grass-green urine from Gao Yan's urine bag. Then he did an experiment with a test strip.

Five minutes later, a clear horizontal line appeared on channel C on the test paper. It was confirmed to be a positive reaction. After Lao Wu took a photo of the reaction with a law enforcement recorder, he said to Sun Li'en, "What should I do? Can this patient's condition be stabilized?

?”

Ignoring the ICU nurse's look, Sun Lien was quickly notifying Xu Yourong via WeChat. While sending the WeChat message, he shook his head and said, "It's hard to say, he's been poisoned for a long time. Let's go to treatment first and give him a cure."

"

As expected, Gao Yan's parents vehemently denied the fact that their son had used methamphetamine. The old couple looked at Sun Lien with eyes full of shock and resentment. If they hadn't seen Lao Wu in police uniform, they would have been put on the spot.

He would come up and give Sun Lien a good beating to relieve his grievances.

However, the prompts of the quick test do exist, and the symptoms of high severity are indeed consistent with the characteristics of acute methamphetamine poisoning. Although the quick test may have false positives, after comprehensive consideration, it is most appropriate to treat acute poisoning now.

method.

"Adjust the treatment plan." Sun Lien has never dealt with acute methamphetamine poisoning, but Xu Yourong may have seen more OD (overdose, overdose) patients during her internship in the United States than Sun Lien has seen emergency patients. She adjusted skillfully

Xu Yourong's plan was crude and direct, "Two grams of vitamin C, mixed with 200 ml of glucose. Infuse once every 12 hours. Increase the total amount of fluid rehydration and inject it according to the standard of 8 liters per day." Xu Yourong's plan was rough and direct, "Every two

Inject 200 ml of mannitol intravenously every hour to wake up his kidneys."

No matter what kind of poisoning it is, removing the toxins from the body as soon as possible is the first method of treatment. Vomiting when people eat spoiled food is a naturally evolved method of eliminating toxins. But now it is obviously meaningless to ask Gao Yan to get up from the bed and vomit.

Methamphetamine is not taken orally, and it has been too long. All doctors can do now is to speed up the metabolism in Gao Yan's body and make his kidneys work hard in the hope of expelling as much poison from his body as possible.

substance.


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