Bai Ye booked a ticket for tomorrow. After meeting his instructor that day, he went to visit the masters of traditional Chinese medicine and Mr. Tu.
They helped Bai Ye a lot, so since he arrived in Kyoto, he couldn't lose his courtesy.
The next day, after packing up and paying homage, we returned to Shanxi.
In the past few days, Bai Ye and Meng Yunxi had chatted several times, each time just a few words, but they missed each other because they were busy.
The two were more familiar with each other than before. At least Meng Yunxi would not ask Bai Ye, "Who are you?", and could even make a little joke occasionally. But what made Bai Ye embarrassed was that every time the topic of mice came up,
The other party got busy and asked him to consider discussing the issue formally another day.
However, Bai Ye now has a lot of things on his shoulders and doesn't have much time.
After returning to school, I tidied myself up and went to the library the next day with my notebook and schoolbag on my back.
The library on this day is much cleaner than before. It is neither an exam month nor a preparation period for postgraduate entrance exams. Everyone is crazy about exuding youthful hormones in the spring of May. Only people like Bai Ye who commit themselves to study can do so.
Come to the library.
Bai Ye's purpose in coming to the library was very simple, just to give Keao a satisfactory answer.
I now have a level of lv6 in statistics, and the data has been further improved. It won't take long before I can calculate the results of this data!
Bai Ye also wanted to know what went wrong. If the data was intentionally mutilated, what was the other party's purpose?
The first part of the data is still a record of the conception of the experiment and the process of transcription and replication of single-cell organisms.
The data records the differentiation of single-cell organisms after carcinogenesis, as well as changes in the original nucleic acid structure, and whether there is a deliberate reduction in the probability of single-cell biomolecules causing cancer.
This process is relatively complicated. First, the carcinogenicity of different organisms must be compared under the same carcinogenic conditions.
Then find a single-celled organism and continuously change the mutation points in DNA and RNA transcription and translation. After finding it, change the sequence and observe whether the carcinogenic rate can be effectively reduced.
This is the core of the experiment.
Bai Ye began to recalculate. The original data only had a ratio of single-celled organisms, and it was not perfect. Their elimination standards were very strict. Any experimental steps that had a slight variation would be eliminated from the observation group.
In this way, after being invisible, the number of cases is reduced, but the success rate of the experiment is also increased.
Bai Ye's data was calculated on all cases, and he also included those data that could have been included in the inclusion criteria.
The huge amount of data forced Bai Ye to concentrate on calculations, so Bai Ye simply turned off his phone and devoted himself to analysis.
Time went very quickly. Two days later, Bai Ye finished calculating the first set of data!
However, it was discovered that not all changes to DNA and RNA sequences can affect the risk of cancer.
Only certain single-celled organisms can really affect the probability of carcinogenesis. Therefore, changing a certain sequence may not be applicable to all single-celled organisms.
However, there is a single-celled organism that can significantly reduce it!
That’s the data from the experiment a few days ago!
What does it mean?
Changing that sequence will only really work for a certain type of single-celled organism!
The data in the first part has a conclusion. The data is correct and the conclusion is correct.
Bai Ye continued to study the second part, which was to model cancer-causing mice that form digestive tract tumors.
Then, by injecting drugs, the nucleic acid structure of the tumor cells is changed to observe whether the proliferation of tumor cells can be effectively suppressed.
The km mice are used. The advantages of this kind of mice are obvious, such as fast fecundity, fast growth, strong disease resistance and adaptability. They are widely used in pharmacology, toxicology, microbial research and effect experiments of drugs and biological products.
and safety evaluation.
And in recent years, it has become widespread in cancer.
There are more than 20,000 cases of cancer-causing mice, and Bai Ye is also a bit confused. After all, there are so many mice, and it is difficult to analyze them.
And in order to better compare the efficacy, he added the imatinib group, oxaliplatin group, blank group, placebo group...
The current directions of tumor treatment have all joined the ranks of comparison.
The calculation process is more troublesome, but it is just troublesome.
Bai Ye was not afraid of trouble. He spent a whole day and the A4 papers in his hand piled up into a small mountain.
Hundreds of sheets of scratch paper filled with writing and drawings seem to be discarded every minute.
Sunday was the fourth day Bai Ye arrived at the library.
Calculated the result!
An unexpected result surprised Bai Ye, p=0.05!
What does it mean?
The feeling of being neither up nor down is very embarrassing!
If p < 0.05, it is generally considered to be a small probability event. If it is less than 5 times out of 100, it can be considered to have no impact. However, if it is less than 0.05, it means that the hypothesis is not established, and the difference is statistically significant!
It means that the experiment should be established!
However, the boundary value of 0.05 does not represent a small probability. It is very likely that it is 100% possible and 100% impossible!
How did things get back to this point?
What does it mean?
To put it bluntly, this experiment can actually be proven to be successful!
It can be proved that this drug is indeed better than other drugs and more effective than those anti-tumor drugs on the market!
But!
Is it really?
Bai Ye was a little suspicious. If that was the case, why was there a missing data in the first place?
Where is the data missing?
So here’s the problem!
Then, Bai Ye suddenly remembered the original data. As long as he found the original data and compared it, he would know where it was missing.
Then through calculation, we can definitely get the reason!
You will know the result by then!
Thinking of this, Bai Ye quickly stood up, packed up his things and left the library.
Back in the dormitory, Duan Yue was playing games, while Lu Peiyi was on the phone. Fatty was not around. I haven't seen this guy much these days, and I don't know what he is busy with.
Bai Ye picked up the mobile hard drive and walked towards the library. After all, the situation in the dormitory... was really not suitable for research.
Bai Ye didn't mean to blame them. After all, in a collective dormitory, you couldn't ask for too much.
Back in the library, Bai Ye couldn't wait to connect to the computer, open the hard drive, and compare the data!
There was too much data, and comparison was not a simple task. Bai Ye was dazzled by it!
It took nearly an entire afternoon to finally get the results!
Compared with the original data, only one piece of data is lost!