Helan's jumping incident not only did not increase negative impact on Puze, but instead brought him a good reputation bonus.
As for the subsequent development of things, Bai Ye didn't pay much attention to it because Chang Lili asked for leave and took annual leave in advance. Plus sick leave, she may have to take a period of rest.
Maybe Helan's incident had some big or small impact on her, so Helan submitted an application, and the leader quickly approved it.
The director of the fifteenth-floor department is called Zhao Xiaojun. He used to be the deputy director under Jiao Liming. Later, after the mental health department was established, Zhao Xiaojun became the director. Therefore, Zhao Xiaojun has always respected Jiao Liming.
After Chang Lili rested, Zhao Xiaojun found Bai Ye and asked him if he was interested in staying in the department for a while. Bai Ye did not refuse and decisively agreed.
Because during this time on the fifteenth floor, I had a lot of feelings for Bai Ye, and I even had a lot of feelings about Bai Ye's future medical career.
If the body is sick, it can be adjusted by regulating the body, but if the mind is sick, how to treat it?
Bai Ye began to ponder this question continuously.
Among the diseases on the fifteenth level, the two most common are depression and anxiety. In fact, these two are completely different diseases, and both their manifestations and treatments start from two completely opposite directions.
Depression is a common mental illness with long-term low mood as the main clinical feature. The symptoms are often inconsistent with the environment. The clinical manifestations are mostly depressed mood. In severe cases, it may be grief-stricken or even stupor.
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Moreover, the terrible thing about this disease is that once depression occurs, it is easy to relapse, but each episode can be relieved in most cases. In some cases, it will leave sequelae or become a chronic disease.
Depression can be caused by many reasons, but it is often accompanied by loss of interest, low mood, self-blame, guilt, lack of self-confidence, loss of energy, poor sleep, and loss of appetite.
At least 10% of patients with depression will experience manic episodes, which is the so-called bipolar disorder. Some patients have significant anxiety and motor agitation, and severe patients may experience psychotic symptoms such as hallucinations.
According to statistics, 2% of patients with depression have suicidal thoughts, the suicide rate of patients with severe depression is as high as 10% to 15%, and 30% to 70% of suicide deaths are related to depression.
So, with such a high fatality rate, can any other disease compare with it?
Anxiety disorder is also a common mental illness whose main symptoms are unpleasantness and pain, often accompanied by physical discomfort. 3.66% to 28.8% of people suffer from this disease throughout their lives, and more than 90% of patients develop the disease before they are 10 years old.
, women tend to have more anxiety disorders than men.
Although depression and anxiety are two different mental illnesses, they often appear clinically at the same time and have many of the same clinical symptoms, including poor sleep, loss of appetite, loss of energy, and irritability.
When depression and anxiety disorders coexist, it is called comorbid depression and anxiety disorder in clinical diagnosis. It is one of the most common forms of comorbidity in psychiatric clinics. Research shows that 60% to 90% of patients with depression also have comorbidity.
Anxiety symptoms, and more than 50% of patients with depression also have anxiety disorders that meet the diagnostic criteria.
Why is anxiety called anxiety disorder? Because most anxious patients will have a feeling of physical disorder. This feeling will make people feel uncomfortable all over. Some people are flustered, but there is no problem with the electrocardiogram. The cardiac color ultrasound shows that this is
Normal people's heart function. Some people feel short of breath and wheezing, but their lungs are very good and their respiratory tract is very normal, etc...
Anxiety disorders are accompanied by a variety of discomforts, and this disease is like a brain problem that controls discomfort in various parts of the body.
Moreover, there is no reason or solution for this discomfort!
Bai Ye didn't believe this. He felt that there must be something that controlled the spiritual emotions of the human body. There would be some kind of dynamically balanced substance in the human body. This substance would control human emotions, anger, sorrow, joy, sorrow, and fear.
Wait for all kinds of emotions.
It’s just that this kind of thing has still not been discovered!
If the body is sick, it can be treated, but if the heart is sick, how to treat it?
This is like a terminal disease that afflicts all kinds of people.
Suppose your friend has a certain disease, such as pneumonia, fracture, etc. When others ask you, you may be generous and generous, but if it is a mental illness, you may be embarrassed to say it.
Bai Ye now has a sense of mission. He feels that he should work hard to study the mechanisms of these diseases and then solve this problem.
Because these diseases are so harmful!
He is not only hurting himself, he is constantly affecting others, and even the society.
Research has found that: The impact of depression and anxiety on others and society. Depression and anxiety disorders will have a significant impact on an individual's physical and mental health, work level, social ability and physical activity. Patients have a low evaluation of their own physical health, and some
The patient's various social functions and physical mobility are reduced, which will cause damage to many social functions, causing problems such as the inability to work normally, marital discord, and parent-child relationships.
The impact of depression and anxiety on life and health. One of the common symptoms of patients with depression and anxiety is suicidal behavior, which will cause great harm to themselves and their families. Even if they attempt suicide, they will cause harm to their own bodies, and there is the possibility of repeated suicides.
.Deaths due to depression and anxiety and suicide have become a major cause of death in the population.
and!
This disease is hereditary!
Yes, he will inherit it. Research has found that the occurrence of depression and anxiety is closely related to heredity. The probability of the same disease among relatives is much higher than that of the general population, which is 8 to 8 times that of the general population. The closer the blood relationship, the more consistent the onset of the disease.
The higher the sex, such as parents, brothers, and direct relatives of children, the incidence concordance can reach 12% to 24%, dizygotic twins are 12% to 38%, monozygotic twins are 69% to 95%, and cousins are 2.5%.
%.
Other data show that the role of genetic factors increases with age. Current research has not fully revealed the specific inheritance mode of depression. The expression of abnormal genes or the inability to express normal genes is the mechanism that causes most mental diseases.
The combination of genetic patterns, environmental and psychological factors often affects the occurrence of depression, and most depression and anxiety disorders are polygenic hereditary diseases.
Bai Ye feels that since this is a hereditary disease, there must be a substance that is constantly changing human genes. This will form a genetic structure that changes the genetic structure and forms a hereditary disease.
result.
Therefore, after wanting to understand this, Bai Ye began to make preparations.
Every day, Bai Ye gets up early and stays up late at night. He consults various documents to study what caused this change.
During this period, Zhao Xiaojun also began to receive patients one after another. It has to be said that after truly understanding the patients and going through clinical trials before reading books, he gained more and made faster progress.
During this time, Bai Ye put aside all the things around him and spent the whole day studying the causes and treatment options for anxiety disorders and depression.
At this time, time is always merciless and flies by in the blink of an eye, but Bai Ye, after clinical testing, discovered several things that are currently monitored and related to anxiety and depression.
From a biochemical perspective, possible factors mainly include 5-hydroxytryptamine (5-ht), norepinephrine (norepinephrine, ne), dopamine, acetylcholine and aminobutyric acid, etc.
These five indicators are directly related to anxiety and depression in the human body. Currently, various drugs are treated based on these five biochemical components.
However, these examinations are extremely expensive. This is not a simple test and blood draw. It is extremely expensive to monitor these human substances.
However, if we really want to treat thoroughly and achieve good results, we must study the true levels of these five indicators in each person's body.
If you want to study this thoroughly, the next thing you need to do is to start with these five indicators, survey every inpatient, then score the patient's symptoms, conduct meta-statistical analysis, and analyze the research results.
Only by thoroughly researching these things can the treatment be based on symptomatic treatment.
After thinking about it clearly, Bai Ye felt that he should take this matter as his graduate project.
But before that, Bai Ye checked all the cases on the computer in the past ten years since the department was built on the 14th floor. These cases were all cases of patients treated since the establishment of the psychiatric department.
Every hospitalized patient has a hospitalization case, and these cases are valuable research data.
Puze Hospital has popularized computerized medical records less than ten years ago, but the psychiatric department on the 15th floor has been established for a long time. Many patients' medical records are in handwritten versions. To find out, it is necessary to study historical cases.
So Bai Ye found the medical record room, where the hospital's 20 years of cases were sealed.
Every patient has a medical record. After discharge, the paper version of the medical record will be sent to the medical record room, and the hospital will keep it for twenty years. Within these twenty years, patients can use their identity information to copy and investigate the medical records.
At the same time, doctors can also investigate cases for research.
However, the latter is relatively rare. Many cases of patients after discharge are shelved by doctors and will not be studied at all.
Because many doctors have been reduced to working hard and have lost the instinct to think.
But Bai Ye is not like this. He knows the importance of these things. These are countless research experiments and data, which are very detailed. Each case is a very comprehensive research data.
Bai Ye spent half a month, running to the medical records room every day when he was free, to compile all the data he needed.
Finally, he sorted out the data and conducted various statistical analyses.
During this time, Bai Ye can be said to have devoted himself wholeheartedly to it.
Finally, Bai Ye came up with a conclusion about the treatment method for anxiety and depression on the 15th floor of Puze Hospital.
Medication remains the mainstay of treatment for depression.
He found that no matter how rapidly antidepressants develop and how many varieties and types they increase, they can only be divided into two types of heterocyclic antidepressants, tricyclic and tetracyclic, based on their chemical structure.
Tricyclics are classic antidepressants. They are currently mainly divided according to their mechanism of action, mainly including selective 5-ht and reuptake inhibitors (such as venlafaxine); selective 5-ht reuptake inhibitors (such as fluorine
cetin); selective reuptake inhibitors (e.g., reboxetine); selective 5-ht reuptake activators (e.g., tianeptine); ne and specific 5-ht reuptake antidepressants (e.g., mirtazapine)
); 5-ht balancing antidepressants (such as trazodone); and dopamine reuptake inhibitors (such as bupropion); reversible monoamine oxidase inhibitors (such as moclobemide), etc.
In addition, traditional Chinese medicines are gradually accepted by the majority of patients due to their mild effects and few adverse reactions, such as Hypericum perforatum, Acorus calamus, Bupleurum, Ginkgo, ginseng, Centella asiatica, grapefruit, Inner Mongolian astragalus, Albizia julibrissin, etc.
Antidepressant effect. Therefore, studying the antidepressant effect of traditional Chinese medicine and its prescriptions has great potential and is of great social significance in treating the increasing number of patients with depression.
However, these drugs can only temporarily alleviate and suppress the development of the disease, but cannot cure it!
…………………………
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It's already September, and it's time to prepare for graduation projects.
Although he did not explicitly ask him to prepare a proposal report, he also told everyone that they should start preparing for this matter.
When Bai Ye found his mentor, Liu Boli was sitting in the office reading.
At his age and stage, it is no longer necessary to spend time in the hospital every day, but this stubborn old man comes to his place of work on time every day, whether in the outpatient department or in the office, he is very punctual.
Seeing Bai Ye come in, Liu Boli closed the book. Bai Ye rarely came to see him, but every time he came, there was something serious.
"Hello, teacher." Bai Ye bowed.
Liu Boli nodded: "Sit down, what's the matter? What do you want from me?"
He asked straight to the point. In fact, he was very satisfied with himself as a student, who always brought him unexpected joy from time to time. Wherever he went, it could be said that there were great changes!
The Anorectal Department has transformed from a general department into a regional diagnosis and treatment center, a national key specialty, and a national anorectal demonstration site.
Just a few days after I went to the 14th floor last month, the two directors of the acupuncture department and the encephalology department were alarmed. The facial paralysis recovery acupuncture was very effective, and they directly established a facial paralysis recovery center.
Wang Wenliang was also very clever. He took advantage of this opportunity and directly applied for the project. It is estimated that the National Natural Science Foundation of China will not have to run away this time.
If the research is thorough and this facial paralysis rehabilitation clinic develops into a facial paralysis rehabilitation center, everything will fall into place and it will not be a problem at all.
The encephalology department is no different from other departments. It was originally a key specialty. Now its development has reached a bottleneck. Every step is very difficult. However, these bottlenecks seem to not exist at Bai Ye. He can break them with just a small operation.
.
This kid is really a gift from God to Puze!
No, it should be a gift to Chinese medicine.
Liu Boli suddenly remembered that when Zhao Xiaojun met him, he said that Bai Ye had gone to the fifteenth floor and had been following him on the fifteenth floor for some time.
According to my own understanding of this boy...
Could it be...
Thinking of this, Liu Boli suddenly became energetic. Could it be that Bai Ye had any special views or ideas about the mental health department?
After the idea came to him, he could no longer control his well-controlled heart rate...
Liu Boli took a deep breath. He felt that when chatting with Bai Ye, he should adjust his breathing and heartbeat, so that he could not be surprised at all changes.
Bai Ye couldn't help but feel uneasy when he saw Mr. Liu looking at him calmly.
"Teacher, it's like this. I discovered in the psychiatry department that the current treatment methods for depression and anxiety disorders are somewhat inappropriate."
“Through extensive review of various materials, I found that from a biochemical perspective, the possible factors affecting the development of the disease mainly include 5-hydroxytryptamine (5-ht) and norepinephrine (ne)
, dopamine, acetylcholine and aminobutyric acid."
“Although many studies in recent years have supported the 5-ht hypothesis, studies have shown that 5-ht is directly or indirectly involved in regulating people’s mood. Decreased 5-ht levels are related to depression, while increased 5-ht levels are related to mania;
However, many studies have reported that the occurrence of depression is related to the content and regulation of ne, dopamine, acetylcholine, aminobutyric acid, etc. More research work is needed to truly reveal the biochemical mechanisms of depression and anxiety."
"Then I collected and analyzed the main methods and analysis of our hospital's treatment of the disease over the years, and came to the conclusion..."
After Bai Ye finished telling what he had done recently, he turned to Liu Boli: