Intense scientific research work, rigorous scientific research attitudes, down-to-earth scientific researchers, and an orderly atmosphere are carried out in this small scientific research institute.
Bai Ye is the person in charge and the boss here, and he is also just one of the ordinary employees here!
Similarly, every scientific researcher here is working hard, hoping to gain something and make a breakthrough.
There are various industries involved in scientific research, including computers, IT, and the Internet, which are all familiar and lucrative industries.
Materials science, engineering, aerospace...these are all high-end industries that are not very clear.
The field of bioengineering is a unique industry.
The "Alloy Project" has been going smoothly for nearly a month. During this month, everyone has conducted various investigations and explorations.
If you want to prove that cobalt-chromium alloy can increase the content of trace elements such as cobalt and chromium in the human body, you must do the following things!
The first is the census!
Conduct a census of trace elements in people who have had alloy prostheses implanted. Kyoto City has a population of tens of millions, and there are many people with prostheses in their bodies. What is the significance of the census?
It is to obtain a relatively common information through large sample statistics, and to obtain a census conclusion through data analysis.
The number of people is small, there is no point!
However, the measurement of trace elements costs a lot of money. Bai Ye teamed up with seven or eight testing companies and studios in Kyoto to specifically test the collected patient information.
In one month, 30 million yuan was spent on inspections!
The second is material science analysis, analyzing the adverse effects of trace elements such as cobalt and chromium on the human body, and investigating positive indications in patients with excessive amounts of these trace elements.
Research on trace elements has never stopped, but how high is the positive rate of these reactions in the human body?
This needs to be investigated!
Now that he has obtained the spom company's outsourcing project, Bai Ye is now confident that he will receive the US$600 million!
Moreover, not only must it be taken, but it must be held beautifully!
Therefore, the second thing is to improve the probability investigation of the positive manifestations of trace elements in humans and obtain a clear adverse reaction rate.
The third one is what Bai Ye is currently studying!
How does the material cobalt chromium affect the human body, thereby causing symptoms of anxiety and depression?
This is the hardest!
It is also the most technical research, and it is also what Bai Ye is most interested in.
The first thing Bai Ye and the animal experiment team did was animal simulation experiments, constructing animal models, and detecting changes in various substances in rats by studying excess cobalt and chromium trace elements.
In order to detect the levels of norepinephrine and dopamine, Bai Ye specially purchased a testing company for 20 million.
The experimental research was carried out in an orderly manner, and the division of labor and cooperation between the various groups was very orderly.
During the National Day holiday in October, people across the country are enjoying this seven-day holiday, either traveling or resting at home, while the entire scientific research team is spending time in long experiments.
And on this day, the 6th, the first group of studies had a result!
An article was published in Puze Hospital's newspaper "Puze Latest Medicine".
"Study results of positive complications in 10,000 patients with cobalt-chromium alloy prostheses in Kyoto City"
This is a big data census of 10,000 people. It investigates, follows up and analyzes 10,000 patients in Kyoto who have had cobalt-chromium alloy materials implanted in the human body. Through the follow-up data and analysis results, a conclusion is reached!
Cobalt-chromium alloy prostheses can cause many adverse effects. Although cobalt-chromium alloys are highly corrosion-resistant, they ignored one of the most important factors during research, which is the ionized environmental factors of the human body and the long-term dynamic balance of the human body.
state, rather than a stable fixed environment.
In such a dynamic equilibrium, one of the most common manifestations will appear, the ionization reaction.
When the ionization reaction occurs, the two substances cobalt and chromium will undergo trace ionization in the human body.
Produces cobalt-chromium metal ions, which are highly toxic!
Indeed, among the alloy materials currently in use, cobalt-chromium alloy is the most common and one of the most useful materials.
In the latest resistance research results, the Vickers hardness of titanium alloy is 600, the bending strength is 600, and the elastic modulus is only 120, while the Vickers hardness of cobalt-chromium alloy material is as high as 1000, the bending strength is also 1000, and the elastic modulus is 230, basically
Each of the above data is more than twice that of titanium alloy.
This is a disparity in comparison!
The most common and commonly used cobalt-chromium alloy in clinical practice is mainly in the field of hip joints. There are 1 to 2 million patients undergoing hip replacement surgery in the world every year. What kind of performance will occur in such a large proportion?
This is hard to imagine!
In a census of 10,000 people, the results showed that 8% of the patients had experienced gastrointestinal adverse reactions, which could not be cured by ordinary oral drugs. 9% of the patients had experienced orthopedic
Complications: After joint replacement surgery, bone degeneration occurs, and long-term wear and tear has a significant erosion effect on the bones in the contact segment.
If you switch to this kind of medicine for a long time, a very common situation will occur, which is the symptoms of cobalt chromium ion poisoning and the occurrence of anxiety disorders in patients.
Among them, Bai Ye cited thousands of completed case follow-up forms of anxiety disorder patients in Puze. After conducting a meta-analysis, he obtained the cobalt-chromium alloy composition of human prostheses, which can increase the risk of anxiety disorders.
factor.
The journal was published immediately and instantly entered the eyes of many people around the world.
The current impact factor of "Puze Latest Medicine" is as high as eight points, and it is already a famous medical journal in the world. This journal often publishes some new materials and information, which often arouses the interest of the world's academic circles.
Especially in the fields of orthopedics, anorectal medicine, and emergency medicine, "Puze Latest Medicine" has become a relatively famous magazine in these three disciplines.
Many people will choose to subscribe!
Therefore, when this article about a large-scale survey of follow-up data for 10,000 people was published, it immediately caused an uproar!
When everyone saw this piece of data, they all frowned. In the field of science, nothing is more convincing than data.
But when they saw the data results, everyone was confused: Is this a joke?
This is not a joke, and the joke is not funny at all.
This is a big deal!
If this report is really effective in reporting such a thing, it is very likely that it will trigger a series of chain reactions that no one can imagine.