Ferno Medical Group has twelve group subsidiaries, but the largest one is Hankison Company, which mainly focuses on orthopedic medical equipment.
As a listed company, the market value of Ferno Group has exceeded 150 billion U.S. dollars. As one of the top 100 medical groups in the world, it ranks eighth in the medical circle.
The first place is Johnson & Johnson, the second is UnitedHealth, and the third is Pfizer.
Hankison's 30-storey office building is located in Detroit, USA, and today Hankison's company is holding a monthly meeting.
Pierce is the general manager of Hankison. As the general manager of Fenno, he is independently responsible for Hankison's daily affairs and operations.
Pierce is in a good mood. Last year, Hankison did a good job in expanding his business and accounted for 40% of the entire Ferno Group in terms of profit growth.
"Shouldn't everyone express their opinions?"
Pierce is not a dictatorial person. As a general manager, he is very good at listening to everyone's suggestions.
The person in charge of the marketing department said: "At present, in terms of structural adjustment in the second half of the year, I suggest that we can focus slightly on the direction of hip and knee prostheses. The market returns in the first half of the year..."
The meeting went smoothly and was about to end.
Miller, the person in charge of academic research, hesitated again and again, then stood up and said, "Maybe before the meeting ends, I have something I want to talk to you about."
Pierce smiled: "It seems that our meeting today will not be too boring. Dr. Miller, the good news should have been shared earlier."
Pierce thought Miller had discovered something new.
Miller took out a journal, stood up and said: "This is a journal from China called "Pu Ze Latest Medicine". He recently published an article called "10,000 Cases of Cobalt Chromium Implantation in Kyoto City"
Study results of positive complications in patients with alloy prostheses.”
"This article is about the complications that have occurred in patients with cobalt-chromium alloy prostheses within ten years. It describes some of the shortcomings and shortcomings of cobalt-chromium alloys. The most important thing is about the hidden dangers of inducing anxiety disorders.
, if this matter is true, it may affect the sales of cobalt-chromium alloy prostheses.”
Pierce curiously took the magazine and read it carefully. After reading it, he asked: "How is the influence of this journal?"
Miller: "Puze Latest Medicine has been established for a long time and has a good status in the country. However, it only entered the sci database at the beginning of this year, and the person in charge of the journal is the author of this article: Bai Ye."
When the word Bai Ye was spoken, everyone present was startled.
Because in the field of orthopedics, Bai Ye still has some considerable influence, especially the incident of treating Cruise in Los Angeles, which was even more heated at the time.
Pierce frowned: "Bai Ye? I remember he owns an orthopedic hospital. Has the marketing department had any contact with him?"
The man in the marketing department shook his head: "We rarely cooperate with small hospitals, and we have a general agent in Asia. They should be responsible for this matter. Two days ago, our Asian general agent asked about this matter
Some responses have been made to the matter and some articles have been published in response.”
Miller also nodded: "Well, I know this too. We have never stopped researching the adverse reactions of cobalt-chromium alloys, but there is very little research on anxiety disorders, because research on anxiety disorders and mania
.”
Pierce still asked cautiously: "This matter needs to be carefully studied by Dr. Miller. I don't want Hankison's reputation to be damaged."
The marketing department smiled: "General Manager, you don't have to worry about this. Although our main business at Hankison is the production and research and development of cobalt-chromium alloy prostheses, there are not a few people in the world who are also developing cobalt-chromium alloy prostheses.
Bai Ye's move is unwise, because cobalt-chromium alloy prostheses are still the mainstream in the market, and if there are no new products that can replace them, these rumors will be nothing more than a trivial matter."
Miller also nodded: "Bai Ye is challenging this industry. He doesn't even know how big the market he is facing is."
However, no matter what the people around him said, Pierce had his own plan in mind: "Well, let the Asian general agent have a meeting with Bai Ye and invite Bai Ye to be the scientific research professor of our company's market research and development department. If this can be done,
But let's leave it at that. If it doesn't work, we can give you some small means."
After the meeting, Pierce did not leave. Instead, he walked with Miller and asked, "When is the instruction manual for the cobalt-chromium alloy prosthesis we are currently using?"
Miller hesitated: "The head office asked us to use the 1999 research results!"
Pierce took a breath and fell silent.
……………………
……………………
Mitsui Tiansheng is the general agent of Hankison Company in Asia. After receiving the above instructions, he flew to Kyoto that day and made an appointment with Bai Ye the next day, hoping to have a friendly meeting.
Bai Ye was also a little curious about this visit, but he still met.
"Hello, Mr. Bai Ye, let me introduce myself. I am Mitsuda Mori, the Asia general agent of Hankison Company of Ferno Group." Mitsuda Mori bowed in greeting, with full courtesy and fluent English.
"Hello, Mr. Mitsui, please sit down. I wonder what you want to do with your visit today?"
"Today's unexpected visit is to invite you on behalf of the head office to become a consultant for our Hankison Company's product research and development department."
Bai Ye was even more surprised. He paid a sudden visit and invited himself to be the consultant of the company's R&D department. He didn't say whether he wanted to go or not, but there was definitely something going on.
"Sorry, I don't have any thoughts of going abroad at the moment. Besides, I don't have much experience in product research and development, so I'm afraid I'm not qualified."
Bai Ye thought while talking, Feinuo Group? This is a large company in the world's top 50. It invites itself to do product research and development. Feinuo... Hankison... Suddenly Bai Ye understood.
The thing about cobalt chromium alloy prostheses!
Did you see your own article?
It seems that my article has played a certain role.
And it attracted big fish all of a sudden!
Mitsui Tiansheng: "One more thing, I would like to excuse you. If Mr. Bai Ye can no longer study cobalt-chromium alloys, we are willing to provide your scientific research institute with a certain amount of scientific research funding for free and conduct research with your company at a preferential price.
Sales of products.”
"Hankson needs a partner and friend, and I think we can cooperate!"
Bai Ye smiled and said, "Sorry, we have partners now, and we have no shortage of scientific research funds."
Mitsuda Sheng saw that Bai Ye was not getting enough, and he was a little unhappy for a while: "Rejecting Hankison is not a wise choice. Mr. Bai shouldn't be an irrational person, right?"
Bai Ye shook his head: "Do you know what the core philosophy of a medical company is?"
"It's health. Patients' health is the driving force for research and development in the medical industry. What we doctors have to do is to choose a material that is more suitable for patients, rather than choosing a material that is more profitable."
"I think if your company has extra funds, it might as well do research on how to reduce the adverse reactions of cobalt-chromium alloys, instead of using public relations means to buy off the conscience of doctors."
After saying that, Bai Ye stood up and left. Bai Ye didn't have a good impression of Hankison. As such a big company, Bai Ye didn't believe that the other party didn't discover so many side effects of cobalt-chromium alloy prostheses. Cobalt-chromium alloy as a
Prostheses have been used for more than ten years.
It is still active in the market, and as a material that specializes in the development of orthopedic prostheses, Hankison has been leading the research on cobalt-chromium alloys for many years.
The more Bai Ye studies recently, the more he discovers many defects in cobalt-chromium alloys. Many of these defects are irreversible, such as the toxicity of cobalt-chromium ions, which causes irreversible damage to the nervous system, although there is no clear research yet.
result.
Moreover, Bai Ye discovered that this kind of toxicity is a disease caused by long-term chronicity. For example, cobalt-chromium toxicity can have an irritating effect on the gastrointestinal tract. However, if the patient has gastrointestinal disease and is in a highly sensitive state, then
, superimposed on cobalt-chromium toxicity, the impact on patients will be even greater!
Nowadays, many of the cobalt-chromium alloy prostheses currently used on the market are basically made of materials from Ferno Hankison Company. Regarding the adverse reactions and side effects of the product, solutions provided by Hankison Company are also used.
So for cobalt-chromium alloy prostheses, Ferno Group basically has the final say.
To put it bluntly, in this field, this person basically dominates the sky!
Bai Ye simply didn't believe that the other party had not discovered the seriousness of the pathological condition of cobalt-chromium alloy. If Bai Ye was doing it for money at the beginning, but now, something has shifted, and he could not accept such a definite harm.
Healthy products are constantly sold around the world.
Some time ago, Bai Ye specifically met with Zhou Luo in order to obtain some cobalt-chromium alloy prostheses. Zhou Luo was the original agent. Their company has agency rights for many foreign companies.
Zhou Luo told Bai Ye that Feinuo increased agency fees for domestic sales and agency, and it was very unequal in terms of contracts.
The reason is that the cobalt-chromium alloy prosthetic brand recognized by people in China is produced by Ferno Hankison Company.
Generally speaking, the price of cobalt-chromium alloy hip joints from domestic companies is only about 30,000, and if it is Ferno Hankison's, it is basically impossible to get it for 80,000.
Obviously it uses a large number of domestic markets, but it is very unfriendly to domestic patients.
The after-sales service is even worse. Generally speaking, after use of such expensive equipment, there are regular inspections and maintenance abroad, and even after-sales work for the treatment of adverse reactions, but in China, the Ferno Group is basically not responsible.
The attitude is that you love to buy and use.
This is what it means to be a big bully in a shop.
Now Bai Ye's research progress is getting faster and faster.
Bai Ye has even found clues about anxiety disorders.
On October 15th, the scientific research team discovered a phenomenon.
The human amygdala is responsible for the emotional management center. When the human body is under increased stress, the cortisol produced by the human body increases significantly. When cortisol is at a high level for a long time, it will damage the hippocampus and frontal nerves. These are easy Causes emotional instability.
Serotonins such as norepinephrine and dopamine can improve mood, increase happiness, relieve stress, and boost mood.
However, if free examples of cobalt-chromium exist, it will change the growth of glial cells in the brain and even cause metabolic abnormalities.
As a result, the supply of amino acids in the brain is insufficient, causing abnormal secretion of neurotransmitters, ultimately leading to the secretion of dopamine, norepinephrine, and serotonin.
This can affect people’s emotions and cause anxiety disorders!
The technical team has created relevant experimental models in rats. The results of this research are very significant and have clearly proven that cobalt-chromium alloy prostheses will significantly increase risk factors when the patient is in an abnormal state, and will definitely affect the human body's anxiety state.
Within the institute, under Bai Ye's call, more than 30 related articles have been written.
This time, Bai Ye did not plan to publish it himself, but directly called Ke Ao, the editor-in-chief of "Cell", hoping to publish a special issue on cobalt-chromium alloys.
After receiving the call, Keao hesitated: "Bai Ye, do you know the status of Feinuo Group in the United States?"
After Bai Ye heard the news, he didn't answer and asked directly: "I know that in the United States, magazines represent the rights and voices of the people. Has Feino already influenced the media?"
After Keao heard the news, he was extremely shocked, but he hesitated and said: "I'm not talking about this, this is a large interest group, and the publication of your article is likely to cause a major earthquake in the medical circle. "
Bai Ye: "That's better than a group of people whose illness is unknown. I don't believe that Feinuo has been studying cobalt-chromium alloys for so many years and has no idea at all. He is just hiding it."
Keao took a deep breath: "This matter is not a trivial matter. We should be well prepared. How many articles do you have, or do you have definite evidence to prove what you are studying?"
Bai Ye nodded: "Everyone is here! But...can you send it?"
After Bai Ye finished speaking, he also breathed out slowly. He felt a little embarrassed for Ke Ao. Indeed, this matter was no longer within Ke Ao's control.
Keao is just an editor-in-chief, an excellent employee of "Cell". He has a bright future. Maybe I shouldn't find him.
But the influence of "cell" is much greater than that of "Puze Latest Medicine"!
Keao: "Publish! I make the decision and publish the special issue. This is no small matter. Cobalt-chromium alloy prostheses are used by more than 2 million people around the world every day. I must let the people of the world see the true face of cobalt-chromium alloy!"
"America needs to speak out for justice!"
"You will send me the article later, and I will publish the special issue for all of it!"