Graduate students from the Institute of Surgery and researchers from the Digital Medicine Laboratory worked together to help look at the pictures. Unfortunately, after looking at thousands of pictures, only one picture showed virus structures inside the cells, and no tumor cells were observed.
Traces of apoptosis. In other pictures, whether of tumor cells or normal cells, no structure of the K virus was found.
These are all what Yang Ping expected, because the experiment cannot be smooth sailing, and there will definitely be problems of one kind or another during the period. The success of the experiment is the process of constantly solving problems and correcting the route until it finally succeeds. Many experiments even after a huge effort
It is common to work hard and do countless things but still fail in the end.
What's more, one of these pictures now shows the structure of K virus inside tumor cells. In fact, this is a huge success, indicating that K virus can successfully reach tumor cells and then infect them.
There are several possibilities for this situation. The first possibility is that the virus is mostly eliminated by the immune system during the process of being transported by the blood to the tumor. The second possibility is that many viruses have reached the tumor, and the success rate of infecting tumor cells is extremely low.
Third, the virus that infects tumor cells can initiate the cell's apoptotic program, but the cells that initiate the apoptotic program are not captured. Fourth, it is possible that the virus cannot initiate apoptotic cells.
No matter how many possibilities there are, one thing is certain, K virus can infect tumor cells, it just depends on its ability and probability. Now this picture is the most powerful evidence.
There are tens of thousands of pictures taken electronically. It is too inefficient to rely on human power to view the pictures, and it is also unhealthy for the eyes.
Sharpening the knife and chopping wood without missing a beat, Yang Ping decided to use computer assistance. He suggested that Director He's team develop an artificial intelligence model to help distinguish these pictures.
In fact, it is not difficult for Director He and his team to develop such a model, because now they have an artificial intelligence model for image recognition, but it is mainly used for viewing pathological slices and imaging pictures. This model is widely used in pathological slices and imaging.
His ability to read pictures is very mature and has surpassed that of most doctors.
Doctors may have a hard time reading hundreds of pathological slides a day, but artificial intelligence can read tens of thousands or hundreds of thousands of pictures in a few seconds. This efficiency has been used in medicine. Many hospitals will be able to fully automate the viewing of pathological slides in the future.
There is no need for a pathologist to read the slides. The pathologist's job is only to make pathological slides. If the pathological slide production can be automated, then the pathologist only needs to simply process the pathological specimens.
Any artificial intelligence needs a large amount of data to feed, otherwise the artificial intelligence will be just an "idiot". In this experiment, there is no precedent for analyzing the extracted cell electron microscope pictures, so there is no data to feed the artificial intelligence.
Although Professor He has developed an imaging artificial intelligence model using digital human technology, which is specifically used for intelligent reading of films, such as X-rays, MRI and CT films, this model has been fed a large amount of data and has evolved well.
But for the pictures of tumor cells under the electron microscope, these are brand-new pictures and there is not a lot of data to feed, so the artificial model cannot evolve and is not of much use.
Professor He can only develop an image analysis engine based on the experience summarized by Yang Ping. This engine does not need to be fed by big data. It can analyze the image. If the analyzed structure is the same as that of tumor cells and there are no redundant structures, the image
It is marked as non-infectious.
If extra structures are found inside the cell, the extra structures are immediately extracted separately and entered into the next analysis program. If the morphological structure is partially or completely the same as that of the virus, it is marked as infected.
If uncertain pictures are marked as unclear, these pictures will be left for manual analysis. Afterwards, experience will be summarized based on the results of manual analysis, and the experience will be applied to the improvement of the model. In this way, its engine will become more and more advanced, and its recognition capabilities will become better and better.
Coming stronger and stronger.
This is actually similar to the engine used by anti-virus software to analyze computer viruses. The difference is that anti-virus software analyzes the code of computer viruses. This software analyzes electron microscope pictures, but the general principles are similar.
In short, Yang Ping will now work closely with Professor He's team to develop various subdivision models to assist experiments. When the large artificial intelligence model is released, the large model will be used to assist scientific research and greatly increase the efficiency of scientific research.
Amplitude increased.
Professor He cannot develop a model in a day or two. Although he has acquired basic models that can be used, and his team has digested and absorbed these models, it will take a certain amount of time to use these models to modify them.
When Ruixing Medical acquired the model, one of the models was specialized in laboratory biological image recognition. Professor He's team could improve on this model, which would save a lot of time.
In fact, acquisition is not a bad thing. If its technology can be digested and absorbed after the acquisition, it can greatly shorten the research and development time and keep pace with the international world.
Yang Ping decided to temporarily stop reading the pictures and wait for Professor He's image recognition engine to be developed before continuing to read the next pictures. He wanted to focus on modifying the structure of the virus.
Judging from the data collected in the first experiment, the K virus must have caused a strong reaction in Sisi's body's immune system. This reaction is very dangerous and sometimes fatal.
Therefore, Yang Ping’s first task now is to change the implantation position of the K virus. This position is very important and directly affects the interaction between the K virus and the human immune system. It must reduce its stimulation of the immune system. It is best to not cause adverse symptoms like some viruses.
, or just cause mild, transient flu symptoms.
---
After Sisi experienced a high fever caused by the first injection of K virus, her whole body suffered a huge blow, which took time to recover. Fortunately, the functions of various important organs have not been significantly damaged so far.
This chapter is not over, please click on the next page to continue reading! After the operation, Yang Ping continuously collected MRI images of each of Sisi's metastases. He chose MRI as the imaging examination. Its biggest advantage is that there is no ionizing radiation, unlike
CT, PET-CT, etc. must contain ionizing radiation, and continuous application will have a negative impact on the body.
Tumor marker monitoring has also officially begun. A tube of blood must be drawn almost every day for these tests to dynamically monitor changes in tumor markers.
After the high fever, Sisi's appetite was not very good, but the little girl was very sensible. She knew that recovery would be slower if she didn't eat, so she forced herself to eat more so that she would recover as quickly as possible. Her mother also tried her best to do it in different ways.
He gave her something to eat, but unfortunately, the function of his taste buds had not yet recovered, and no matter how delicious the food was, it tasted like nothing in Sisi's mouth.
In fact, the situation at that time was equivalent to an escape from death. A new virus was catastrophic to the human body's immune system, but fortunately, it was not too new, and it seemed that it was still similar to the original virus.
Similarity, the human body still has the ability to kill it and has the experience to deal with it.
For example, in some areas of the Arctic, many viruses are frozen in the ice. If one day the ice melts and these viruses come back to life, it will be a huge threat to humans, because human immunity has not dealt with them and lacks immunity to them.
combat experience.
Viruses that humans usually come into contact with, such as various viruses that cause colds, humans have frequently dealt with them or their ancestors during the long process of evolution. Our immunity has enough experience in dealing with them, so in most cases, we can defeat them.
It only fails in rare cases.
Yang Ping had the first conversation with Sisi's parents after the first experiment. Yang Ping fed back the results of the experiment to them. They said that no matter what the result was, they would fully cooperate with Yang Ping and let Yang Ping not feel any pressure.
They could bear all the consequences and were very grateful to Yang Ping for doing his best for Sisi.
Mr. and Mrs. Hermes have always been concerned about Sisi's condition. After this laboratory, they also came to Yang Ping to understand the situation. Sisi is now their goddaughter.
After Yang Ping introduced the results of the experiment, Hermes sighed:
"I do have a fate with this child, and I feel sorry for him in my heart, just like my own daughter. Professor Yang, please tell me where money is needed. I can't help with other things, but I can still help with money matters.
Just tell me what kind of equipment you want to buy. I heard that this kind of experimental treatment is quite expensive.
, those laboratory equipment are very expensive, remember to tell me what equipment you want, thirty years in Hedong, thirty years in Hexi, now brother, I am not like before, now I have a lot of money, to tell you the truth
, I now have not only gold mines and diamond mines in Africa, but also lithium mines and iron ores.
, Wealth luck has been very good recently. These mines are not only high in content and good in quality, but also very easy to mine and cost very low, so they are very profitable to sell. Not to mention too much, it is easy to get billions of funds now.
Tens of billions is not a problem, hundreds of billions is not impossible, nothing else, now
Brother, I just have a lot of money. You can use me wherever money is needed. Lao Huang's place is engaged in medical technology. It makes money slowly and there are many places to use money. It's not like me and the money printing machine, so you have nothing to do with me.
Don't be polite, money is just for spending, and as long as it's spent in the right place, I won't feel bad about it."
Although Hermès is rich, his feelings are still very sincere, and Yang Ping understands this.
"This is not a matter of money. Now we are encountering some problems. These problems need to be solved one by one. However, although the results of the first experimental treatment are not very good, they are not the worst either. This is normal. In the world,
Many things are like this, good or bad, this is pretty good, just wait patiently." Yang Ping knew that he was anxious, so he comforted her.
"Professor Yang, where is this little girl Sisi? How should I put it? I just said that I am destined to her. To be honest with you, I am not afraid of your laughter. I was planning to jump off the surgical building after I went bankrupt. Really, I
At that time, I had lost all my thoughts and had no love in life. But after seeing Sisi, my mood completely changed.
Wow, a little girl of eight or nine years old who is terminally ill can be so optimistic, so positive, and see life and death so clearly. I am almost forty years old and in good health. You even helped me heal one of my legs. I
Is there any reason to cherish life and the opportunity to live in this world?"
As he spoke, Hermès actually shed tears. His wife handed him a tissue, and he wiped it, and continued: "It's not anyone else, so don't laugh at me. This little girl will help me open another world, that world."
It is full of sunshine and beauty. So now I have seen through it. I have so much money in my hands. If I don’t use it to do something meaningful, the money will be wasted in my hands. People
Well, living in this world, whether it is long or short, you have to do something meaningful so that your life is not in vain. So let me tell you, Professor Yang, you are a medical genius. If I have all this money
Giving you tinkering is better than giving it to others. You will definitely be able to come up with something, and the things you tinker with will definitely save many people’s lives, so I feel that my money is also meaningful."
"Isn't Ruixing Medical currently engaged in artificial intelligence with Nandu University? I heard that this has been very helpful to Sisi's experiment. Ruixing has set up a special company to study this. I heard that it is very expensive.
Otherwise, how about I give a few billion to Lao Huang first and let them tinker with artificial intelligence?" Hermès asked.
"This is a very risky business, and we are currently in the stage of losing money," Yang Ping said.
"Oh, I can make a donation, no matter what the risks are. I have said that the money is not used to make money, but to generate some meaning. As for me, I am uneducated and can't speak. I used to dig coal.
, Nowadays, when digging for gold, you can only make money by doing these unskilled things, so don’t dislike it.” Hermès has to give away the money today anyway, otherwise it will feel uncomfortable.
''If you are really serious, then I will tell them that when you invest, you have to bear the risk anyway."
"No problem. As a gold digger, why should I be afraid of risks? As long as there is still gold in the soil, I am not afraid of risks. Besides, what will happen if the money is gone? The worst I can do is to sell songs on the overpass again."
Hermès now has money but no place to put it. As long as Yang Ping needs money, he will throw money into it regardless of whether he can get a return on investment in the future. Some random investment experts suggested that he invest in this and that, but he refused and did all that.
Useless.
"Professor He of Nandu University seems to be doing any research that requires money. I'll donate a few hundred million to it. I'll donate another billion to several of your laboratories here. There's also the Genetics Laboratory of Nandu Medical University. I heard that
Your uncle's lover is in charge, and I've spent hundreds of millions to donate to her project. Who else is there? Oh, Nandu Fuyi, I'll donate another sum." Hermes crossed his fingers to plan how to spend the money.
.
this?
What a rich man!
"besides!"
Hermes remembered: "Um, didn't I hear that Lao Huang was fighting with others recently? I will use a few mines to back him up."