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Chapter 1004, Vaccinia Prevention

After quickly collecting some samples, Li Anyuan also quickly took people out of this plague city. Almost everyone here was infected with smallpox. In addition, they were so ignorant that they would rather believe in ghosts and gods than what Ming Dynasty provided.

With the prevention and control methods, no one in this city can escape death.

"Professor Li, from the analysis of samples collected from various places, all smallpox viruses are no different from the smallpox viruses that appeared in our country in Ming Dynasty. There is no difference."

Back in Baiyin Port, Li Anyuan's team never stopped, running around, constantly collecting samples, and analyzing the epidemic situation in the entire Aztec Kingdom.

"Judging from the current situation, the epidemic in the Aztec Kingdom has reached the edge of getting out of control. It may completely erupt at any time. By then, it will not only destroy the entire Aztec Kingdom, but also our Ming Dynasty.

These colonial towns will also be implicated."

"We must find a way to solve this problem as soon as possible."

After Li Anyuan listened to the report of his subordinates, he frowned.

The situation was even worse than what I saw. The smallpox virus had spread on a large scale. The key was that these people in the Aztec Kingdom were very superstitious and did not strictly follow the requirements of the Ming Dynasty. As a result, smallpox

The spread of the virus is beyond imagination.

"Isolation is definitely not enough. Now we can only try the cowpox prevention method mentioned by Mr. Liu."

Although the smallpox virus is terrible, has a high mortality rate, and is very transmissible, a lot of experience has been accumulated in the long-term fight against the smallpox virus since ancient times.

In the Song Dynasty, there was a medical book "The Final Theory of Acne" that recorded relevant matters. It mentioned that there were people in Sichuan who were good at vaccination, and people who had been vaccinated would never get smallpox again.

From here we can know that there has been a way to deal with smallpox in the past, and that is to achieve the prevention effect through variola vaccination.

However, the method of variolation will cause serious adverse reactions, and even a certain proportion of fatalities, and is far less safe than the cowpox vaccination method that became popular in later generations.

Li Anyuan came to Huanghuangzhou this time. On the one hand, he naturally wanted to find a way to control the spread of the smallpox virus in Huanghuangzhou and prevent the smallpox virus from spreading to the Ming Dynasty.

You must know that the population in the Ming Dynasty, especially in the Beijing-Tianjin area, is too dense. Once people carrying the smallpox virus flow into the Beijing-Tianjin area, the consequences will be unimaginable.

Therefore, the source must be blocked to prevent the smallpox virus from spreading to the Ming Dynasty.

Of course, the most important thing is to find ways to prevent and treat the smallpox virus. Preventing all the time is definitely not the answer.

The population in the Beijing-Tianjin area is very large and dense, and with the development of shipping and highways, not only the exchanges between Ming Dynasty have become closer and more frequent, but the exchanges between Ming Dynasty and other parts of the world will also become more frequent.

are more intensive and frequent.

This means that many endemic diseases may be transmitted to the Ming Dynasty, and smallpox is just one of them. Without strong medical technology and medical teams, it is very likely that the history of Europeans will repeat when facing terrible diseases.

.

The most effective way to deal with smallpox is prevention. If everyone is vaccinated against smallpox, there will naturally be nothing to fear.

Li Anyuan soon found Wu Lin, the magistrate of Baiyingang, again and put forward his opinions and requirements to him.

"Professor Li, please don't worry. I will immediately contact Montezuma II of the Aztec Kingdom and ask him to get some people over for experiments first."

After listening to Li Anyuan's words, Wu Lin realized the seriousness of this matter and clearly understood why the court sent Li Anyuan here.

This is not just to help the Aztec Kingdom, but also to research ways to prevent smallpox for the Ming Dynasty.

"Good work!"

Li Anyuan quickly expressed his thanks, and then made some other requests, such as a separate isolation area, supplies needed for treatment, and a certain amount of manpower.

Wu Lin acted very quickly. In just a few days, he got more than a hundred people from the Aztec Kingdom. It was very easy and simple.

Tian Erniu conquered the Aztec Kingdom with force and religion, convincing them that the Ming Dynasty and they were all the people of the Sun God, but they made mistakes and were exiled here, and now the God of Plague has descended.

to punish them.

For this reason, the Aztec Kingdom even announced that it would pay double the gold and silver tribute this year and build a larger pyramid to atone their sins to the Sun God and ask the God to forgive their sins.

Regarding the Ming Dynasty's request, the Aztec Kingdom agreed without hesitation and sent more than a hundred people to participate in Li Anyuan's experiment.

In a separate and isolated area of ​​Baiyin Port, more than a hundred descendants of the Yin and Shang Dynasties, including men and women, old and young, are queuing up to be vaccinated with cowpox.

Li Anyuan, wearing a white coat and a mask, carefully watched his apprentices inoculate these people.

"I don't know if this cowpox vaccination method can prevent smallpox. If it doesn't, I'm afraid the Golden Continent will have to be sealed off by then."

"But there are too many, too many people who have married local women as wives and concubines, and are left with millions of children. With so many people, if this method does not work, I am afraid that the only way to prevent it is to rely on forced isolation.

Already."

Li Anyuan looked at the team in front of him with sadness on his face.

Because it is experimental in nature, Li Anyuan's team also uses several methods of borrowing seeds. There are traditional methods of borrowing seeds, which include drying cowpox powder and blowing it into the nostrils, wiping the body with clothes soaked in cowpox, and

There are people who prick the skin directly with needles on their hands and feet, and then get infected with cowpox... Various methods of borrowing seeds are all tentative, but fortunately there are not many people.

Therefore, the speed was very fast. In less than an hour, more than a hundred local indigenous people had completed the vaccination.

Perhaps it was because the local aborigines of Golden Continent lacked immunity to the smallpox virus. After the vaccination, more than a hundred people immediately developed symptoms of discomfort on that day alone.

"Record everything in detail, what symptoms each person has, what their body temperature is, what their pulse is, how their heartbeat is, whether they have fever, etc."

"This information is very important and must be detailed!"

Li Anyuan's team quickly became busy. This was an extremely rare experiment.

You must know that this experiment is conducted with human lives, and the risk is very high. Once the experiment fails, more than a hundred people will most likely die due to being infected with the smallpox virus.

It is forbidden to conduct experiments on living people.

But medicine sometimes has to be like this, especially in this era where experiments on mice are not yet known. If you want to quickly know the therapeutic effect of a drug on a certain disease, the simplest and most direct way is to use the human body

test.

This is why Liu Jin sent them to Golden Continent, because Golden Continent happens to have a large number of experimental subjects and a large amount of experimental materials, which is enough for Li Anyuan to study a method of borrowing cowpox.

come out.

The entire team quickly became busy, classifying and summarizing each patient in detail, and at the same time began to test the symptoms of these people.

"Judging from the current situation, the method of using acupuncture to prick blood is the most effective method. All people who used this method, whether on their hands or legs, were infected with smallpox in the first time, and began to appear.

Illnesses associated with smallpox.”

"Judging from the current situation, everyone's symptoms are within control. Although there are some herpes on the body, they are very small and disappear quickly."

"The symptoms of the vaccinated patients are very mild, far less than the symptoms of variola vaccination in Daming, and the adverse reactions are much lighter."

"Scabs appeared at the site of vaccination. From the removed scabs, you can see through a microscope that there is smallpox virus in them, which means that you have been infected with smallpox virus."

Li Anyuan is constantly analyzing and summarizing every day.

After a few days, each of the more than a hundred descendants of the Yin Shang who had been vaccinated with cowpox recovered completely, and there was nothing wrong with them.

"Everything is fine. Now comes the most critical part, which is to see if antibodies have been produced. If antibodies have been produced, it means that the vaccinia vaccination method is indeed feasible."

"Compared with the traditional variola vaccination method, the cowpox vaccination method is safer and more reliable, and the side effects are very small. Even for these descendants of the Yin Shang Dynasty, their side effects are not very big. They are just feeling unwell and can take a rest for a day or two.

After a few days, you will be back to your original state soon."

Seeing the results of the experiment, Li Anyuan's team couldn't help but cheer, because judging from the results of the experiment, no one died among more than a hundred people. Although some people had some serious adverse reactions during the period, they recovered quickly.

.

"Inject them with smallpox!"

Li Anyuan suppressed the excitement in his heart. If he could develop a method to prevent smallpox virus with cowpox, his name would be written into history.

He would become the first person in history to develop a truly effective anti-smallpox virus.

Smallpox, this is an extremely terrible disease, a disease that makes people ashamed.

In Daming, there are reported cases every year, and at least thousands of people die from smallpox almost every year. This is because Daming has developed a relatively mature and reliable response method.

In Europe, due to the lack of effective countermeasures, smallpox is just like the Black Death in the Middle Ages. It has claimed many lives. It is too contagious and has a very high mortality rate.

This is a disease that makes people jealous, but now I am about to master the method of restraining it.


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