Bai Ye took out the thesis and proposal report given to him by his tutor at that time: "Clinical Observation of Danqi Huoxue Pills on Coronary Heart Disease".
Danqi Huoxue Pill is an empirical prescription commonly used by Mr. Liu to treat coronary heart disease. After so many years of clinical efficacy observation, it is ready to be made into a patent medicine.
The paper has a detailed introduction to Danqi Huoxue Pills. In fact, the prescription is very simple, with only two traditional Chinese medicines: salvia miltiorrhiza and notoginseng.
However, many experiments have been done, including clinical observations and animal experiments, which are very detailed.
Part of the pharmacological and toxicological research on drugs has also been done. In fact, it can be considered a relatively complete research on patent medicines.
However, drugs are nothing else. All the ingredients must be clearly understood, and then each ingredient must be analyzed to prove its effect on the human body. Even pharmacokinetics and pharmacokinetics must be thoroughly studied. After several clinical phases,
Only after testing can it be launched in foreign markets.
Of course, what Senior Sister Bai Ye is doing is just a doctoral project of her own, which is a learning process. It is not about applying for a patent or anything like that. As long as it is made into a patent medicine, it will probably only be sold in the hospital and will not go to the market.
Not to mention her, not even a big company has a proprietary Chinese medicine on the market abroad, so Bai Ye's work is actually a training and learning process for Liu Boli.
However, although Liu Boli didn't take it seriously, Bai Ye still cared about it. This was the first test his instructor had given him, and Bai Ye still wanted to do well.
After Bai Ye read it carefully, he collected the medicinal ingredients and modern pharmacological research of Salvia miltiorrhiza and Panax notoginseng on the Internet.
Bai Ye has a foundation in pharmacology, and his skill level is already lv4: 12012/30000. However, to analyze a drug specifically, what is needed is not pharmacology, but chemistry.
For a whole day, Bai Ye searched the database in the dormitory for information and downloaded papers on modern research on Salvia miltiorrhiza and Panax notoginseng.
However, Bai Ye suddenly felt a little dizzy when he saw so many chemical formulas. It takes many steps to separate these various substances. For example, some organic compound molecules have few hydrophilic groups.
Some have high polarity and are repellent to oil, some have few hydrophilic groups, some are low in polarity and are repellent to water. There are also salting out methods and so on.
There are also various physical methods for extraction and separation, such as fractionation, adsorption, etc.
Bai Ye didn't do much research on pharmacy, but Bai Ye had an idea. It was June, and there were still classes at the School of Traditional Chinese Medicine. Thinking of this, he got up and called Fatty and asked him to give him the curriculum for the school's pharmacy major.
Send one copy.
Fatty was very fast, and he sent me a course schedule in a short time.
The main courses of pharmacy include chemistry and pharmacy, and the main subjects include organic chemistry, medicinal chemistry, biochemistry, physical chemistry, etc.
Bai Ye does not need to study all of them, but it is still necessary to study some key subjects.
Thinking of this, Bai Ye decided to take classes!
…………
Now it's the exam month, a month where attendance is counted and key points are drawn. After Bai Ye left, there were a lot of people. The back row was full, leaving only a few empty seats in the first row.
Bai Ye had no choice but to find an opportunity to sit down in the first row.
Today we are talking about Medicinal Chemistry, which is a newly added subject after 2011. It studies drugs from the molecular level and analyzes the relationship between the chemical structure and physical and chemical properties of drugs.
Bai Ye listened very carefully. Although he didn't have a textbook, he never stopped taking notes in his hand.
However, after two or three days, Bai Ye found that this knowledge was not enough, and most importantly, it was not targeted enough. In desperation, Bai Ye went to the library to find books to study on his own.
In this way, you can study in a targeted manner, and then go to the teacher after encountering problems, which may be more efficient.
If you simply consider the major you want to study, pharmaceutical analysis is actually more suitable. This is a branch of analytical chemistry.
After reading some books in two days, Bai Ye still felt a little confused and confused.
So Bai Ye found Zhang Hanlin, hoping to apply for a laboratory and learn while experimenting. Maybe the chance would be better. After all, this is a highly experimental subject.
Zhang Hanlin is basically obedient to Bai Ye now. He is now the school's mascot. He readily agreed and directly called the dean of the School of Traditional Chinese Medicine and asked Bai Ye to come find him.
When the dean of the School of Traditional Chinese Medicine heard that Bai Ye was coming, he opened his mouth with joy and received Bai Ye personally.
Nowadays, everyone in the entire University of Traditional Chinese Medicine knows about Bai Ye. This is a cornucopia of mascots. If this genius shows some talent in pharmacy, publishes a few top papers, or if... he accidentally makes some major discovery!
Can I also apply for a national degree or something?
Thinking of this, Zhou Mao, the dean of the School of Traditional Chinese Medicine, saw Bai Ye coming in and said kindly: "Come on, come on, welcome to our School of Traditional Chinese Medicine. Xiao Liu, go and give Xiao Ye a cup of tea."
Bai Ye was embarrassed and a little flattered. He was here to ask for help, right? It seemed like the other way around.
He quickly said, "Dean Zhou, please stop being busy. I came here to ask for something."
Zhou Mao looked at Bai Ye with a crooked smile and said, "Come on, sit down and talk slowly. Is there anything you need Uncle Zhou's help with?"
"It's like this, Dean Zhou, the graduate tutor I applied for, Academician Liu Boli, gave me a small task and asked me to conduct research on the pharmaceutical ingredients of a drug called Danqi Huoxue Pills. I have been reading the book in the past two days.
, I always feel that I don’t know what to do, so I hope to apply for a laboratory in the School of Pharmacy with Dean Zhou, so that I can do experimental research myself.”
Zhou Mao nodded after listening to Bai Ye's words. It is estimated that this is an assessment or training given by Mr. Liu to Bai Ye. After all, after entering the clinic, he has not had much contact with experiments. If he develops a more rigorous and mature scientific research attitude and
This idea is undoubtedly a good thing for future development. Thinking of this, he also became serious: "Xiao Ye, how much do you know about pharmacy?"
Bai Ye shook his head: "I only have some research on clinical pharmacy, but I am not very good at specific drug analysis, so I took a few classes at our college and read a few books in the past two days."
After Zhou Mao heard this, he thought for a while and said: "Well, actually pharmacy is a relatively comprehensive subject. Let's do this. I will approve a laboratory for you, and you can get some from Teacher Yang in the equipment room.
The reagents are convenient for you to conduct experiments. If you have any questions during the experiment, you can come to me directly."
Bai Ye looked happy and stood up quickly to thank: "Thank you very much, Teacher Zhou!"
Zhou Mao waved his hand and said with a smile: "You're welcome. If you don't have enough materials and reagents, just ask. I'll approve it for you. Do it well. When you're done, show me first and I'll check it for you. Otherwise, when you get to Mr. Liu's place, you'll still have to wait.
They say my University of Traditional Chinese Medicine is delaying talents, haha."