"Liu Yue discovered a strange phenomenon during the experiment. When exposed to a harsh environment, the permeability of the cell membrane surface of normal intestinal epithelial cells will undergo some changes. This change is irreversible. When the cell membrane surface
When the channels with the outside world change, many harmful environmental substances can enter the cell through the cell membrane, destroy the mitochondria in the cell, and completely affect the metabolism of the mitochondria. If this happens for a long time, it will induce nucleic acid in the nucleus."
When this news reached everyone's ears, in-depth research was quickly carried out. This is the next research feature of the experiment.
At this time, Bai Ye realized that the current research team was completely different from the original. Their ability to act, execution and even creativity were extremely strong. They were sensitive enough in the discovery and innovation of new substances.
.
This is especially true for Liu Yue!
This is a genius, he is very good at finding the glimmer of specificity among the many differences.
In this way, everyone is involved in this serious matter, and Bai Ye can't bother to study with Bona now, because he found an even stranger problem, because he didn't just have accumulated intestinal tracts on those deteriorated cell membranes.
There is also a bacterial colony named: nbod-31. This bacterial colony actually covers the surface of the intestinal tract and secretes a large amount of substances. These substances seriously damage the permeability of the cell membrane surface. It is very likely that this nbod-
Colony No. 31 is one of the main pathogenic bacteria responsible for intestinal cancer.
After reaching this conclusion, Bai Ye was able to continue studying. He is now at lv6 in microbial bioengineering and lv6 in cell engineering. The dual lv6 skills allow Bai Ye to study this thing with ease and even mastery.
Bai Ye immediately returned to his secret base and began the next step of research. He first used individually cultured nbod-31 colonies to implant into the large intestine of guinea pigs and observed them.
Not long after, just one month later, he surprisingly discovered that the symptoms of intestinal cancer in one group of guinea pigs worsened and the spread of cancer cells significantly accelerated. However, the onset of intestinal cancer was also discovered in the second group of healthy guinea pigs without cancer cells.
signs, which means that this colony may really be a deadly colony.
However, Bai Ye didn't find any introduction about nbod in this aspect on the intestinal flora map?
What does this mean?
There must be something wrong!
Bai Ye was a little confused as to what the problem was.
On an accidental weekend, Bona, Mexican Bai Ye and others were sitting together to discuss issues. Jiali suddenly asked:
"Cancer cells are actually different from normal cells. Their nucleotides have changed. Especially in the current treatment of targeted drugs, many of them simply act on cancer cells. Professor Bai Ye,
You have done a lot of research on microorganisms. I have a question, that is, is there variation in the bacterial flora?"
Bai Ye was instantly shocked by this question!
yes!
Has he observed whether the nbod-31 colony will mutate, or should I say evolve?
Mexico also said excitedly: "Yes! I have always ignored a problem. The metabolism of human cells is not as fast as those of microorganisms. Their lifespan is very short, but equally, they will multiply rapidly, and
It will change according to changes in the environment, and I also think this is a direction worth studying."
"Professor Bai Ye, I think this thing should be studied more intensively, especially in terms of before and after comparison of cancer cells. It is very meaningful. Especially in terms of RNA and DNA of bacterial colonies, this subtle difference is likely to lead to mutation of the bacterial flora.
."
After Bai Ye heard this, his mind became brighter instantly.
This idea is very creative. I thought I had all the intestinal flora maps, but I ignored a very important mutation reaction effect.
One of the biggest characteristics of microorganisms is mutation. Once they mutate, it becomes another new type of bacteria.
The more Bai Ye thought about it, the more excited he became. A series of reactions instantly formed in his mind. Thinking of this, he quickly stood up and walked outside.
When everyone saw Bai Ye leaving in such a hurry, they were suddenly stunned, but then looked at each other and smiled, because they had also experienced such a thing.
Creation is more valuable than etiquette.
After Bai Ye left, everyone had no intention of staying any longer. They all got up and continued their own research.
……………………
……………………
In the laboratory, Bai Ye immediately started what he wanted to do.
The first thing he had to do was to compare the flora. He extracted the nbod-31 flora in the guinea pigs with intestinal cancer, carefully placed it in the test tube, and then put the normal flora in the flora library into another
in a laboratory vessel.
Showing the cell membrane of the bacterial colony, after the nbod-31 colony was broken, there were scattered cell walls and cell membranes in the culture dish. nbod-31, like most bacteria, is a prokaryotic organism with no nuclear membrane and only one nucleoid.
Moreover, in addition to the DNA in the nucleoid region, there is also a genetic factor that can be transcribed and translated independently, called a plasmid. A plasmid is a naked circular double-stranded DNA molecule that contains 2 to 200 genes and can carry out genetic information.
Self-replicates and sometimes can be integrated into nuclear DNA. Plasmid DNA is very important in genetic engineering research and is often used as a vector for gene recombination and gene transfer.
The main comparison work is to compare the DNA from the plasmid and the nuclear region.
Finding and looking for a job is difficult and requires a lot of patience, because there is a good chance that you will find nothing.
But what Bai Ye lacks most is patience, otherwise he wouldn't have stayed in a private office for more than half a year.
Bai Ye began to search frantically, looking for different sequence fragments from the broken DNA fragments. He missed every one, but still found nothing, which made Bai Ye a little anxious.
Is it really true that nothing has changed?
He suddenly remembered that he had another [deep scan]!
This month's idea was not used, so Bai Ye gained confidence.
Bai Ye took a deep breath and prepared more than a dozen nbod-31 bacterial culture dishes of different levels in the laboratory. After preparation, Bai Ye first turned on the deep scan.
This is the last [Deep Scan] he has left, and Bai Ye cherishes it very much.
Bai Ye blinked, and when he opened his eyes again, the world in front of him suddenly changed!
But this time, Bai Ye is not as strange as the previous two times. On the contrary, this feeling is very charming, because... it's a bit like God's perspective!
Bai Ye feels that if [Deep Scan] can be renamed, it can be renamed [God's Perspective]!